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Amines: Histamine

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Mediators and Drugs in Gastrointestinal Motility II

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 59 / 2))

Abstract

Physiologic roles of histamine have not yet been clarified. Its distribution in the gastrointestinal tract is consistent with the idea that it has a function in secretion rather than in motility, but there are many important factors which cannot be disregarded: the turnover rate of histamine, the number and susceptibility of receptors at the specific targets, the interaction with other humoral and nervous mediators, etc. Of course, detailed consideration of histamine distribution, synthesis, and metabolism is beyond the scope of this review.

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  1. G. Bertaccini
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Editors and Affiliations

  1. School of Medicine, University of Parma, I-43100, Parma, Italy

    Giulio Bertaccini M.D. (Head of the Department of Pharmacology) (Head of the Department of Pharmacology)

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Bertaccini, G. (1982). Amines: Histamine. In: Bertaccini, G. (eds) Mediators and Drugs in Gastrointestinal Motility II. Handbook of Experimental Pharmacology, vol 59 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68474-6_7

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  • DOI: https://doi.org/10.1007/978-3-642-68474-6_7

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