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Chromosomal Breakage in Response to Cross-linking Agents in the Diagnosis of Fanconi Anemia

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Fanconi Anemia

Abstract

The Fanconi anemia (FA) syndrome was originally described by Guido Fanconi in 1927. In his report he described three brothers with a condition resembling pernicious anemia. Evidently the anemia was the main symptom of the disease. Subsequently, other clinical symptoms (e.g., thumb aplasia and other skeletal abnormalities, café au lait spots, and growth retardation) frequently observed in FA have been described (Nilsson 1960; Fanconi 1967).

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Authors
  1. F. Arwert
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  2. M. L. Kwee
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Editor information

Editors and Affiliations

  1. Institut für Humangenetik und Anthropologie, der Universität Heidelberg, Im Neuenheimer Feld 328, D-6900, Heidelberg 1, Federal Republic of Germany

    Traute M. Schroeder-Kurth

  2. Laboratory for Investigative Dermatology, The Rockefeller University, 1230 York Avenue, 10021-6399, New York, NY, USA

    Arleen D. Auerbach Ph. D.

  3. Fachbereich 9 Genetik, Universität Gesamthochschule Essen, Universitätsstraße 5, D-4300, Essen 1, Federal Republic of Germany

    GĂĽnter Obe

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© 1989 Springer-Verlag Berlin Heidelberg

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Arwert, F., Kwee, M.L. (1989). Chromosomal Breakage in Response to Cross-linking Agents in the Diagnosis of Fanconi Anemia. In: Schroeder-Kurth, T.M., Auerbach, A.D., Obe, G. (eds) Fanconi Anemia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74179-1_7

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  • DOI: https://doi.org/10.1007/978-3-642-74179-1_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74181-4

  • Online ISBN: 978-3-642-74179-1

  • eBook Packages: Springer Book Archive

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