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Abnormal Marker Expression in Acute Leukemia (AL) Characterized by Monoclonal Antibodies and Flow Cytometry

  • Conference paper
Acute Leukemias

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 30))

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Abstract

The application of refined immunologic and enzymatic markers to conventional morphologic and cytochemical techniques has revealed an unexpected heterogeneitiy in acute leukemia (AL). Since the development of monoclonal antibodies (MoAbs) to lineage specific differentiation markers, there have been several reports of AL patients whose blast cells represent relatively homogeneous populations with phenotypic features of more than one cell line [1–5] or are characterized by the coexistence of separate cell populations each demonstrating either lymphoid or myeloid features [6–10].

Supported in part by the Deutsche Krebshilfe.

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Author information

Authors and Affiliations

  1. Department of Hematology and Oncology, Klinikum Steglitz, Berlin, Germany

    W. D. Ludwig, H. Seibt, B. Komischke & H. Rühl

  2. Department of Internal Medicine, University of Münster, Germany

    W. Hiddemann

  3. Department of Hematology, University of Mainz, Federal Republic of Germany

    F. Herrmann

Authors
  1. W. D. Ludwig
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  2. W. Hiddemann
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  3. F. Herrmann
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  4. H. Seibt
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  5. B. Komischke
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  6. H. Rühl
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Editor information

Editors and Affiliations

  1. Departments of Internal Medicine and Pediatrics, University of Münster, Albert-Schweitzer-Strasse 33, D-4400, Münster, Federal Republic of Germany

    T. Büchner , G. Schellong , W. Hiddemann , D. Urbanitz  & J. Ritter , , ,  & 

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© 1987 Springer-Verlag Berlin Heidelberg

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Ludwig, W.D., Hiddemann, W., Herrmann, F., Seibt, H., Komischke, B., Rühl, H. (1987). Abnormal Marker Expression in Acute Leukemia (AL) Characterized by Monoclonal Antibodies and Flow Cytometry. In: Büchner, T., Schellong, G., Hiddemann, W., Urbanitz, D., Ritter, J. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71213-5_39

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  • DOI: https://doi.org/10.1007/978-3-642-71213-5_39

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16556-9

  • Online ISBN: 978-3-642-71213-5

  • eBook Packages: Springer Book Archive

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