Abstract
Acute liver failure (ALF) is a syndrome resulting from massive hepatocyte death leading to hepatic dysfunction. The main manifestations of ALF are jaundice with rapidly progressive encephalopathy, coagulopathy and eventually multi-organ dysfunction. First introduced by Trey and Davidson [1] in their manuscript on fulminant hepatic failure, the syndrome of ALF was recently redefined by O’Grady et al. [2] in 1993 according to the interval between the onset of jaundice and encephalopathy distinguishing hyperacute liver failure (0–7 days), ALF (8–28 days), and subacute liver failure (29–72 days).
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Sorkine, P., Abraham, R.B., Szold, O. (2001). Liver Support Systems. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2001. Yearbook of Intensive Care and Emergency Medicine 2001, vol 2001. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59467-0_50
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DOI: https://doi.org/10.1007/978-3-642-59467-0_50
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-41407-0
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