The Renin-Angiotensin System

1. Front Matter

   Pages I-XII

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2. Introduction

   • Hideshi Kobayashi, Yoshio Takei

   Pages 1-9

3. Comparative Morphology of the Juxtaglomerular Apparatus (JGA)

   • Hideshi Kobayashi, Yoshio Takei

   Pages 11-35

4. Innervation in the JGA

   • Hideshi Kobayashi, Yoshio Takei

   Pages 37-40

5. Tissue Distribution of the RAS

   • Hideshi Kobayashi, Yoshio Takei

   Pages 41-51

6. Regulation of Renin Release

   • Hideshi Kobayashi, Yoshio Takei

   Pages 53-75

7. Biochemistry of the RAS

   • Hideshi Kobayashi, Yoshio Takei

   Pages 77-89

8. Angiotensin Receptors

   • Hideshi Kobayashi, Yoshio Takei

   Pages 91-111

9. Biological Actions of ANG II

   • Hideshi Kobayashi, Yoshio Takei

   Pages 113-172

10. General Conclusions

    • Hideshi Kobayashi, Yoshio Takei

    Pages 173-178

11. Back Matter

    Pages 179-245

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The renin-angiotensin system and the mechanisms regulating this system developed during the adaptive evolution of verte­ brates, along with many other systems involved in the in­ tegrated survival of the organism. Because animal species have evolved from common ancestral populations, a basis for the comparison of body structures and physiological processes ex­ ists among animal groups belonging to different classifications. The comparative approach provides a better understanding of the structure and function of adaptive systems and facilitates the development of general principles governing these systems among animal groups; further, this approach reveals significant characteristics specific to certain animal groups. As the evolu­ tion of adaptation of animals to environmental conditions is explored, directions for future research are suggested. In this book, advances in research on the renin-angiotensin system are described with emphasis on the comparative aspects. However, since studies on the renin-angiotensin system of birds, reptiles, amphibians and fishes are limited compared with those con­ ducted in mammals, in some chapters descriptions are con­ cerned primarily with mammals. It has taken a long time to write this volume, and the topic is a broad one, with new data always emerging; therefore, certain aspects, and sometimes the most recent information, may not be included. Chapters 1-3 and sections 8. 1-8. 4,8. 6, 8. 7 were written by H. K. ; Chapters 4-7 and Section 8. 5 by Y. T. ; Chapter 9 was written by both authors. H. Uemura, M. Nozaki, Y. Okawara, We are indebted to Drs.

• Angiotensin II receptor
• Angiotensin-II-Rezeptor
• Blood pressure
• Body fluids
• Durst
• Hormone
• Hormones
• Juxtaglomerular apparatus
• Juxtaglomerular-Apparat
• Körperflüssigkeiten
• Natriumappetit
• Renin-Angiotensin-System
• Renin-angiotensin system
• Sodium ap

• University of Tokyo, Zenyaku Kogyo Co., Ltd., Nerima-ku, Japan

  Hideshi Kobayashi

• Ocean Research Institute, University of Tokyo, Nakano-ku, Japan

  Yoshio Takei

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