Skip to main content

Effects of Anaesthesia on Haemodynamic Responses to Haemorrhage

  • Chapter
Mortality in Anaesthesia

Part of the book series: European Academy of Anaesthesiology ((ANAESTHESIOLOGY,volume 3))

  • 79 Accesses

Abstract

The traditional concepts of haemodynamic responses to harmorrhage have been derived primarily from studies in anaesthetized animals, often by using indirect techniques for measuring blood flow. It is, however, well recognized that general anaesthetic agents exert a variety of influences on the cardiovascular system and its control by the autonomic nervous system(1–6). Moreover, the effects of the anaesthetic agents can be modified further by concomitant surgical trauma(7).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Vatner SF (1978) Effects of anesthesia on cardiovascular control mechanisms. Environ Health Perspect 26: 193

    Article  PubMed  CAS  Google Scholar 

  2. Merin RG, Kumazawa T and Luka NL (1976) Enflurane depresses myocardial function, perfusion and metabolism in the dog. Anesthesiology 45: 501

    Article  PubMed  CAS  Google Scholar 

  3. Horan BF, Prys-Roberts C, Hamilton WK and Roberts JG (1977) Haemodynamic responses to enflurane anesthesia and hypovolaemia in the dog, and their modification by propranolol. Br J Anaesth 49: 1189

    Article  PubMed  CAS  Google Scholar 

  4. Zimpfer M, Gilly H, Krosl P, Schlag G and Steinbereithner K (in press) Importance of myocardial loading conditions in determining the effects of enflurane on left ventricular function in the intact and isolated canine heart. Anesthesiology

    Google Scholar 

  5. Beck A, Zimpfer M, Raberger G (in press) Inhibition of the carotid chemoreflex by enflurane in chronically instrumented dogs. Naunyn-Schmied Arch Pharmacol

    Google Scholar 

  6. Zimpfer M, Manders WT, Barger AC, Vatner SF (in press) Pentobarbital alters compensatory neural and humoral mechanisms in response to haemorrhage. Am J Physiol

    Google Scholar 

  7. Fray JCW, Siwek LG, Strull WM, Steller RN and Wilson JM (1976) Influence of dietary sodium on renin activity and arterial pressure during anesthesia. Am J Physiol 231: 1185

    PubMed  CAS  Google Scholar 

  8. Armitage P (1971) Statistical methods in medical research. Oxford, Blackwell Sci-entific Publications

    Google Scholar 

  9. Chien S (1967) Role of the sympathetic nervous system in haemorrhage. Physiol Ref 47: 214

    CAS  Google Scholar 

  10. Haddy FJ, Overbeck HW, Daugherty RM Jr (1968) Peripheral Vascular resistance. Ann Rev Med 19: 167

    Article  PubMed  CAS  Google Scholar 

  11. Guyton AC (1976) Textbook of medical physiology. Philadelphia London Toronto, WB Saunders

    Google Scholar 

  12. Morton M, Duke PC and Ong B (1980) Baroreflex control of heart rate in man awake and during enflurane and enflurane-nitrous oxide anesthesia. Anesthesiology 52: 221

    Article  PubMed  CAS  Google Scholar 

  13. Weiskopf RB, Townsley MI, Riordan KK, Chadwick K, Baysinger M and Mahoney E (1981) Comparison of cardiopulmonary responses to graded haemorrhage during enflurane, halothane, isoflurane, and ketamine anesthesia. Anaesth Analg 60: 481

    Article  CAS  Google Scholar 

  14. Schumacher IG and Arndt JO (1978) Der Effekt von Methohexital, Fentanyl, De- hydrobenzperidol sowie von Chloralone auf die Aktivitat des Aortenbogens decere- brierter Katzen. Anaesthetist 27: 10

    CAS  Google Scholar 

  15. Zimpfer M, Beck A, Mayer N, Raberger G and Steinbereithner K (in press) Einfluft von Morphium auf die Kontrolle des kardiovaskularen Systems durch den Carotis- Sinus-Reflex und den Carotis-Chemoreflex. Anaesthesist

    Google Scholar 

  16. Marta JA, Davis HS and Eisele JH (1973) Vagomimetic effects of morphine and In- novar in man. Anaesth Analg 52: 817

    Article  CAS  Google Scholar 

  17. Hug CC Jr (1982) Anesthetic agents and the patient with cardiovascular disease. In: Ream AK, Fogdall RP (eds) Acute cardiovascular management. Philadelphia Toronto, J.B. Lippincott, p 247

    Google Scholar 

  18. Eger II EI (1976) Anesthetic uptake and action. Baltimore, Williams and Wilkins

    Google Scholar 

  19. Biscoe TJ, Bardley GW and Purves MJ (1970) The relation between carotid body chemoreceptor discharge, carotid sinus pressure, and carotid body venous flow. J Physiol 208: 99

    PubMed  CAS  Google Scholar 

  20. Zimpfer M, Beck A, Raberger G, Mayer N and Steinbereithner K (1982) Effects of fentanyl on the carotid chemoreflex. Anesthesiology 57: A296

    Article  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Zimpfer, M., Kotae, E., Mayer, N., Placheta, P., Steinbereithner, K. (1983). Effects of Anaesthesia on Haemodynamic Responses to Haemorrhage. In: Vickers, M.D., Lunn, J.N. (eds) Mortality in Anaesthesia. European Academy of Anaesthesiology, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69355-7_28

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69355-7_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-12824-3

  • Online ISBN: 978-3-642-69355-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics