Overview
- Editors:
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Urs Peter Schlunegger
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Department of Organic Chemistry, University of Bern, Bern, Switzerland
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Table of contents (11 papers)
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Front Matter
Pages I-VIII
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- Timm Anke, Wolfgang Steglich
Pages 9-25
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- Howard R. Morris, Anne Dell, Maria Panico, Roy McDowell, Ashraf Chatterjee
Pages 97-147
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- Thaiya Krishnamurthy, Marguerite E. Brooks, Donald F. Hunt, Jeffrey Shabanowitz, Shuian Chen, Terry Lee
Pages 149-160
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About this book
Over the past few years there has been a remarkable and rapid development of modern analytical methods, and the fields of nuclear magnetic resonance and mass spectrometry have been no exception. In addition to being able to do "more and faster", new innovative techniques have also arisen to contribute to a growing understanding of the relationship between chemical structure and biological activity. In order to explore a few of the more interesting points of those developments and applications, a seminar "From Biological Activity to Structure" was organized from September 5-7, 1988, at Interlaken. The four invited speakers, Richard M. Caprioli, Howard R. Morris, Wolfgang Steglich and Dudley H. Williams were kind enough to attend and discuss many facets of their research, especially methodological and technical developments and their applications to specific problems. Participants were introduced to continuous flow FAB (fast atom bombardment) and its use, for example, in the real time monitoring of biochemical reactions in vitro and in vivo; the structural elucidation of secondary metabolites from fungi; the analysis of molecule-receptor interactions; the determination of posttranslational modifications of peptides; and the location of S-S bridges in determining the tertiary structure of proteins.
Editors and Affiliations
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Department of Organic Chemistry, University of Bern, Bern, Switzerland
Urs Peter Schlunegger
