Abstract
Alpha-1-antitrypsin (α1AT) is an important protease inhibitor (PI) capable of inhibiting a wide variety of serine proteases. Since the first description of genetic variation in 1963 (1) more than 60 genetic variants of this protease inhibitor have been observed (2). For classification of PI variants isoelectric focusing (IEF) has been employed since ten years. IEF has been particularly useful in identifying subtypes of the most common variant PI M (3–9).
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© 1986 Springer-Verlag Berlin Heidelberg
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Weidinger, S., Schwarzfischer, F. (1986). PI M5: An Additional Alpha-1-Antitrypsin PI M Subtype Revealed by IEF with Immobilized Ph Gradients. In: Brinkmann, B., Henningsen, K. (eds) 11th Congress of the Society for Forensic Haemogenetics (Gesellschaft für forensische Blutgruppenkunde e.V.). Advances in Forensic Haemogenetics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71150-3_19
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DOI: https://doi.org/10.1007/978-3-642-71150-3_19
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