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Possible Role of the Friend Virus Life Cycle in Differentiating Friend Leukemia Cells Treated with Interferon

  • Conference paper
Modern Trends in Human Leukemia III

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 23))

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Abstract

Friend erythroleukemia cells (FLC) are proerythroblasts chronically infected with the Friend virus complex (FLV, composed by LLV and SFFV). They undergo erythroid differentiation accompanied by synthesis of heme and hemoglobin (Hb), accumulation of globin mRNA and erythrocyte-specific membrane changes upon treatment with DMSO and other polar solvents [6].

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References

  1. Cioé, L., Dolei, A., Rossi, G.B., Belardelli, F., Affabris, E., Gambari, R., Fantoni, A.: Potential for differentiation, virus production, and tumorigenicity in murine erythroleukemic cells treated with interferon. In: In vitro aspects of erythropoiesis. Murphy, M. (ed.), pp. 159–171. Berlin, Heidelberg, New York: Springer 1978

    Google Scholar 

  2. Colletta, G., Fragomele, F., Sandomenico, M. L., Vecchio, G.: Induction of viral polypeptides and messenger RNA by dimethyl sulfoxide and bromodeoxyuridine in Friend erythroleukemic cells. (Manuscript in preparation)

    Google Scholar 

  3. Dolei, A., Capobianchi, M.R., Cioé, L., Colletta, G., Vecchio, G., Rossi, G.B., Affabris, E., Belardelli, F.: Effects of interferon on the expression of cellular and integrated viral genes in Friend erythroleukemic cells. In: Antiviral mechanisms in the control of neoplasia. Chandra. P. (ed.). New York (in the press)

    Google Scholar 

  4. Friedman, R. M.: Antiviral activity of interferons. Bact. Rev. 41, 543–567 (1977)

    PubMed  CAS  Google Scholar 

  5. Friend, C., Sher, W., Tsuei, D., Haddad, J., Holland, J.G., Szrajer, N., Haubenstock, H.: In: Oncogenic viruses and host genes. Ikawa, Y. (ed.). New York: Academic Press 1977 (in the press)

    Google Scholar 

  6. Harrison, P. R.: The biology of Friend cells. In: Biochemistry of differentiation. Paul, J. (ed.), pp. 227–267. London: MTP Publish 1977

    Google Scholar 

  7. Lockart, R.Z. Jr.: Criteria for acceptance of a viral inhibitor as an interferon and a general description of the biological properties of known interferons. In: Interferons and interferon inducers. Finter, N. B. (ed.), pp. 11–27. Amsterdam: North-Holland Publ. 1973

    Google Scholar 

  8. Lunadei, M., Matteucci, P., Ullu, E., Gambari, R., Rossi, G.B., Fantoni, A.: Disappearance of a 32.000 D. chromatin polypeptide during early erythroid differentiation of Friend leukemia cells. Exp. Cell. Res. 114, 1978 (in press)

    Google Scholar 

  9. Matarese, G. P., Rossi, G. B.: Effect of interferon on growth and division cycle of Friend erythroleukemic murine cells in vitro. J. Cell. Biol. 75, 344–355 (1978)

    Article  Google Scholar 

  10. Ostertag, W., Pragnell, J. B., Swetly, P., Arnolt-Jovin, D., Krieg, C., Clauss, V: abstract. Symposium on interferons and the control of cell-virus interactions. May 2–6, Rehovot, Israel 1977

    Google Scholar 

  11. Rossi, G.B., Matarese, G.P., Grappelli, C., Belardelli, F., Benedetto, A.: Interferon inhibits dimethyl sulfoxide-induced erythroid-differentiation in Friend leukemia cells. Nature 267, 50–52 (1977)

    Article  PubMed  CAS  Google Scholar 

  12. Rossi, G.B., Dolei, A., Cioé, L., Benedetto, A., Matarese, G.P., Belardelli, F.: Inhibition of transcription and translation of globin messenger RNA in dimethyl sulfoxide-stimulated Friend erythroleukemic cells treated with interferon. Proc. Natl. Acad. Sci. USA 74, 2036 to 2040 (1977)

    Article  PubMed  CAS  Google Scholar 

  13. Rossi, G. B., Aducci, P., Gambari, R., Minetti, M., Vernole, P.: Presence of spectrin in untreated Friend erythroleukemia cells, J. Cell. Phys. (1978) (in press)

    Google Scholar 

  14. Troxler, D., Scolnick, E. M.: Rapid leukemia induced by cloned strains of replicating murine type-C virus. Association with induction of xenotropic-related RNA sequences. Virology 85, 1727–1730 (1978)

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Istituto di Virologia, University of Rome, Rome, Italy

    A. Dolei, M. R. Capobianchi & L. Cioé

  2. Centro di Endocrinologia e Oncologia Sperimentale del CNR, II Facoltà di Medicina, University of Naples, Naples, Italy

    G. Colletta (Cattedra di Virologia Oncologica) & G. Vecchio (Cattedra di Virologia Oncologica)

  3. University of Rome, Rome, Italy

    G. B. Rossi (Cattedra di Microbiologia), E. Affabris (Cattedra di Microbiologia) & F. Belardelli (Cattedra di Microbiologia)

  4. Istituto Superiore di Sanità, Rome, Italy

    G. B. Rossi (Cattedra di Microbiologia), E. Affabris (Cattedra di Microbiologia) & F. Belardelli (Cattedra di Microbiologia)

Authors
  1. A. Dolei
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  2. M. R. Capobianchi
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  3. L. Cioé
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  4. G. Colletta
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  5. G. Vecchio
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  6. G. B. Rossi
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  7. E. Affabris
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  8. F. Belardelli
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Editor information

Editors and Affiliations

  1. Molekularbiologisch-hämatologische Arbeitsgruppe, Universitäts-Kinderklinik, Martinistraße 52, D-2000, Hamburg 20, Federal Republic of Germany

    Rolf Neth

  2. Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014, USA

    Robert C. Gallo

  3. Max-Planck-Institut für Biochemie, D-8033, Martinsried bei München, Federal Republic of Germany

    Peter-Hans Hofschneider

  4. Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie, Universität Hamburg, Martinistraße 52, D-2000, Hamburg 20, Federal Republic of Germany

    Klaus Mannweiler

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© 1979 Springer-Verlag Berlin Heidelberg

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Dolei, A. et al. (1979). Possible Role of the Friend Virus Life Cycle in Differentiating Friend Leukemia Cells Treated with Interferon. In: Neth, R., Gallo, R.C., Hofschneider, PH., Mannweiler, K. (eds) Modern Trends in Human Leukemia III. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 23. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67057-2_39

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  • DOI: https://doi.org/10.1007/978-3-642-67057-2_39

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08999-5

  • Online ISBN: 978-3-642-67057-2

  • eBook Packages: Springer Book Archive

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