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Effect of Insulin on the Biliary Excretion of Some Organic Anions in Rats

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Further Studies in the Assessment of Toxic Actions

Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 4))

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Abstract

In rats insulin enhanced the biliary excretion of rose bengal (50 mg/kg) and bromcresol green (25 mg/kg), and raised the depressed bile flow caused by these organic anions. There was, however, no parallelism between the choleretic effect of insulin and the increase in biliary transport of the two dyes.

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References

  • Fischer, E., Varga, F., Gregus, Z., Gógl, Á.: Bile flow and biliary excretion of some organic anions in phenobarbital-pretreated rats. Digestion 17, 211–220 (1978)

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  • Fritz, M. E., Brooks, F. P.: Control of bile flow in the cholecystectomized dog. Am. J. Physiol. 204, 825–828 (1963)

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  • Varga, F., Fischer, E.: Biliary secretion of rose bengal in the dog. Acta physiol. Acad. Sci. hung. 38, 143–149 (1970)

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© 1980 Springer-Verlag

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Varga, F., Málly, J., Fischer, E. (1980). Effect of Insulin on the Biliary Excretion of Some Organic Anions in Rats. In: Chambers, P.L., Klinger, W. (eds) Further Studies in the Assessment of Toxic Actions. Archives of Toxicology, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67729-8_86

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  • DOI: https://doi.org/10.1007/978-3-642-67729-8_86

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10191-8

  • Online ISBN: 978-3-642-67729-8

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