Zusammenfassung
Allelverlust bedeutet, dass in einer diploiden Körperzelle eines der zwei Allele, die sich an einem bestimmten Locus gegenüberliegen, verloren geht. Die Bezeichnung Allelverlust wird heute allgemein mit Verlust der Heterozygotie gleichgesetzt, obwohl die Begriffe nicht vollkommen synonym sind. International hat sich die Abkürzung LOH für loss of heterozygosity eingebürgert.
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Happle, R. (2003). Allelverlust als Erkenntnisgewinn. In: Plewig, G., Prinz, J. (eds) Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55661-6_17
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