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Pathology of CNS Tumors

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Combined Modality Therapy of Central Nervous System Tumors

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

The incidence of CNS tumors is 7–10 per 100,000 (Parkin and Muir 1992). These include parenchymal tumors as well as other non-CNS intracranial lesions like meningioma. CNS tumors can be organized according to the cell of origin, location, or behavior. Consideration of metastatic lesions provides an additional criterion for organization into primary and secondary lesions. Most presentations and classifications are based on the cell of origin, including the recent classification protocols established by the World Health Organization (WHO) (Kleihues et al. 1993; Burger 1995). The bulk of this chapter is organized according to the cell of origin. The cell of origin is not known for all CNS tumors. The identity of the hemangioblastoma stromal cell, for example, is not known. The bulk of the mature central nervous system cellular population consists of neurons, astrocytes, oligodendrocytes,and ependymal cells. These are all derivatives of the primitive embryona neuroectoderm. The most common intraparenchymal neoplasms arise from the astrocyte and will be discussed first.

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Authors and Affiliations

  1. Clinical Medicine, Pathology and Neurology, USC Keck School of Medicine, McKibben Annex 346, 2011 Zonal Avenue, Los Angeles, 90033, USA

    Roscoe Atkinson

Authors
  1. Roscoe Atkinson
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Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, University of Southern California, Keck School of Medicine 1441 Eastlake Avenue, Room G356, Los Angeles, CA, 90033-0804, USA

    Zbigniew Petrovich MD, FACR (Professor and Chairman) (Professor and Chairman)

  2. Department of Radiation Oncology, Hahnemann University Hospital, Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102, USA

    Luther W. Brady MD (Hylda Cohn/ American Cancer Society Professor of Clinical Oncology and Professor) (Hylda Cohn/ American Cancer Society Professor of Clinical Oncology and Professor)

  3. Keck School of Medicine of the University of Southern California, Los Angeles, CA, 90033, USA

    Michael L. J. Apuzzo MD (Edwin M. Todd/Trent H. Wells, Jr. Professor of Neurological Surgery and Professor of Radiation Oncology) (Edwin M. Todd/Trent H. Wells, Jr. Professor of Neurological Surgery and Professor of Radiation Oncology)

  4. Department of Radiotherapy, Eberhard-Karls-Universität, Hoppe-Seyler-Strasse 3, 72076, Tübingen, Germany

    Michael Bamberg MD

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© 2003 Springer-Verlag Berlin Heidelberg

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Atkinson, R. (2003). Pathology of CNS Tumors. In: Petrovich, Z., Brady, L.W., Apuzzo, M.L.J., Bamberg, M. (eds) Combined Modality Therapy of Central Nervous System Tumors. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56411-6_2

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  • DOI: https://doi.org/10.1007/978-3-642-56411-6_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00627-5

  • Online ISBN: 978-3-642-56411-6

  • eBook Packages: Springer Book Archive

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