Abstract
Blood flow at vessel segments with complicated geometry are the objects of fluid-dynamically oriented investigations concerning atherogenesis and thrombosis [1,2]. The development of atherosclerosis in large arteries is determined by two pathogenetic factors: the integrity of the arterial wall and the contents of the vessel, e.g. platelets, white and red blood cells, cholesterol levels [11]. These factors are linked to intimai lipid accumulations and development of fibrous changes in the intima of the arterial wall. In addition, blood is a complex fluid, comprising liquid and flexible cells. How hemodynamic factors like shear stress, high and low velocity gradients, pressure gradients and mass transfer variations play a major role in atherogenesis are not yet understood [13,14], but the areas of predilection for atherosclerosis and thrombosis in the vascular system are characterized by curvature, branding, bifurcation or embanking, where laminar flow is altered and vortices, stagnation points and reverse flows are found [8].
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© 1990 Springer-Verlag Berlin Heidelberg
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Seiffge, D., Kremer, E., Laux, V., Reifert, P. (1990). Investigations Concerning Localization of Induced Thrombus Formation at Arteriolar Bifurcations. In: Liepsch, D.W. (eds) Biofluid Mechanics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-52338-0_29
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DOI: https://doi.org/10.1007/978-3-642-52338-0_29
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