Abstract
Effective research in brain edema requires a reliable method for the determination of brain water content. The gravimetric technique has apparent advantages over the conventional drying-weighing method, especially in the determination of brain water in small samples of brain. The value of specific gravity (SG) is not a direct measure of water, and some of the factors that affect SG, such as the composition of edema (4) and the cerebral blood volume (CBV) (1) have recently been analysed. In addition, fundamental technical considerations such as linearity of the gradient column and optimisation of measuring conditions must first be satisfied. After establishing the technical bases in this study, the effect of CBV on SG has been investigated. In comparison with the gravimetric technique, the drying-weighing method has further been analysed, yielding a different nature of error factors in both methods.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ferszt R, Hahm H, Cervos-Navarro (1980) Measurement of the specific gravity of the brain as a tool in brain edema research. Adv Neurol 28:15–26
Gazendam J, Go KG, van Zanten AK (1979) Composition of isolated edema fluid in cold-induced brain edema. J Neurosurg 51:70–77
Hahm H (1980) Die mikrogravimetrische Quantifizierung des hyposmolaren Hirnödems. Berlin: University Press of Freie Universität Berlin, p 1ll
Marmarou A, Tanaka K, Shulman K (1982) An improved gravimetric measure of cerebral edema. J Neurosurg 52:246–253
Shigeno T, Aritake K, Saito I, Sano K (1980) Hydrocephalus following early operation on ruptured cerebral aneurysm: Significance of long-term monitoring of intracranial pressure. In: Shulman K, Marmarou A, Miller JD, Becker DP, Hochwald GH, Brock M (eds) Intracranial Pressure IV. Springer, Berlin Heidelberg New York, p 235–240
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Shigeno, S., Shigeno, T., Brock, M., Fritschka, E., Cervos-Navarro, J. (1983). Comparative Reassessment of the Gravimetric and the Drying-Weighing Methods. In: Ishii, S., Nagai, H., Brock, M. (eds) Intracranial Pressure V. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69204-8_63
Download citation
DOI: https://doi.org/10.1007/978-3-642-69204-8_63
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-69206-2
Online ISBN: 978-3-642-69204-8
eBook Packages: Springer Book Archive