Abstract
Adam et al. [1] showed that a water-soluble fraction (WSA) extracted from mycobacteria was a potent adjuvant to various antigens when added to Freund’s incomplete adjuvant (FIA). Furthermore, this substance was free of the untoward effects of whole mycobacteria: WSA did not sensitize to tuberculin, did not increase the susceptibility of mice to endotoxin nor did it induce allergic polyarthritis in rats [4]. Under certain conditions, WSA in saline also potentiated the immune response [10].
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References
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© 1974 Springer-Verlag Berlin · Heidelberg
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Bona, C., Heuclin, C., Chedid, L. (1974). Enhancement of Human Mixed-Lymphocyte Cultures by a Water-Soluble Adjuvant. In: Mathé, G., Weiner, R. (eds) Investigation and Stimulation of Immunity in Cancer Patients. Recent Results in Cancer Research, vol 47. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49284-6_27
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DOI: https://doi.org/10.1007/978-3-642-49284-6_27
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