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How Proteins Speak with One Another In Cell Signaling

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Molecular Nuclear Medicine

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Abstract

This chapter will focus on cell signaling and signal transduction, that is, the extremely complex series of reactions by which cells receive and react to external signals (for reviews, see Hunter 2000; Pawson and Nash 2000). Particularly, it will deal with those processes that are regulated by protein phosphorylation. The topic is of significance considering that approximately 15 to 20% of the entire human genome (at least 6400 genes) is devoted to the expression of the molecules implicated.

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Authors
  1. Edmond H. Fischer
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Editors and Affiliations

  1. Heinrich-Heine-University Düsseldorf, Wannental 45, 88131, Lindau, Germany

    Ludwig E. Feinendegen M.D. (Professor Emeritus Nuclear Medicine) (Professor Emeritus Nuclear Medicine)

  2. Radiology and Medicine SUNY, Stonybrook, USA

    Walton W. Shreeve M.D., Ph.D. (Professor Emeritus) (Professor Emeritus)

  3. Medical Department Brookhaven National Laboratory, Upton, NY, 11973, USA

    Walton W. Shreeve M.D., Ph.D. (Professor Emeritus) (Professor Emeritus)

  4. National Institutes of Health/Clinical Center, Bldg. 10, Rm 1C401 10 Center Drive, MSC 1180, Bethesda, MD, 20892-1180, USA

    William C. Eckelman Ph. D. (Chief PET Department) (Chief PET Department)

  5. Department of Nuclear Medicine, Sung-Ae General Hospital, Shingil-1-Dong, Youngdungpo-Gu, Seoul, 121-200, Korea

    Yong-Whee Bahk M.D., Ph.D. (Professor Emeritus (CUK) and Director) (Professor Emeritus (CUK) and Director)

  6. Nuclear Medicine and Radiation Health Sciences, The Johns Hopkins University School of Hygiene and Public Health, 615 North Wolfe Street, Baltimore, MD, 21205-2179, USA

    Henry N. Wagner Jr. M. D.

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Fischer, E.H. (2003). How Proteins Speak with One Another In Cell Signaling. In: Feinendegen, L.E., Shreeve, W.W., Eckelman, W.C., Bahk, YW., Wagner, H.N. (eds) Molecular Nuclear Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55539-8_4

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  • DOI: https://doi.org/10.1007/978-3-642-55539-8_4

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