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Atopy is the clinical manifestation of type I hypersensitivity reactions including eczema, asthma, and rhinitis. It describes a general predisposition toward development of IgE-mediated hypersensitivity reactions toward common environmental antigens. Atopic dermatitis is a chronic, itching, inflammation of the skin in atopic individuals. Contact hypersensitivity is a delayed inflammatory reaction on the skin seen in type IV hypersensitivity, resulting from allergic sensitization. Dermatitis is an inflammatory skin disease showing redness, swelling, infiltration, scaling, and sometimes vesicles and blisters. Skin irritation is a form of skin inflammation induced by primary contact with chemicals and is not mediated by lymphocytes. The skin is a physical barrier between an organism and its environment. It can be divided into four different regions: the stratum corneum, the viable epidermis, the dermis, and the hypodermis. Percutaneous absorption...
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Corsini, E. (2016). Skin, Contribution to Immunity. In: Vohr, HW. (eds) Encyclopedia of Immunotoxicology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54596-2_1356
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DOI: https://doi.org/10.1007/978-3-642-54596-2_1356
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