Abstract
The platelet membrane glycoprotein (GP) Ib/lX complex plays a pivotal role in primary haemostasis, serving as a platelet receptor for von Willebrand factor. This complex contains three polypeptide chains: GPlb-α, GPlb-β and GPI-X. Glycocalicin is a soluble proteolytic fragment of GPlb-α and is normally present in the circulation. Previous work using an enzyme-linked immunosorbent assay has shown injury or platelet destruction in vivo [1]. The aim of this study was to develop a rapid assay for glycocalicin which could be used in the differential diagnosis of thrombocytopaenia
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References
Kunishima S, Hayashi K, Kobayashi S et al (1991) New enzyme-linked immunosorbent assay for glycocalcin in plasma. Clin Chern 37:169–172
Kunishima S, Kobayashi S, Takagi A et al (1993) Rapid detection of plasma glycocalcin by a latex agglutination test. Am J Clin Pathol l00:579–582
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© 1997 Springer-Verlag Berlin · Heidelberg
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Kunishima, S., Kobayashi, S., Saito, H., Naoe, T. (1997). Rapid Detection of Plasma Glycocalicin by a Latex Agglutination Test and Its Use in the Differential Diagnosis of Thrombocytopaenia. In: List, W.F., Müller, M.M., McQueen, M.J. (eds) Advances in Critical Care Testing. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60735-6_43
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DOI: https://doi.org/10.1007/978-3-642-60735-6_43
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-62590-2
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