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The Importance of Electrolyte Shifts and Calcium Binding on Cardiotoxicity of Contrast Media

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Book cover Contrast Media in Radiology

Abstract

The summary of our experimental and clinical examinations on cardiac side effects of coronary angiography is that the acute phenomena are mainly caused by physicochemi-cal properties of the contrast media [1, 2]. This seems to be true in case of the well-known hemodynamic side effects: acute cardiodepression followed by a delayed positive inotropic effect and long-lasting increase of coronary blood flow combined with reduction of coronary vascular resistance and increase of coronary venous O2-saturation. The same properties seem to be responsible for the typical electrocardiographic effects: hypervoltage combined with shift of the electrical axis of the heart, disturbance of electrical activation- and repolarization waves and dysrhythmias.

Supported by the Deutsche Forschungsgemeinschaft, SFB 89 — Kardiologie Göttingen

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References

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© 1982 Springer-Verlag Berlin Heidelberg

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Hellige, G., Baller, D., Hoeft, A., Korb, H., Wolpers, H.G., Zipfel, J. (1982). The Importance of Electrolyte Shifts and Calcium Binding on Cardiotoxicity of Contrast Media. In: Amiel, M. (eds) Contrast Media in Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68584-2_18

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  • DOI: https://doi.org/10.1007/978-3-642-68584-2_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-11534-2

  • Online ISBN: 978-3-642-68584-2

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