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Natural History of Prostate Cancer

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Carcinoma of the Prostate

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Knowledge of the natural history of prostate cancer is needed to give an indication of the prognosis once the tumor is diagnosed. The patient requires information about the expected course of the disease before a decision can be made about treatment. Several treatment options are available in the case of localized disease. Radical prostatectomy and radiotherapy are advocated for local treatment with curative intention. There is extensive debate over whether treatment is necessary in prostate cancer patients in whom it is possible, and on the other hand whether treatment is possible in those in whom it is needed (Whitmore 1988).

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References

  • Adolfsson J, Carstensen J (1991) Natural course of clinical localised prostate adenocarcinoma in men less than 70 years old. J Urol 146:96–98

    PubMed  CAS  Google Scholar 

  • Adolfsson J, Ronstrom SO, Carstensen J (1990) The natural course of low grade, non metastatic prostatic carcinoma. Br J Urol 65:611–614

    Article  PubMed  CAS  Google Scholar 

  • Adolfsson J, Carstensen J, Löwhagen T (1992) Deferred treatment in clinically localized prostatic carcinoma. Br J Urol 69:183–187

    Article  PubMed  CAS  Google Scholar 

  • Aus G, Hugosson J, Norlén L (1995) Long term survival and mortality in prostate cancer treated with non curative intent. J Urol 154:460–465

    Article  PubMed  CAS  Google Scholar 

  • Blackard CE, Byar DP, Jordan WP (1971) Treatment of stage 1 carcinoma of the prostate: a preliminary report. J Urol 106:729–733

    PubMed  CAS  Google Scholar 

  • Blute ML, Zincke H, Farrow GM (1986) Long term follow up of young patients with stage A adenocarcinoma of the prostate. J Urol 136:840–843

    PubMed  CAS  Google Scholar 

  • Bosch R, Kurth KH, Schröder FH (1987) Surgical treatment of locally advanced (T3) prostatic carcinoma - early results. J Urol 138:816–822

    PubMed  CAS  Google Scholar 

  • Bostwick DG (1989) Prostatic intraepithelial neoplasia (PIN). Urology 34 (Suppl):16–22

    PubMed  CAS  Google Scholar 

  • Byar DP, Corle DK, Veterans Administration Cooperative Urological Research Group (1991) VACURG randomized trial of radical prostatectomy for stages I and II prostate cancer. Urology 17:7–11

    Google Scholar 

  • Cantrell BB, De Klerk DP, Eggleston JC (1981) Pathological factors that influence prognosis in stage A prostatic cancer: the influence of extent versus grade. J Urol 125:516–520

    PubMed  CAS  Google Scholar 

  • Chodak GW, Thisted RA, Gerber GJ et al. (1994) Results of conservative management of clinically localized prostate cancer. N Engl J Med 330:242–248

    Article  PubMed  CAS  Google Scholar 

  • Correa RJ Jr, Anderson RG, Gibbons RP, Mason J (1974) Latent carcinoma of the prostate-why the controversy? J Urol 111:644–646

    PubMed  Google Scholar 

  • Cumming JA (1990) Dedifferentiation with time in prostate cancer and the influence on the course of the disease. Br J Urol 65:271–274

    Article  PubMed  CAS  Google Scholar 

  • Douglas TH, Sesterhen IA, Moul JDN, McLeod DG (1995) The significance of PSA detected, nonpalpable adenocarcinoma of the prostate (stage Tic). J Urol 153 (Suppl):251A

    Google Scholar 

  • Epstein JL, Paul LG, Eggleston JC, Walsh PC (1986) Prognosis of untreated stage 1 prostatic carcinoma: a study of 94 cases with extended follow up. J Urol 136:837–839

    PubMed  CAS  Google Scholar 

  • Epstein JL, Walsh PC, Marué C, Brendler CB (1994) Pathologic and clinical findings to predict tumor extent of nonpalpable (stage Tic) prostate cancer. JAMA 271:368–374

    Article  PubMed  CAS  Google Scholar 

  • Flanigan RC, Mohler JL, King CT, Atwell JR, Umer MA, Loh FK, McRoberts JW (1985) Preoperative lymph node evaluation in prostatic cancer patients who are surgical candidates: the role of lymphangiography and computerized tomography scanning with directed fine needle aspiration. J Urol 134:84

    PubMed  CAS  Google Scholar 

  • Franks LM (1954) Latent carcinoma of the prostate. J Pathol Bacteriol 68:603–616

    Article  PubMed  CAS  Google Scholar 

  • Franks LM (1973) Etiology, epidemiology and pathology of prostatic cancer. Cancer 32:1092–1095

    Article  PubMed  CAS  Google Scholar 

  • George NJR (1988) Natural history of localised prostatic cancer managed by conservative treatment alone. Lancet I:494–497

    Article  Google Scholar 

  • Grossman IC, Carpiniello V, Greenberg SH, Malloy TR, Wein AJ (1980) Staging pelvic lymphadenectomy for carcinoma of the prostate: review of 91 cases. J Urol 124: 632

    PubMed  CAS  Google Scholar 

  • Hackler RH, Texter JH Jr (1980) Evaluation and management of early stages of carcinoma of prostate. Urology 15:329

    Article  PubMed  CAS  Google Scholar 

  • Handley R, Carr TW, Travis D, Powell PM, Hall RR (1988) Deferred treatment of prostate cancer. Br J Urol 62:249–253

    Article  PubMed  CAS  Google Scholar 

  • Jewett HJ (1975) The present status of radical prostatectomy for stage A and B prostate cancer. Urol Clin North Am 2:105–124

    PubMed  CAS  Google Scholar 

  • Johansson JE, Adami MO, Andersson SO, Bergstrom R, Krusemo M, Kraaz W (1989) Natural history of localised prostatic cancer. Lancet I:799–803

    Article  Google Scholar 

  • Johansson JE, Adami MO, Andersson SO, Bergstrom R, Holmberg L, Krusemo M (1992) High 10 year survival rate in patients with early, untreated prostatic cancer. JAMA 267:2191–2196

    Article  PubMed  CAS  Google Scholar 

  • Lowe BA, Liström MB (1988) Incidental carcinoma of the prostate: an analysis of the predictors of progression. J Urol 140:1330–1344

    Google Scholar 

  • Petros JA, Catalona WJ (1992) Lower incidence of unsuspected lymph node metastases in 521 consecutive patients with clinical localized prostate cancer. J Urol 147:1574–1575

    PubMed  CAS  Google Scholar 

  • Sakr WA, Haas GP, Cassin BF, Pontes JE, Crissman JD (1993) The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients. J Urol 150:379–389

    PubMed  CAS  Google Scholar 

  • Schellhammer PF (1994) Contemporary expectant therapy series: a viewpoint. Urology 44:47–52

    Article  Google Scholar 

  • Schröder FH, Blom JHM, Bosch JLHR (1989) Considerations on surgical management of locally advanced prostatic carcinoma In: Paulson DF (ed) Prostatic disorders. Lea and Febiger, Philadelphia, p 330

    Google Scholar 

  • Stilwell TJ, Malch RS, Enger DE, Farrow GM (1989) Incidental adenocarcinoma after open prostatic adenomectomy. J Urol 141:76–78

    Google Scholar 

  • Thompson IM, Zeidman EJ (1989) Extended follow up of stage Al carcinoma of the prostate. Urology 33:455–458

    Article  PubMed  CAS  Google Scholar 

  • van Aubel OGJM, Hoekstra WJ, Schröder FH (1985) Early orchiectomy for patients with stage D1 prostatic carcinoma. J Urol 134:292–294

    PubMed  Google Scholar 

  • Warner W, Whitmore WF Jr (1990) Expectant management of localized prostatic cancer. Abstract and oral communication, Canadian Urological Association, Vancouver

    Google Scholar 

  • Whitmore WF (1994) Localised prostatic cancer: management and detection issues. Lancet 343:1263–1267

    Article  PubMed  Google Scholar 

  • Whitmore WF (1988) Overview: historical and contemporary. NCI Monogr 7:7–11

    PubMed  Google Scholar 

  • Whitmore WF, Warner JA, Thompson IM (1991) Expectant management of localised prostatic cancer. Cancer 67:1191–1196

    Article  Google Scholar 

  • Zhang G, Wasserman NF, Ami Sidi A, Reinberg J, Reddy PK (1991) Long term follow up results after expectant management of stage Al prostatic cancer. J Urol 146:99–103

    PubMed  CAS  Google Scholar 

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© 1996 Springer-Verlag Berlin Heidelberg

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Kirkels, W.J. (1996). Natural History of Prostate Cancer. In: Petrovich, Z., Baert, L., Brady, L.W. (eds) Carcinoma of the Prostate. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60956-5_2

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  • DOI: https://doi.org/10.1007/978-3-642-60956-5_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64627-0

  • Online ISBN: 978-3-642-60956-5

  • eBook Packages: Springer Book Archive

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