Abstract
As a rule c-myc appears to be expressed in all proliferating cells and is turned off in quiescent (GO) cells. After induction, myc mRNA and protein appear within hours in both fibroblasts and lymphoid cells, prior to the onset of cellular DNA synthesis (Campisi et al., 1984, Kelly et al., 1983). The correlation between c-myc expression and growth state suggests that c-myc is involved in growth control.
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References
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© 1988 Springer-Verlag Berlin · Heidelberg
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Henriksson, M., Classon, M., Hammarskjöld, ML., Klein, G., Sumegi, J. (1988). The Replication Activity of SV40 DNA Correlates with the Level of c-myc Expression in Human Tumor Cell Lines. In: Potter, M., Melchers, F. (eds) Mechanisms in B-Cell Neoplasia 1988. Current Topics in Microbiology and Immunology, vol 141. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74006-0_27
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DOI: https://doi.org/10.1007/978-3-642-74006-0_27
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