Zusammenfassung
Die Salze des Kations Lithium sind wegen ihrer besonderen physikalischen Eigenschaften in der klinischen Medizin schon relativ früh mit therapeutischer Absicht verwandt worden. Als erster versuchte Garrod (1859) die Gicht mit Lithium zu behandeln, weil Lithiumurat löslicher ist, als Kalium- und Natriumurat. Der Versuch schlug u.a. fehl wegen des ubiquitären Vorkommens von Na+ und K+ in allen Körperflüssigkeiten. Später hat man Lithiumsalze wegen ihres Geschmacks als Natriumersatz in kochsalzarmen Diäten anzuwenden versucht. Seit 1949 wird Lithium nach einer Erstbeschreibung von Cade als psychoaktives Agens bei Manien eingesetzt. Das Ergebnis war, daß Lithium heute einmal als gesichertes Therapeuticum und Prophylakticum zur Beeinflussung der manischen Depressionen gilt und daß man zum anderen z.T. Lithiumintoxikationen mit fatalem Ausgang beobachtete (Literatur und zusammenfassende Übersicht: Johnson, F.N., Lithium Research and Therapy. New York-London: Academic Press 1975).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Abuzzahab, F.S.: The effect of lithium carbonate on the thyroid function. Fed. Proc. 28, 260(1969).
Allsopp, M.N.E., Level, M.J., Stich, S.R., Hullin, R.P.: Aldosterone production rates in manic-depressive psychosis. Brit. J. Psychiat. 120, 399 (1972).
Altamura, A.C., Morganti, A.: Plasma Renin activity in depressed patients treated with increasing dosis of lithium carbonate. Psychopharmacologia 45, 171 (1975).
Amdisen, A.: Development of goiter during lithium treatment. Ugeskr. Laeg 130, 1515 (1968).
Anderson, D.K., Prockop, L.D.: Lithium absorption and distribution in body tissues. In: Lithium Research and Therapie (Ed. F.N. Johnson). New York-London: Academic Press 1975.
Andreoli, V.M., Villani, F., Brambilla, G.: Increased calcium and magnesium excretion induced by lithium carbonat. Psychopharmacologia 25, 77 (1972).
Angrist, B.M., Gershon, S., Levitan, J., Blumberg, A.G.: Lithium-induced diabetes insipidus-like syndrome. Comprehens. Psychiat. 11, 141 (1970).
Baer, L., Platman, S.R., Kassi, S., Fieve, R.R.: Mechanisms of renal lithium handling and their relationship to mineralo-corticoids: a dissociation between sodium and lithium ions. J. psychiat. Res. 8, 91 (1971).
Baer, L., Glassman, A.H., Kassi, S.: Negative sodium balance in lithium carbonate toxicity. Evidence of mineralocorticoid blockade. Arch. gen. Psychiat. 29, 823 (1973).
Bafaqeeh, H.H., Myers, D.H.: Lithium and thyrotoxicosis. Lancet 19761, 1409.
Bakker, K.: Lithium and thyrotoxicosis. Lancet 19761, 1135.
Balan, G., Cernatescu, D., Trandafirescu, M., Ababai, L.: Lithium action on the activity of hexokinase and pyruvate-kinase. Abstract, 7th Congress CINP, Prague 1970.
Baldessarini, R J., Yorke, C.: Effect of lithium and of pH on synaptosomal metabolism of noradrenaline. Nature 228, 1301 (1970).
Bartter, F.C., Schwartz, W.B.: The syndrome of inappropriate secretion of antidiuretic hormone. Amer. J. Med. 42, 790 (1967).
Basuray, B.N.: Effects of lithium chloride on cardiovascular responses induced by cholinergic and adrenergic stimulations. Europ. J. Pharmacol. 28, 387 (1974).
Beck, N.P., Reed, S.W., Davis, B.B.: Effect of lithium on renal concentration of cyclic AMP. Clin. Res. 19, 684 (1971).
Beck, N., Kim, K.S.: Effect of lithium on catecholamine induced antidiuresis and cAMP in dog kidneys. Endocrinology 96, 744 (1975).
Bennie, E.H., Lazarus, J.H.: Lithium-induced thyroid dysfunction. Lancet 1972 II, 44.
Bentley, P.J., Wasserman, A.: The effect of lithium on the permeability of an epithelial membrane, the toad urinary bladder. Biochim. biophys. Acta (Amst.) 266, 285 (1972).
Berens, S.C., Wolff, J., Murphy, D.L.: Lithium Concentration by the Thyroid. Endocrinology 87, 1085 (1970).
Berens, S.C., Bernstein, R.S., Robbins, J., Wolff, J.: Antithyroid effect of lithium. J. clin. Invest. 49, 1357 (1970b).
Berens, S.C., Williams, J.A., Wolff, J.: Dissociation of thyrotropin glands by lithium. Biochim. biophys. Acta (Amst.) 252, 314 (1971).
Berens, S.C., Wolff, J.: The endocrine effects of lithium. In: Lithium Research and Therapy. (Ed. F.N. Johnson). New York-London: Academic Press 1975.
Bhattacharya, G.: Influence of ions on the uptake of glucose and on the effects of insulin on it by rat diaphragma. Nature 183, 324 (1959).
Bhattacharya, G.: Effect of metal ions on the utilisation of glucose and on the influence of insulin on it by the isolated rat diaphragma. Biochem. J. 79, 369 (1961).
Bhattacharya, G.: Influence of lithium on glucose metabolism in rats and rabbits. Biochim. biophys. Acta (Amst.) 93, 644 (1964).
Bindler, E.H., Wallach, M.B., Gershon, S.: Effect of lithium on the release of 14C-norepi-nephrine by stimulation from perfused cat spleen. Arch. int. Pharmacodyn. 190, 150 (1971).
Birch, N.J., Jenner, F.A.: The distribution of lithium and its effect on the distribution and excretion of other ions in the rat. Brit. J. Pharmacol. 47, 203 (1972).
Birch, N.J.: The role of magnesium and calcium in the pharmacology of lithium. Biol. Psychiat. 7, 269 (1973).
Birnbaumer, L., Pohl, S.L., Rodbell, M.: Adenyl cyclase in fat cells. J. biol. Chem. 244, 3468–3476(1969).
Black, W.J., Van Toi, A., Fernando, J., Horecker, B.L.: Isolation of a highly active fructose diphosphatase from rabbit muscle: its subunit structure and activation by monovalent cations. Arch. Biochem. 151, 576 (1972).
Bliss, E.L., Migeon, C.J., Branch, C.H.: Reaction of the adrenal cortex to emotional stress. Psychosom. Med. 18, 56 (1956).
Bliss, E.L., Alion, J.: The effect of lithium upon brain neuroamines. Brain Res. 24, 305 (1970).
Brain, P.F.: Oral lithium chloride, endocrine function and isolation induced agonistic behaviour in male albino mice. Proc. Soc. Endocrin. 55, 29 (1972).
Briere, J.: The advantage of lithium in association with iodine 131 in the treatment of functioning metastasis of the thyroid cancer. Ann. Endocr. (Paris) 35, 281 (1973).
Bridges, P.K., Jones, M.L.: The diurnal rhythm of plasma Cortisol concentration in depression. Brit. J. Psychiat. 112, 1257 (1966).
Brookbank, B.W., Coppen, A.: Plasma 11-hydroxycorticosteroids in affective disorders. Brit. J. Psychiat. 113, 395 (1967).
Brower, A., Hadley, M.E.: Ionic requirements for melanophor-stimulating hormone (MSH) release. Gen. comp. Endocr. 19, 147 (1972).
Burrow, G.N., Burke, W.R., Himmelhoch, J.M., Spencer, R.P., Hersham, J.M.: Effect of lithium on thyroid function. J. clin. Endocr. 32, 647 (1971).
Bunney, W.E., Davis, J.M.: Norepinephrine in depressive reaction. Arch. gen. Psychiat. 13, 483 (1965).
Bunney, W.E., Mason, J.W., Hamburg, D.A.: Correlations between behavioral variables and urinary 17-hydroxycorticoids in depressed patients. Psychosom. Med. 27, 299 (1965).
Burke, G.: Effect of cations and ouabains on thyroid adenyl cyclase. Biochim. biophys. Acta (Amst.) 220, 30 (1970).
Butler, P.W., Besser, G.M.: Pituitary-adrenal function in severe depressive illness. Lancet 19681, 1234.
Cade, J.F.J.: Lithium salts in the treatment of psychotic excitement. Med. J. 36, 349 (1949).
Candy, J.: Severe hypothyroidism—an early complication of lithium therapy. Brit. med. J. 1972III, 277.
Carlson, H.E., Temple, R., Robbins, J.: Effect of lithium on thyroxine disappearance in man. J. clin. Endocr. 36, 1251 (1973).
Carlson, H.E., Robbins, J., Murphy, D.L.: The effect of lithium on thyroid iodine release in patients with primary affective disorders. Psychopharmacologia 35, 249 (1974).
Carpenter, W.T., Bunney, W.E.: Adrenal cortical activity in depressive illness. Amer. J. Psychiat. 128, 31 (1971).
Christensen, S.: Acute and chronic effects of vasopressin in rats with lithium-polyuria. Acta Pharmacol. (Kbh.) 38, 241 (1976).
Christensson, T.A.T.: Lithium, Hypercalcaemia and Hyperparathyreoidismus. Lancet 1976II, 144.
Clausen, T.: The relationship between the transport of glucose and cations across cell membrans in isolated tissues: The insulin-like effect of lithium. Biochim. biophys. Acta (Amst.) 150, 66 (1968).
Corrodi, H., Fuxe, K., Hokfelt, T., Schou, M.: Effect of lithium on cerebral monoamine neurons. Psychopharmacologia 11, 345 (1967).
Corrodi, H., Fuxe, K., Schou, M.: The effect of prolonged lithium administration on cerebral monoamine neurons in the rat. Life Sci. 8, 643 (1969).
Colburn, R.W., Goodwin, F.K., Bunney, W.E., Davis, J.M.: Effect of lithium on uptake of noradrenaline by synaptosomes. Nature 215, 1395 (1967).
Cooper, T.B., Simpson, G.M.: Preliminary report of a longitudinal study on the effect of lithium on iodine metabolism. Curr. ther. Res. 11, 603 (1969).
Cooper, T.B., Wagner, B.M., Kline, N.S.: Contribution to the mode of action of lithium on iodine metabolism. Biol. Psychiat. 2, 173 (1970).
Cox, M., Singer, I.: Lithium and water metabolism. Amer. J. Med. 59, 153 (1975).
Crowe, M.J., Lloyd, G.G., Bloch, S., Rosser, R.M.: Hypothyroidism in patients treated with lithium: a review and two case reports. Psychol. Med. 3, 337 (1973).
Curbitt, T.: Lithium and thyrotoxicosis. Lancet 19761, 1247.
Davenport, V.D.: Distribution of parenterally administered lithium in plasma, brain and muscle of rats. Amer. J. Physiol. 163, 633 (1950).
Demers, R.G., Hendler, R., Allen, R.P., Boyd, J.: Edema and increased plasma renin activity in lithium treated patients. Behav. Neuropsychiat. 3, 20 (1972).
Depisch, F.: Über eine neue Behandlungsmethode des Diabetes mellitus und verwandter Stoffwechselstörungen. Wien. klin. Wschr. 44, 1216 (1924).
Dry, J.: Occurrence of exophthalmos during treatment with lithium carbonate. Therapie 29, 701 (1974).
Dousa, T., Hechter, O.: The effect of natriumchlorid and lithiumchlorid on vasopressin-sensitive adenyl cyclase. Life Sci. 9, 765 (1970).
Dousa, T.P.: Lithium interaction with ADH dependent cyclic AMP system of human renal medulla. Clin. Res. 21, 282 (1973).
Ebstein, R., Belmaker, R., Grunhaus, L., Rimon, R.: Lithium inhibition of adrenalin-stimulated adenylate cyclase in humans. Nature 259, 410 (1976).
Edhag, O., Swahn, A., Wester, P.O.: Hypothyroidism following lithium treatment. Acta med. scand. 193, 553 (1973).
Eigen, M.: Possible mechanisms of action of lithium from the perspective of “receptor”-lithium interaction. Neuro Sci. Res. Program Bull. 14, 142 (1976).
Eknoyan, G., Corey, G.R., Loomis, J., Suki, W.N., Martinez-Maldonado, M.: Lithium induced diabetes insipidus: effect of urinary cyclic AMP excretion and renal tissue adenylate cyclase activity. Clin. Res. 22, 524 (1974).
Ellman, G.L., Gan, G.L.: Lithium ion and water balance in rats. Toxicol, appl. Pharmacol. 25, 617(1973).
Emerson, C.H., Dyson, W.L., Utiger, R.D.: Serum thyrotropin and thyroxine concentrations in patients receiving lithium carbonate. J. clin. Endoer. 36, 338 (1973).
Fann, W.E., Davis, J.M., Janowsky, D.S., Kaufmann, J.S., Griffith, J.D.: Effect of lithium on adrenergic function in man. J. clin. Pharmacol. 13, 71 (1972).
Fieve, R.R., Platman, S.: Lithium and thyroid function in manic-depressiv psychosis. Amer. J. Psychiat. 125, 527 (1968).
Fieve, R.R., Platman, S.: Follow-up studies of lithium and thyroid function in manicdepressive illness. Amer. J. Psychiat. 125, 1443 (1969).
Fieve, R.R., Baer, L.: Physiological actions of lithium ion. In: Advances in Neurophysico-Pharmacology (Ed. O. Vinar). Amsterdam-London: North Holland Publ. Company 1971.
Fleischer, K., Bini, K.E., Klaus, D., Tölle, R.: Beeinflussung des Plasmarenins und der pressorischen Ansprechbarkeit auf Angiotensinamid durch Lithium beim Menschen. Arzneimittel-Forsch. 21, 1363 (1971).
Fleischman, AJ., Lenz, I.P., Bierenbaum, M.L.: Metabolie Effects of Exogenous Lithium in Rats. Clin. Res. 21, 623 (1973).
Fleischman, A.I., Lenz, P.H., Bierenbaum, M.L.: Effect of lithium upon lipid metabolism in rats. J. Nutr. 104, 1242 (1974).
Forrest, J.N., Cohen, A.D., Torretti, J., Himmelhoch, J.M., Epstein, F.H.: On the mechanism of lithium-induced diabetes insipidus in man and rat. J. clin. Invest. 53, 1115 (1974).
Franklin, L.M.: Thyrotoxicosis developing during lithium treatment. Case report. N.Z. med. J. 79, 782(1974).
Frazer, A., Hancock, A., Mendels, J.: Effect of lithium on catecholamine-induced responses in the isolated perfused Guinea pig heart. Biol. Psychiat. 5, 79 (1972).
Fullerton, D.T., Wenzel, F.J., Lohrenz, F.N.: Circadian rhythm of adrenal Cortisol activity in depression. Arch. gen. Psychiat. 19, 674 (1968).
Fyrö, B., Petterson, U., Sedvall, G.: Time course for the effect of lithium on thyroid function in man and women. Acta psychiat. (Kbh.) 49, 230 (1973).
Fyrö, B., Sedvall, G.: The excretion of lithium. In: Lithium Research and Therapy (Ed. F.N. Johnson). New York-London: Academic Press 1975.
Garfinkel, P.E., Ezrin, C., Stanger, H.C.: Hypothyroidism and hyperparathyroidism associated with lithium. Lancet 1973II, 331.
Garrod, A.B.:, Gout and Rheumatic Gout. London: Walton and Maberly 1859.
Gehring, D., Jaedicke-Hollender, K.: Einfluß der Lithiumbehandlung auf die menschliche Schilddrüse und ihre Funktion. Münch, med. Wschr. 116, 1345 (1974).
Geisler, A., Wraae, Olesen, O.V.: Adenyl cyclase activity in kidneys of rats with lithium induced polyuria. Acta Pharmacol. (Kbh.) 31, 203 (1972).
Gerdes, H., Littmann, K.P., Joseph, IC., Mahlstedt, J.: Die Behandlung der Thyreotoxikose mit Lithium. Dtsch. med. Wschr. 98, 1551 (1973).
Gerdes, H., Littmann, K.P., Scheuer, A., Spuck, W., Köhler, F.: Experimentelle Studien über die Wirkung von Lithium auf die TSH-stimulierte Schilddrüse und die artefizielle Thyroxinintoxikation. Im Druck 1978.
Gerdes, H.: Symptomatologie und Therapie der Lithiumintoxikation. Verh. dtsch. Ges. inn. Med. 1976.
Gerdes, H., Schollmeier, B., Scheuer, A., Spuck, W.: Experimental studies about the effect of lithium on ACTH-stimulated adrenals. Acta endocr. (Kbh.) Suppl. 1977.
Gerdes, H., Spuck, W.: Bisher unveröffentlicht.
Gershengorn, M.C.: Use of lithium as an adjunct to radioiodine therapy of thyroid carcinoma. J. clin. Endocr. 42, 105 (1976).
Gershon, S., Yuwiler, A.: Lithiumion: A specific psychopharmacological approach to the treatment of mania. J. Neuropsychiat 1, 229 (1960).
Gibbons, J.L.: Cortisol secretion rate in depressive illness. Arch. gen. Psychiat. 10, 572 (1964).
Gordon, R., Küchel, O., Liddle, W., Island, D.: Role of the sympathetic nervous system in regulating renin and aldosterone production in man. J. clin. Invest. 46, 599 (1967).
Green, R.: Morning and afternoon plasma 17-hydroxycorticosteroid levels during affective psychosis. Int. J. Neuropsychiat. 3, 133 (1967).
Greenspan, K.: Tissue distribution patterns of lithium in the affective disorders. In: Lithium Research and Therapy (Ed. F.N. Johnson). New York-London: Academic Press 1975.
Greenspan, K., Aranoff, M.S., Bogdanski, D.F.: Effect of lithium carbonate on turnover and metabolism of norepinephrine in rat brain in correlation to gross behavioral effects. Pharmacology 3, 129 (1970).
Greenspan, K., Schildkraut, J J., Gordon, E.K., Baer, L., Aronoff, M.S., Durell, J.: Catecholamine metabolism in affective disorders. MHPG and other catecholamine metabolites in patients treated with lithium carbonate. J. psychiat. Res. 7, 171 (1970).
Gonzales, R., Lauter, H.: Zur Therapie manisch-depressiver Psychosen mit Lithium. Nervenarzt 39, 11 (1968).
Gotfredsen, C.F., Rafaelsen: Effect of lithium and other psychopharmaca on rat electrolyt metabolism. Int. Pharmacopsychiat. 5, 242 (1970).
Gutman, Y., Benzakein, F., Livneh, P.: Polydipsia induced by isoprenaline and by lithium: relation to kidneys and renin. Europ. J. Pharmacol. 16, 380 (1971).
Gutman, Y., Benzakein, F.: Effect of an increase and lack of antidiuretic hormone on plasma renin activity. Life Sci. 10, 1081 (1971).
Gutman, Y., Hochman, S., Wald, H.: The differential effect of lithium on microsomal ATPase in cortex, medulla and papilla of the rat kidney. Biochim. biophys. Acta (Amst.) 298, 284 (1973).
Gutman, Y., Tamir, N., Benzakein, F.: Effect of lithium on plasma renin activity. Europ. J. Pharmacol. 24, 347 (1973).
Halberg, P., Dige-Petersen, H., Werdelin, O., Simornson, J., Rafaelsen, O.J.: Thyroid gland function influenced by lithium treatment. Ugeskr. Laeg 130, 1521 (1968).
Hall, R.: Lithium in thyrotoxicosis. Lancet 1974II, 1521.
Halmi, K.A., Noyes, R.: Effect of lithium on thyroid function. Biol. Psychiat. 5, 211 (1972).
Halmi, K.A., Noyes, R., Millard, S.A.: Effect of lithium on plasma Cortisol and adrenal response to adrenocorticotropin in man. Clin. Pharmacol. Ther. 13, 699 (1972).
Harris, C.A., Jenner, F.A.: Some aspect of the inhibition of the action of antidiuretic hormone by lithium ions in the rat kidney and bladder of the toad Bufo marinus. Brit. J. Pharmacol. 44, 223(1972).
Harris, C.A., Dirks, J.H.: Effect of acute lithium infusion on proximal and distal tubular reabsorption in rats. Fed. Proc. 32, 381 (1973).
Haskovec, L., Rysanek, K.: Die Wirkung von Lithium auf den Metabolismus der Katecholamine und Indolalkylamine beim Menschen. Arzneimittel-Forsch. 19, 426 (1969).
Hellerström, G.: Effect of steroid diabetes on the pancreatic islets of guinea-pigs with special reference to the Ai-cells. Acta Soc. Med. upsalien. 68, 1 (1963).
Heltne, C.E., Ollerich, D.A.: Morphometric electron microscopic studies of a goiter induced by lithium in the rat. Amer. J. Anat. 136, 297–304 (1973).
Hendler, N., Uematsu, S., Long, D.M., Alwin, G.: Problems with lithium as treatment for inappropriate ADH-secretion. N. Engl. J. Med. 294, 446 (1976).
Heninger, G.R., Mueller, P.S.: Carbohydrat metabolism in mania. Before and after lithium carbonate treatment. Arch. gen. Psychiat. 23, 310 (1970).
Henneman, D., Zimmerberg, J.: Lack of effect chronic lithium chloride on bone. Endocrinology 94, 915 (1974).
Herrera, F.C., Egea, R., Herrera, A.M.: Movement of lithium across toad urinary bladder. Amer. J. Physiol. 220, 1501 (1971).
Herting, T., Lücke, Ch., Erbler, H.C.: Der Einfluß von Lithium auf die Plasmaspiegel von Vasopressin, Corticosteron, Aldosteron und Renin-Aktivität der Ratte. Acta endocr. (Kbh.) Suppl. (1977).
Ho, A.K.S., Loh, H.H., Craves, F., Hitzemann, R.J., Gershon, S.: The effect of prolonged lithium treatment on the synthesis rate and turnover of monoamines in brain regions of rats. Europ. J. Pharmacol. 10, 72 (1970).
Hochman, S., Gutman, Y.: Lithium: ADH antagonismus and ADH independent action in rats with diabetes insipidus. Europ. J. Pharmacol. 28, 100 (1974).
Hollister, L.E.: Complications from psychotherapeutic drugs. II. Rauwolfia alkaloids. New Engl. J. Med. 264, 345 (1961).
Holzbauer, M., Vogt, M.: Depression by reserpine of the noradrenaline concentration in the hypothalamus of the cat. J. Neurochem. 1, 8 (1956).
Horgan, J.H.: Antiarrhythmic effect of lithium. Arch. int. Pharmacodyn. 206, 105 (1973).
Horgan, J.H.: The effect of prophylactic and therapeutic administration of lithium on ventricular tachyarrhythmia. Arch. int. Pharmacodyn. 207, 77 (1974).
Horn, R.S., Walaas, O., Walaas, E.: The influence of sodium potassium and lithium. Biochim. biophys. Acta (Amst.) 313, 296 (1973).
Hullin, R.P., Johnson, A.W.: Effect of lithium salts on uptake of 125 I by fat thyroid gland. Life Sci. 9, 9 (1970).
Hullin, R.P., McDonald, R., Allsopp, M.: Prophylactic lithium in recurrent affective disorders. Lancet 1972 I, 1044.
Jenner, F.A.: The increased antidiuretic activity of rat urine following lithium administration. J. Physiol (Lond.) 245, 98 (1975a).
Jenner, F.: The effect of lithium ions on the antidiuretic action of vasopressin in the rat. Brit. J. Pharmacol. 55, 527 (1975b).
Jenner, F.A.: The effect of lithium ions on the antidiuretic action of vasopressin in the rat. Brit. J. Pharmacol. 55, 527 (1975c).
Jensen, S.E., Amdisen, A., Olsen, T., Schou, M.: Iodine metabolism in lithium therapy. Ugeskr. Laeg. 130, 1518 (1968).
Johnson, F.N.: Lithium research and therapy. London-New York: Academic Press 1975.
Jorgensen, J.V., Brandrup, F., Schroll, M.: Possible synergismus between iodine and lithium carbonate. J. Amer. med. Ass. 223, 192 (1973).
Karlsson, K.: Transplacental lithium poissoning. Reversible inhibition of fetal thyroid. Lancet 1975 I, 1295.
Katz, R.I., Chase, T.N., Kopin, I.J.: Evoked release of norepinephrine andSerotonine from brain slices by lithium. Science 162, 466 (1968).
Kendall-Taylor, P.: Comparison of the effect of various agent on thyroidal adenyl cyclase activity with their effect on thyroid hormone release. J. Endocr. 54, 137–142 (1972).
Kerry, R.J.: Liebling, L.J., Owen, G.: Weight changes in lithium responders. Acta psychiat. scand. 46, 238 (1970).
Kirkegaard-Hansen, A.: The effect of lithium on blood pressure and on plasma renin substrate and renin in rats. Acta Pharmacol. (Kbh.) 35, 370 (1974).
Kirkegaard, C., Lauridsen, U.B., Nerup, J.: Lithium and the thyroid. Lancet 1973 II, 1210.
Kristensen, O., Harrestrup-Andersen, H., Pallisgaard, G.: Lithium carbonate in the treatment of thyrotoxicosis. A controlled trial. Lancet 1976 I, 603.
Krulik, R., Zvolsky, P.: The influence of lithium ion on the adrenocortical function of rats. Arzneimittel-Forsch. 20, 1577 (1970).
Krulik, R., Zvolsky, P.: The effect of lithium on the metabolism of experimental animals. Activ. nerv. sup. (Praha) 12, 279 (1970).
Krulik, R., Janko, L., Cerny, M.: Metabolism of lipids in lithium administered rats. Acta Univ. Carol. Med. (Praha) 17, 533 (1971).
Krulik, R.: Effect of lithium on aldosterone production by rat adrenals. Arzneimittel-Forsch. 21, 889(1971).
Kuriyama, K., Speken, R.: Effect of lithium on content and uptake of norepinephrine and 5-hydroxy-tryptamine in mouse brain synaptomes and mitochondria. Life Sci. 9, 1213 (1970).
Lauridsen, U.B., Kirkegaard, C., Nerup, J.: Lithium and the pituitary-thyroid axis in normal subjects. J. clin. Endocr. 39, 383–385 (1974).
Lauter, H.: Schilddrüsenstörung durch Lithiumtherapie. Dtsch. med. Wschr. 96, 805 (1971).
Lazarus, J.H., Bennie, E.H.: Effect of lithium on thyroid function in man. Acta endocr. (Kbh.) 70, 266(1972).
Lazarus, J.H., Richards, A.R., Addison, G.M., Owen, G.M.: Treatment of Thyrotoxicosis by lithium carbonate. Lancet 1974 II, 1160–1162.
Lee, R.V., Jampol, L.M., Brown, M.V.: Nephrogenic diabetes insipidus and lithium intoxication. — Complications of lithium carbonate therapy. New Engl. J. Med. 284, 93(1971).
Leonetti, G., Mayer, G., Morganti, A., Terzoli, L., Zanchetti, A. et al.: Hypotensive and renin suppressing activities of propranolol in hypertensive patients. Clin. Sci. 48, 491 (1975).
Leonhardt, K.F.: Pharmakodynamische Aspekte der Lithiumtherapie. Dtsch. med. Wschr. 99, 715 (1974).
Lernmark, A., Hellman, B., Corre, H.G.: Effect of gastrin on the release of insulin in vitro. J. Endocr. 43, 371 (1969).
Lernmark, A., Hellman, B.: The beta-cell capacity for insulin secretion in microdissected pancreatic islets from obese-hyperglycemic mice. Life Sci. 8, 53 (1969).
Levy, St., T., Forrest, J.N., Hetlinger, G.R.: Chlorothiocid therapy of lithium induced diabetes insipidus. Amer. J. Psychiat. 130, 1014 (1973).
Lindop, G.B.: The renal pathology in a case of lithium-induced diabetes insipidus. J. clin. Path. 28, 472(1975).
Ljungren, J.C., Sedvall, G., Levin, K., Fyrö, B.: Influence of lithium ion on the biosynthesis of thyroxine and thyreoglobulin in the rat. Acta endocr. (Kbh.) 67, 784 (1971).
Lloyd, G.G., Rosser, R.M., Crowe, M.J.: Effect of lithium on thyroid in man. Lancet 1973 11, 619.
Luby, E.D., Schwartz, D., Rosenbaum, H.: Lithium-carbonate-induced Myxedema. J. Amer. med. Ass. 218, 1298(1971).
Lunde, D.T., Hamburg, D.A.: Techniques for assessing the affects of sex hormones on affect, arousal and agression in human. Recent Progr. Hormone Res. 28, 627 (1972).
Lindstedt, G., Lundberg, P.A., Tofft, M., Akesson, H.O., Öhman, R.: Serum thyrotropin and hypothyroidism during lithium therapy. Clin. chim. Acta 48, 127 (1973).
MacLeod, J., Swan, R.C., Aitken, G.A.: Lithium its effect on human spermatozo, rat testicular tissue and upon rats in vivo. Amer. J. Physiol. 157, 177 (1949).
Malaisse, W.J., Malaisse-Lagae, F.: A possible role for calcium in the stimulus-secretion coupling for glucose-induced insulin secretion. Acta diabet. lat. 7 (Suppl. 1) 264 (1970).
Malaisse, W.J., Malaisse-Lagae, F., Brisson, G.: The stimulus-secretion coupling of glucose-induced insulin release. II. Interaction of alkali and alkali-earth cations. Hormone Metab. Res. 3, 65 (1971).
Mandell, AJ.: Effect of lithium on serotonin. Neurosci. Res. Programm Bull. 14, 169 (1976).
Männistö, P., Linnoila, M., Leppäluoto, J.: Studies with lithium in euthyrotic, hyperthyrotic and hypothyrotic rats. Life Sci. 10, 9 (1971).
Männistö, P., Koivisto, V.: Antidiabetic effect of lithium. Lancet 1972 II, 1031.
Männistö, P.T., Leppäluoto, J., Virkkunen: Complex antithyroid properties of the lithium ion. Acta endocr. (Kbh.) 74, 492 (1973).
Männistö, P.T.: Thyroid iodine metabolism in vitro. II. Effect of lithiumion. Ann. Med. exp. Fenn. 51, 42 (1973).
Männistö, P.T.: Inhibitory effect of lithium on uptake and incorporation of thyrosine into protein in three thyroid preparations in vitro. Med. Biol. 52, 250 (1974).
Marcus, R., Aurbach, G.D.: Adenyl cyclase from renal cortex. Biochim. biophys. Acta (Amst.) 242, 410(1971).
Martinez-Sierra, R.: Influence of lithium chloride on adrenergic mechanisms in ventricle of frog heart and guinea pig left atrium. Experientia (Basel) 31, 101 (1975).
Masek, O.: Use of lithium salts in the treatment of hyperthyroidism. Vnitrni Lek. 20, 1033(1974).
McLarthy, D.G., O’Boyle, J.H., Spencer, C.A., Ratcliffe, J.G.: Effect of lithium on hypo-thalamic-pituitary-thyroid function in patients with affective disorders. Brit. med. J. 1975 III, 623.
Mellerup, E.T., Plenge, P., Ziegler, R., Rafaelsen, O.J.: Lithium effects on calcium metabolism in rats. Int. Pharmacopsychiat. 5, 264 (1970).
Mellerup, E.T., Gronlund, H., Plenge, P., Rafaelsen, O.J.: Lithium effect on plasma glucagon, liver phosphorylase-a and liver glycogen in rats. J. psychiat. Res. 8, 37 (1970).
Mellerup, E.T., Thomsen, H., Gronlund, N., Rafaelsen, O.J.: Lithium weight gain, and serum insuline in manic depressive patients. Acta psychiat. scand. 48, 332 (1972).
Mellerup, E.T., Rafaelsen, O.J.: Lithium and carbohydrate metabolism. In: Lithium Research and Therapy (Ed. F.N. Johnson), p. 384. New York-London: Academic Press 1975.
Mendelsohn, M.: Diuretische Wirkung von Lithiumsalzen. Dtsch. med. Wschr. 2, 673 (1895).
Murphy, D.L., Colburn, R.W., Davis, J.M., Bunney, W.E.: Stimulation by lithium monoamine uptake in human platelets. Life Sci. 8, 1187 (1969).
Murphy, D.L., Goodwin, F.K., Bunney, W.E.: Aldosterone and sodium response to lithium administration in man. Lancet 1969 II, 458.
Ohlin, G., Söderberg, U.: Inhibition of peripheral utilization of thyroid hormones induced by lithium. Acta physioL scand. 79, 24 A (1970).
Olesen, O.V., Thomsen, K.: Effect of prolonged lithium ingestion on glucagon and parathyroid hormone responses in rats. Acta Pharmacol. (Kbh.) 34, 225 (1974a).
Olesen, O.V., Jensen, J., Thomsen, K.: Effect of lithium on glucagon-stimulated cAMP-excretion in rats. Acta Pharmacol. (Kbh.) 35, 403 (1974b).
Paloma de la Losa, M., Justiz, M.: A propos de la liberation de Fhormon folliculo-stimulante (FSH) in vitro a partir de l’hypophyse de rat sons l’effect des ions potassium. C.R. Soc. BioL (Paris) 165, 1815 (1971).
Petersson, B., Hellerström, G., Gunnarson, R.: Structure and metabolism of the pancreatic islets in streptozotocin treated guinea-pigs. Hormone Metab. Res. 2, 313 (1970).
Petersson, B., Shopsin, B.: Effect of lithium chlor id on the islets of Langerhans in guinea pigs. Acta endocr. (Kbh.) 70, 731 (1972).
Platman, S.R., Fieve, R.R.: Lithium carbonate and plasma Cortisol response in affective disorders. Arch. gen. Psychiat. 18, 591 (1968).
Platman, S.R., Hilton, J.G., Koss, M.C.: Production of Cortisol in patients with manicdepressive psychosis treated with lithium carbonate. Dis. nerv. Syst. 32, 542 (1971).
Plenge, P., Mellerup, E.T., Rafaelsen, O J.: Lithium action on glycogen synthesis in rat brain, üver and diaphragma. J. psychiat. Res. 8, 29 (1970).
Plenge, P., Mellerup, E.T., Rafaelsen, O J.: Lithium action on rat phosphat metabolism. Int. Pharmacopsychiat. 6, 52 (1971).
Pousset, G., Briere, J., Berthezene, F., Tourniaire, J., Devie, M.: Myxedema due to lithium. Clinical and physiopathological study apropos 2 cases. Ann. Endoer. (Paris) 34, 454 (1973).
Pürgyi, P.: Über den Zusammenhang zwischen Glucosetoleranz und Depression sowie deren Therapie mit MAO-Hemmern und Lithiumsalzen. Nervenarzt 43, 379 (1972).
Radvila, A., Roost, R., Bürgi, H., Kohler, H., Studer, H.: Inhibition of thyroglobulin biosynthesis and degradation by excess iodide. Acta endocr. (Kbh.) 81, 495 (1976).
Ramsey, T.A., Mendels, J., Stokes, J.W., Fitzgerald, R.G.: Lithium carbonate and kidney function. J. Amer. med. Ass. 219, 1446 (1972).
Rifkin, A., Quitkin, F., Blumberg, A.G., Klein, D.F.: The effect of lithium on thyroid functioning: A controlled study. J. psychiat. Res. 10, 115 (1974).
Rizzo, N.D., Fox, H.M., Laidlow, J.C.: Concurrent observations of behavior changes and of adrenocortical variations in a cyclothymic patient during period of 12 months. Ann. intern. Med. 41, 798 (1954).
Rogers, M.P., Whybrow, P.C.: Clinical hypothyroidism occurring during lithium treatment: two cases and a review of thyroid function in 19 patients. Amer. J. Psychiat. 128, 158 (1971). R
Rosser, R.: Thyrotoxicosis and lithium. Brit. J. Psychiat. 128, 61 (1976).
Rybakowski, J., Sowinski, J.: Free Thyroxine index and absolute free thyroxin in affective disorders. Lancet 1973 I, 889.
Saberi, M., Utiger, R.: Lack of effect of lithium on serum thyroxine and triiodothyronine levels and thyrotropin secretion in thyroxine-treated hypothyroid patients. Hormone Metab. Res. 7, 361 (1975).
Sachar, E.J., Hellman, L., Kream, J., Fukushima, D.K., Gallagher, T.E., Broux, N.Y.: Effect of lithiumcarbonate therapy on adrenocortical activity. Arch. gen. Psychiat. 22, 304 (1970).
Sachar, EJ., Hellman, L., Fukushima, DF.: Cortisol production in mania. Arch. gen. Psychiat. 26, 137 (1972).
Sachar, E.J., Hellman, L., Fukushima, D.K.: Cortisol production in depressive illness. Arch. gen. Psychiat. 23, 289 (1970).
Samols, E., Marri, G., Marks, V.: Promotion of insulin secretion by glukagon. Lancet 1965 1, 415.
Sanchez, R.S., Murthy, G.G., Mehta, J., Shreeve, W.W., Singh, F.R.: Pituitary-testicular axis in patients on lithium therapy. FertiL and Steril. 27, 667 (1976).
Sedvall, G.B., Jönsson, B., Pettersson, U., Levin, K.: Effect of lithium salts on plasma bound iodine and uptake of J131 thyroid gland of man and rat. Life Sci. 7, 1257 (1968).
Sedvall, G.C., Jönsson, B., Pettersson, U.: Evidence of an altered thyroid function in man during treatment with lithium carbonate. Acta psychiatr. scand. Suppl. 207, 59 (1969).
Segaard, E.: Lithium induced hypothyroidism. T. norske Laegeforen. 95, 434 (1975).
Segal, R.L., Rosenblatt, S., Eliasopf: Endocrine exophthalmos during lithium therapy of manic depressive disease. New Engl. J. Med. 289, 136 (1973).
Segal, D.S., Callaghan, M., Mandell, A.J.: Alterations in behaviour and catecholamin-biosynthesis induced by lithium. Nature 254, 58 (1975).
Shaw, D.M.: Lithium and amine metabolism. In: Lithium Research and Therapy (Ed. F.N. Johnson). New York-London: Academic Press 1975.
Shopsin, B., Blum, M., Gershon, S.: Lithium-induced thyroid disturbance case report and review. Comprehens. Psychiat. 10, 215 (1969).
Shopsin, B : Effects of lithium on thyroid function. Dis. nerv. Syst. 31, 237 (1970).
Shopsin, B., Stern, S., Gershon, S.: Altered carbohydrate metabolism during treatment with lithium carbonate. Arch. gen. Psychiat. 26, 566 (1972).
Shopsin, B., Shenkman, L., Blum, M., Hollander, C.S.: Iodine and lithium-induced hypothyroidism. Amer. J. Med. 55, 695 (1973).
Shopsin, B., Sathananthan, G., Gershon, S.: Plasma renin response to lithium in psychiatric patients. Clin. Pharmacol. Ther. 14, 561 (1973).
Simpson, G.M.: Lithium and thyroid function. Amer. J. Psychiat. 125, 1132 (1969).
Singer, I., Rotenberg, D., Puschett, J.B.: Lithium induced nephrogenic diabetes insipidus: in vivo and in vitro studies. J. clin. Invest. 51, 1081 (1972).
Singer, J.N., Franko, E.A.: Lithium-induced ADH resistance in toad urinary bladders. Kidney Int. 3, 151 (1973).
Singer, J., Rotenberg, D.: Mechanisms of Lithium action. New Engl. J. Med. 289, 254 (1970).
Smith, D.F., Balagura, S., Lubran, M.: “Antidotal thirst”: a response to intoxication. Science 167, 297(1970).
Smith, D.F., Balagura, S.: Sodium appetite in rats given lithium. Life Sci. 11, 1021 (1972).
Sober, A.J., Görden, P.: Pituitary responsioness to aqueous vasopressin in patients with congenital vasopressin-resistent diabetes insipidus. J. clin. Endoer. 35, 924 (1972).
Spaulding, S.W., Burrow, G.N., Bermudez, F., Himmelhoch, J.M.: The inhibitory effect on thyroid hormone release in both euthyroid and thyrotoxic patients. J. clin. Endoer. 35, 905 (1972).
Stern, D.M., Fieve, R., Neff, N., Costa, E.: Effect of lithium on turnover of brain and heart catecholamines. Pharmacologist 9, 210 (1967).
Schanberg, S.M., Schildkraut, J.J., Kopin, I.J.: Effect of psychoactive drugs on norepinepi-nephrine-3H metabolism in brain. Biochem. Pharmacol. 16, 393 (1967).
Schanberg, S.M., Schildkraut, J.J., Breese, G.R., Kopin, I.J.: Metabolism of normetanephrine-3 H in rat brain: Identification of conjugated 3-methoxy-4-hydroxyphenylglycol as major metabolite. Biochem. Pharmacol. 17, 247 (1968).
Schildkraut, J.J.: The catecholamine hypothesis of affective disorders: A review of the supporting evidence. Amer. J. Psychiat. 122, 509 (1965).
Schildkraut, J.J., Schanberg, S.M., Kopin, I.J.: Effect of lithium ion on 3 H-norepinephrine metabolism in brain. Life Sci. 5, 1479 (1966).
Schildkraut, J.J., Lague, M.A., Dodge, G.A.: Effects of lithium salts on turnover an metabolism of norepinephrine in rat brain. Psychopharmacologia 14, 135 (1969).
Schildkraut, J.J.: In: Lithium: Its role in psychiatric research and treatment (Eds. Gershon, S., Shopsin, B.), pp. 51–73. New York-London: Academic Press 1973.
Schildkraut, J.J.: The effect of lithium on norepinephrine turnover and metabolism: basic and clinical studies. J. Nerv. ment. Dis. 158, 348 (1974).
Schofield, J.G.: Effect of sulphydryl reagents on the release of growth hormone in vitro. Biochim. biophys. Acta (Amst.) 252, 516 (1971).
Schou, M.: Biology and pharmacology of the lithium ion. Pharmacol. Rev. 9, 17 (1957).
Schou, M., Amdisen, A., Trap-Jensen, J.: Lithium poisoning. Amer. J. Psychiat. 125, 520 (1968).
Schou, M., Amdisen, A., Jensen, S.E., Olsen, T.: Occurrence of goitre during lithium treatment. Brit. med. J. 1968 III, 710.
Schou, M.: Pharmacology and toxicology of lithium. Ann. Rev. Pharmacol. 16, 231 (1976).
Schreiber, V., Rohacova, J.: Diuretic action of lithium carbonate in rats. Acta endocr. (Kbh.) 68, 686 (1971).
Schreiber, F., Rohacova, J., Pribyl, T.: Endocrine changes after chronic lithium carbonate administration in rats. Physiol, bohemoslov. 20, 249 (1971).
Schwartz, W.B., Bennet, W., Curelop, S.: A syndrome of renal sodium loss and hyponatriemia probably resulting from inappropriate secretion of antidiuretic hormone. Amer. J. Med. 23, 529 (1957).
Schwartz, W.B., Tassel, D., Bartter, F.C.: Further observations on hyponatriemia and renal sodium loss probably resulting from inappropriate secretion of antidiuretic hormone. N. Engl. J. Med. 262, 743 (1960).
Steele, T.H., Dudgeon, K.L.: Reabsorption of lithium and phosphate by the rat kidney: role of parathyroids. Kidney Int. 5, 196 (1974).
Steele, T.H.: Selective lithium inhibition of hormonal phosphaturie responses. J. Pharmacol, exp. Ther. 197, 206(1976).
Takahashi, S.: Thyroid function levels and thyrotropin responses to TRH administration in manic patients receiving lithium carbonate. Folia psychiat. neurol. jap. 29, 231 (1975).
Temple, R., Berman, M., Carlson, H.E., Robbins, J., Wolff, J.: The use of lithium in Graves’ disease. Proc. Mayo Clin. 47, 872 (1972a).
Temple, R., Berman, M., Robbins, J., Wolff, J.: The use of lithium in the treatment of thyrotoxicosis. J. clin. Invest. 51, 2746 (1972b).
Thomsen, K., Schou, M.: Renal lithium excretion in man. Amer. J. Physiol. 215, 823 (1968).
Thomsen, K., Schou, M., Steiness, I., Hansen, H.E.: Lithium as an indicator of proximal sodium reabsorption. Pflügers Arch. ges. Physiol. 308, 180 (1969).
Torp-Pederson, C., Thorn, N.A.: Acute affects of lithium on the action and release of ADH in rats. Acta endocr. (Kbh.) 73, 665 (1973).
Trautner, E.M., Morris, R., Noack, C.H.: The excretion and retention of ingested lithium and its effect on the ionic balance of man. Med. J. Aust. 2, 280 (1955).
Tupin, J.P., Schlangenhauf, G.K., Creson, D.L.: Lithium effects on electrolyt excretion. Amer. J. Psychiat. 125, 536 (1968).
Turner, J.G., Brownlie, B.E.W., Sadler, W.A., Jensen, C.H.: An evaluation of lithium as an adjunct to Carbimazole treatment in acute thyrotoxicosis. Acta endocr. (Kbh.) 83, 86 (1976).
Turner, J.G., Brownlie, B.E., Rogers, T.G.J.: Lithium as an adjunct to radioiodine therapy for thyrotoxicosis. Lancet 1976 I, 614.
Van der Velde, C.D., Gordon, H.W.: Manic-depressiv illness, diabetes mellitus and lithium carbonate. Arch. gen. Psychiat. 21, 478 (1969).
Vendsberg, P.B., Pryth, S.: Glucose tolerance and serum lipids in man after long-term lithium administration. Acta psychiat. scand. 53, 64 (1976).
Vendsborg, P.B., Vilstrup, H.: The influence of lithium on carbohydrate and lipid metabolism in the perfused rat liver. Acta Pharmacol. (Kbh.) 38, 10 (1976).
Vendsborg, P.B., Rafaelsen, O.J.: Lithium in man: Effect on glucose tolerance and serum electrolytes. Acta psychiat. scand. 49, 601 (1973).
Vendsborg, P.B., Mellerup, E.T., Rafaelsen, O.J.: Lithium in man. Serum electrolytes and glucose after a single lithium load. Acta psychiat. scand. 49, 97 (1973).
Villeneuve, A., Gautier, J., Jus, A., Perron, D.: Effect of lithium on thyroid in man. Lancet 1973 II, 502.
Viol, G.W., Smith, E.K.: Vasopressin inhibition by lithium. New Engl. J. Med. 284, 674 (1971).
Vizi, E.S.: Lithium and acetylcholin metabolism. In: Lithium Research and Therapy (Ed. F.N. Johnson). New York-London: Academic Press 1975.
Waal, H.: Propranolol-induced depression. Brit. med. J. 1967 II, 50.
Walaas, O., Walaas, E., Wick, A.N.: The stimulatory effect by insulin on the incorporation of 32P radioactive inorganic phosphat into intracellular inorganic phosphate, adenine nucleotides and guanine nucleotides of the intact isolated rat diaphragm. Diabetologia 5, 79(1969).
Wartofsky, L., Ransil, B.J., Ingbar, S.H.: Inhibition by iodine of the release of thyroxine from the thyroid glands of patients with thyrotoxicosis. J. clin. Invest. 49, 78 (1970).
Weiss, H.: Über eine neue Behandlungsmethode des Diabetes mellitus und verwandter Stoffwechselstörungen. Wien. klin. Wschr. 37, 1142 (1924).
White, M.G., Fettner, C.D.: Treatment of the syndrome of inappropriate secretion of antidiuretic hormone with lithium carbonate. N. Engl. J. Med. 292, 390 (1975).
Wiener, J.D.: Lithium carbonate-induced myxedema. J. Amer. med. Ass. 220, 587 (1972).
Wiggers, A.S.: Effects of lithium on the thyroid gland. Ugeskr. Laeg. 130, 1523 (1968).
Williams, J.A., Berens, S.C., Wolff, J.: Thyroid secretion in vitro: Inhibition of TSH and dibutyryl cyclic-AMP stimulated 131 I-release by lithium. Endocrinology 88, 1385 (1971).
Willis, J.S., Fang, L.S.T.: Lithium stimulation of ouabain-sensitive respiration and (Na+-K+)-ATTase of kidney cortex of ground squirrels. Biochim. biophys. Acta (Amst.) 219, 486(1970).
Winer, N., Chokshi, D.S., Walkenhoarst, W.G.: Effect of CAMP, sympathomimetic amines and adrenergic receptor antagonists on renin secretion. Circulât. Res. 29, 239 (1971).
Wittrig, J., Woods, A.E., Anthony, E.J.: Mechanisms of lithium action. Dis. nerv. Syst. 31, 767(1970).
Wolff, J., Berens, S.C., Jones, A.B.: Inhibition of thyreotropin-stimulated adenyl cyclase activity of beef thyroid membrane by low concentrations of lithium. Biochem. biophys. Res. Commun. 39, 77 (1970).
Wraae, O., Geisler, A., Olesen, O.V.: The relation between vasopressin stimulation of renal cyclase and lithium-induced polyuria in rats. Acta Pharmacol. (Kbh.) 31, 314 (1972).
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 1978 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Gerdes, H. (1978). Lithium und Endokrinium. In: Frick, P., von Harnack, GA., Martini, G.A., Prader, A., Schoen, R., Wolff, H.P. (eds) Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics. Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics, vol 40. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66830-2_2
Download citation
DOI: https://doi.org/10.1007/978-3-642-66830-2_2
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-66831-9
Online ISBN: 978-3-642-66830-2
eBook Packages: Springer Book Archive