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Cholinergics

  • Chapter
Pharmacology of the Eye

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 69))

Abstract

Cholinergic drugs can exert biological activity by modifying the normal mechanism of ACh-mediated autonomic neurotransmission in several ways (Fig. 1; Koelle 1975 a): interference with transmitter synthesis (hemicholinium); prevention of transmitter release (botulinum toxin); displacement of transmitter from ax-onal terminal (carbachol); mimicry of transmitter at postsynaptic receptor (methacholine, carbachol, nicotine); blockade of transmiter at postsynaptic receptor (atropine, D-tubocurarine, hexamethonium); inhibition of enzymatic breakdown of transmitter (anticholinesterases).

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Authors
  1. P. L. Kaufman
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  2. T. Wiedman
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  3. J. R. Robinson
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Editor information

Editors and Affiliations

  1. Department of Ophthalmology and Visual Science, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06510, USA

    Marvin L. Sears

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© 1984 Springer-Verlag Berlin Heidelberg

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Kaufman, P.L., Wiedman, T., Robinson, J.R. (1984). Cholinergics. In: Sears, M.L. (eds) Pharmacology of the Eye. Handbook of Experimental Pharmacology, vol 69. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69222-2_4

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  • DOI: https://doi.org/10.1007/978-3-642-69222-2_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69224-6

  • Online ISBN: 978-3-642-69222-2

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