Abstract
A preliminary study with EEG topographical mapping in carefully characterised schizophrenic patients will be reported in which patients were clearly differentiated from controls. The majority of test conditions involved functional activation with neuropsychological tests validated on neurological patients. Group differences were seldom found in the resting EEG. Before describing the results other reports using new EEG imaging procedures will be outlined and some contemporary approaches to the investigation of central nervous system dysfunction in schizophrenia will be briefly reviewed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Andrews HB, Honse AO, Cooper JE, Barber C (1986) The prediction of abnormal evoked potentials in schizophrenic patients by means of symptom pattern. Br J Psychol 149:46–50
Andrews HB, Barber C, Cooper JE, Raine A (1987) Early somatosensory evoked potentials in schizophrenia: symptom pattern, clinical outcomes and interhemispheric functioning. In: Takahashi R, Flor-Henry P, Gruzelier J, Niwa SI (eds) Cerebral dynamics, laterality and psychopathology. Elsevier, Amsterdam, pp 175–186
Annett M (1970) Classification of hand preference by association analysis. Br J Psychol 61:303–321
Bleuler E (1950) Dementia praecox or the group of schizophrenias. New York International University Press, New York (translated from 1911 original)
Bragina NN (1966) Clinical syndromes of disorders of the hippocampus and adjacent areas of the brain. Klin Med (Mosk) 44:23–27
Buchsbaum MS, King AC, Cappelletti J, Coppola R, van Kammen DP (1982) Visual evoked potential topography in patients with schizophrenia and normal controls. Adv Biol Psychiatry 9:50–56
Bull HC, Venables PH (1974) Speech perception in schizophrenia. Br J Psychiatry 125:350–354
Cohen G (1982) Theoretical interpretations of lateral asymmetries. In: Beaumont JG (ed) Divided visual field studies of cerebral organisation. Academic, New York, pp 87–115
Connolly JF, Gruzelier JH (1982) A critical examination of augmenting/reducing methodology in schizophrenic patients and controls. In: Langnau ED (ed) Advances in biological psychiatry, vol 9. Karger, Basel
Crow TJ (1980) Molecular pathology of schizophrenia: more than one disease process? Br Med J 280:66–68
Cummings JL, Benson DF (1984) Subcortical dementia: review of an emerging concept. Arch Neurol 41:874–879
Davison K, Bagley CR (1969) Schizophrenia-like psychoses associated with organic disorders of the central nervous system: a review of the literature. In: Herrington RN (ed) Current problems in neuropsychiatry. Royal Medico-Psychological Association, London
Dimond SJ, Beaumont JG (1973) Difference in vigilance performance of the right and left hemisphere. Cortex 9:259–265
Flor-Henry P (1969) Psychosis and temporal lobe epilepsy: a controlled investigation. Epilepsia 10:363–395
Flor-Henry P (1974) Psychosis, neurosis and epilepsy. Br J Psychiatry 124:144–150
Flor-Henry P (1983) Cerebral basis of psychopathology. Wright, New York
Flor-Henry P, Yeudal LG (1979) Neuropsychological investigation of schizophrenia and manic-depressive psychoses. In: Gruzelier J, Flor-Henry P (eds) Hemisphere asymmetry of function and psychopathology. Elsevier/North Holland Biomedical, Amsterdam, pp 341–362
Franzen G, Ingvar DH (1975) Abnormal distribution of cerebral activity in chronic schizophrenia. J Psychiatr Res 12:199–214
Friedman D (1987) The endogenous scalp-recorded brain potentials in schizophrenia. In: Stein-hauer S, Gruzelier JH, Zubin J (eds) Experimental psychopathology, neuropsychology & psychophysiology. Elsevier Science, Amsterdam (Handbook of schizophrenia, vol 4
Gaebel W, Ulrich G, Frick K (1986) Eye-movement research with schizophrenic patients and normal controls using corneal reflection-pupil centre measurement. Eur Arch Psychiatry Neurol Sci 235:243–254
Gibbs FA, Gibbs EL (1961) Clinical and pharmacological correlates of fast activity in electroencephalography. J Neuropsychiatry 3:73–78
Gruzelier JH (1973) Bilateral asymmetry of skin conductance orienting activity and levels with schizophrenics. Biol Psychol 1:21–41
Gruzelier JH (1983) A critical assessment and integration of lateral asymmetries in schizophrenia. In: Myslobodsky MS (ed) Hemisyndromes, psychobiology, neurology and psychiatry. Academic, New York, pp 265–326
Gruzelier JH (1984) Hemispheric imbalances in schizophrenia. Int J Psychophysiol 1:227–240
Gruzelier JH (1987 a) Commentary on neuropsychological information processing deficits in psychosis and neuropsychophysiological syndrome relationships in schizophrenia. In: Taka-hashi R, Flor-Henry P, Gruzelier J, Niwa S (eds) Cerebral dynamics, laterality and psycho-pathology. Elsevier Science, Amsterdam, pp 23–54
Gruzelier JH (1987) Cerebral laterality in schizophrenia: a review of the interhemispheric disconnection hypothesis. In: Glass A (ed) Individual differences in hemispheric specialisation. Plenum, London, pp 357–376
Gruzelier JH (1987) Individual differences in dynamic process asymmetries in the normal and pathological brain. In: Glass A (ed) Individual differences in hemispheric specialisation. Plenum, London, 301–330
Gruzelier JH, Manchanda R (1982) The syndrome of schizophrenia: relations between electro-dermal response, lateral asymmetries and clinical subtypes. Br J Psychiatry 141:488–495
Gruzelier JH, Venables PH (1972) Skin conductance orienting activity in a heterogeneous sample of schizophrenics: possible evidence of limbic dysfunction. J Nervous Ment Dis 155:277–287
Gruzelier JH, Venables PH (1973) Skin conductance responses to tones with and without attentional significance in schizophrenic and non-schizophrenic patients. Neuropsychologia 11:221–230
Gruzelier JH, Venables PH (1974) Bimodality and lateral asymmetry of skin conductance orienting activity in schizophrenics: replication and evidence of lateral asymmetry in patients with depression and disorders of personality. Biol Psychiatry 8:55–73
Gruzelier J, Wilson L (1987) The hemisphere imbalance syndrome rating scale (in preparation)
Gruzelier JH, Jutai J, Connolly JF, Hirsch SR (1985) Cerebral asymmetries in unmedicated schizophrenic patients in EEG spectra and their relation to clinical and autonomic parameters. Adv Biol Psychiatry 15:12–19
Gruzelier J, Seymour K, Wilson L, Jolley A, Hirsch S (1987) Neuropsychological evidence for hippocampal and frontal impairments in schizophrenia, mania and depression. In: Takahashi R, Flor-Henry P, Gruzelier J, Niwa S (eds) Cerebral dynamics, laterality and psychopathology. Elsevier Science, Amsterdam, pp 273–286
Günther W, Breitling D (1985) Predominant sensorimotor area left hemisphere dysfunction in schizophrenia measured by brain electrical activity mapping. Biol Psychiatry 20:515–532
Günther W, Breitling D, Banquet JP, Marcie P, Rondot P (1986) EEG mapping of left hemisphere dysfunction during motor performance in schizophrenia. Biol Psychiatry 21:249–262
Gur RE, Skolnik BE, Gur RC et al (1983) Brain function in psychiatric disorders. Arch Gen Psychiatry 40:1250–1254
Ingvar DH, Franzen G (1974) Abnormalities of cerebral bloodflow distribution in patients with chronic schizophrenia. Acta Psychiatr Scand 50:425–462
Johnstone EC, Crow TJ, Frith CD, Husband J, Kreell (1978) The dementia of dementia praecox. Acta Psychiatr Scand 57:305–324
Jutai J, Gruzelier JH, Connolly J, Manchanda R, Hirsch SR (1984) Schizophrenia ad spectral analysis of the visual evoked potential. Br J Psychiatry 145:496–501
Karson CN, Coppola R, Morihisa JM, Weinberger DR (1987) Computed electroencephalo-graphic activity mapping in schizophrenia. Arch Gen Psychiatry 44:514–517
Kaufman L, Williamson SJ (1982) Magnetic location of cortical activity. Ann Ny Acad Sci 388:197–213
Kety SS (1980) The syndrome of schizophrenia: unresolved questions and opportunities for research. Br J Psychiatry 136:421–436
Kinsbourne M (1982) Hemispheric specialisation and the growth of human understanding. Am Psychol 37:411–420
Kolb B, Whishaw I (1983) Performance of schizophrenic patients on tests sensitive to left or right frontal, temporal or parietal function in neurological patients. J Nerv Ment Dis 171:435–443
Kraepelin EE (1896) Lehrbuch der Psychiatric Barth, Leipzig
Malamud N (1967) Psychiatric disorders with intracranial tumours of the limbic system. Arch Neurol 17:113–123
Matthyssee S, Spring BG, Sugarman J (eds) (1978) Attention and information processing in schizophrenia. J Psychiatr Res 14:133
Mesulam M (1981) A cortical network for directed attention and unilateral neglect. Ann Neurol 10:309–325
Mesulam MM, Geschwind N (1978) On the possible role of neocortex and its limbic connections in the process of attention and schizophrenia. J Psychiatr Res 14:249–260
Milner B (1971) Interhemispheric differences in the localisation of psychological processes in man. Br Med Bull 27:272–277
Morihisa JM, Duffy FH, Wyatt RJ (1983) Brain electrical activity mapping (BEAM) in schizophrenic patients. Arch Gen Psychiatry 40:719–728
Morstyn R, Duffy FH, McCarley RW (1983) Computed P300 topography in schizophrenia. Electroencephalogr Clin Neurophysiol 40:729–734
Newlin DB, Carpenter B, Golden J (1981) Hemispheric asymmetries in schizophrenia. Biol Psychiatry 16:561–582
Petsche H, Pockberger H, Rappelsberger P (1985) EEG topography and mental performance. In: Duffy FH (ed) Topographic mapping of brain electrical activity. Butterworth, London
Petrides M (1985) Deficits on conditional associative-learning tasks after frontal lobe and temporal lobe lesions in man. Neuropsychologia 23:601–614
Pribram KH, McGuinness D (1975) Arousal, activation and effort in the control of attention. Psychol Rev 82:116–147
Reynolds GP (1983) Increased concentrations and lateral asymmetry of amygdala dopamine in schizophrenics. Nature 305:527–529
Reynolds GP, Czudek C (1987) Neurochemical laterality of the limbic system in schizophrenia. In: Takahashi R, Flor-Henry P, Gruzelier J, Niwa S (eds) Cerebral dynamics, laterality and psychopathology. Elsevier Science, Amsterdam, pp 451–456
Rosenthal R, Bigelow LB (1972) Quantitative brain measurements in chronic schizophrenia. Br J Psychiatry 121:259–264
Sackheim HA, Greenberg MS, Wynman AL et al (1982) Hemispheric asymmetry in the expression of positive and negative emotions: neurological evidence. Arch Neurol 39:210–218
Shagass C (1977) Early evoked potentials. Schizophr Bull 3:80–92
Sheppard G, Gruzelier JH, Manchanda R, Hirsch SR, Wise R, Frackowiak R, Jones T (1983) 15–0 positron emission tomographic scanning in predominantly never-treated acute schizophrenic patients. The Lancet 2:1448–1452
Smythies JR (1969) The behavioural physiology of the temporal lobe. In: Herrington RN (ed) Current problems in neuropsychiatry. Royal Medico-Psychological Association, London
Torrey EF, Peterson MR (1974) Schizophrenia and the limbic system. Lancet 2:942–946
Tucker DM, Williamson PA (1984) Asymmetric neural control systems in human self-regulation. Psychol Rev 91:185–215
Venables PH (1964) Input dysfunction in schizophrenia. In: Mahar B (ed) Advances in experimental personality research, vol 1. Academic, New York
Walker E, McGuire S (1982) Intra- and inter-hemispheric information processing in schizophrenia. Psychol Bull 92:701–725
Warrington EK (1984) Recognition memory test manual. NFER-Nelson, Windsor
Weinberger DR, Burman KF, Zee RF (1986) Physiologic dysfunction of dorso-lateral prefrontal cortex in schizophrenia. I. Regional cerebral bloodflow evidence. Arch Gen Psychiatry 43:114–124
Wexler BE (1980) Cerebral laterality and psychiatry: a review of the literature. Am J Psychiatry 137:279–291
Wing JK, Cooper JE, Sartorius N (1974) The measurement and classification of psychiatric symptoms. Cambridge University Press, London
Wood CC, Allison T, Goff WR (1980) On the neural origin of P300 in man. Prog Brain Res 54:51–56
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Gruzelier, J., Liddiard, D. (1989). The Neuropsychology of Schizophrenia in the Context of Topographical Mapping of Electrocortical Activity. In: Maurer, K. (eds) Topographic Brain Mapping of EEG and Evoked Potentials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72658-3_48
Download citation
DOI: https://doi.org/10.1007/978-3-642-72658-3_48
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-72660-6
Online ISBN: 978-3-642-72658-3
eBook Packages: Springer Book Archive