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Juniperus Species

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Adverse Effects of Herbal Drugs 2

Part of the book series: Adverse Effects of Herbal Drugs ((HERBAL DRUGS,volume 2))

Abstract

The junipers constitute a genus of about 60 species of conifers of the family Cupressaceae growing in the northern hemisphere. The most significant species are Juniperus communis L (common juniper), J. sabina L. (savin), J. oxycedrus L. (cade) and J. virginiana L (cedarwood). According to the Flora Europaea, a number of species notably J. sabina, J. virginiana, J. excelsa, J. phoenicea and J. thurifera are sometimes classified as a separate genus Sabina Miller on morphological grounds [1].

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References

  1. Tutin TG, Heywood V, Burges NA, Valentine DH, Walters SM, Webb DA (1964) Flora Europaea Vol 1 Cambridge: Cambridge Univ Press pp 38–39

    Google Scholar 

  2. Leung AY (1980) Encyclopedia of common natural ingredients used in food, drugs and cosmetics. New York: Wiley-Interscience pp 208–209

    Google Scholar 

  3. Williamson EM, Evans FJ (1988) Potters new cyclopaedia of botanical drugs and preparations by Wren RC. Saffron Waiden: The CW Daniel Company pp 160–161

    Google Scholar 

  4. Markkanen T, Makinen ML, Nikoskelainen J, Ruhonen J, Nieminen K, Jokinen P, Raunio R, Hirvonen T (1981) Antiherpetic agent from juniper tree (Juniperus communis), its purification, identification and testing in primary human amnion cell cultures. Drugs Exptl Clin Res 7:691–697

    CAS  Google Scholar 

  5. Fitzgerald DB, Hartwell JL, Leiter J (1957) Distribution of tumor-damaging lignans among conifers. J Natl Cancer Inst 18:83–99

    PubMed  CAS  Google Scholar 

  6. Hartwell JL, Johnson JJ, Fitzgerald DB, Belkin M (1953) Podophyllotoxin from Juniperus species: Savinin. JA Chem Soc 75:235–236

    Article  CAS  Google Scholar 

  7. Serebryakova AP, Filitis LN, Utkin LM (1961) Lignans of the Soviet Union Juniperus plants. Zhur Obschei Khim 31:1731–7134 [per Chem Abstr 55:26144]

    CAS  Google Scholar 

  8. Fournier G, Pages N, Fournier L, Callen G (1990) Contribution a l’etude des huiles essentielles de differentes especes de Juniperus J Pharm Belg 45:293–298

    CAS  Google Scholar 

  9. Fournier G, Pages N, Baudron V, Paris M (1989) Étude d’echantillons commerciaux de sabine: rameaux feuilles et huille essentielle. Plantes Med Phytother 23:169–179

    CAS  Google Scholar 

  10. Fournier G, Pages N, Fournier C, Callen G (1991) Comparisons of volatile leaf essential oils of various Juniperus pfitzeriana Pharm Acta Helv 66:74–75

    CAS  Google Scholar 

  11. Simonsen, JL (1924) Constituents of some Indian essential oils XV. Essential oil from the seeds of J. communis Indian Forest Records 11:6–9 [per Chem. Abstr. 19:2723]

    CAS  Google Scholar 

  12. Leung AY (1980) Encyclopedia of common natural ingredients used in food, drugs and cosmetics. New York: Wiley Interscience pp 81–82

    Google Scholar 

  13. Leung AY (1980) Encyclopedia of common natural ingredients used in food, drugs and cosmetics. New York: Wiley-Interscience pp 105–107

    Google Scholar 

  14. Bredenberg JB (1961) The Chemistry of the Order Cupressales. 36. The ethereal oil of the wood of Juniperus communis L. Acta Chem Scand 15:961–966

    Article  CAS  Google Scholar 

  15. Adams RP (1987) Investigation of Juniperus species of the United States for new sources of cedarwood oil. Econ Bot 41:48–54

    Article  CAS  Google Scholar 

  16. Chandler RF (1986) An inconspicuous but insidious drug. Can Pharm J 119:563–566

    Google Scholar 

  17. Arzneiburo der Bundesvereinigung Deutscher Apothekerverbande. Pharmazeutische Stoffliste (1990) 7 Auflage. Frankfurt am Main: Werbe- und Vertriebsgesellschaft Deutscher Apotheker mbH. Io-L pp 12–19

    Google Scholar 

  18. Kupchan SM, Hemingway JC, Knox JR (1965) Tumour inhibitors VII. Podophyllotoxin, the active principle of Juniperus virginiana J Pharm Sci 54:659–660

    Article  PubMed  CAS  Google Scholar 

  19. Tanimami B, Torrance SJ, Cole JR (1977) Antitumour agent from Juniperus bermudiana (Pinaceae): deoxypodophyllotoxin. Phytochem 16:1100–1101

    Article  Google Scholar 

  20. Lasheras B, Turillas P, Cenarruzabeitia E (1986) Etude pharmacologique preliminaire de Prunus spinosa L, Amelanchier ovalis Medikus, Juniperus communis L. et Urtica dioica L. Plantes Med Phytother 20:219–226

    Google Scholar 

  21. Volmor H, Giebel A (1938) The diuretic action of several combinations of Juniper berry and Ononis root. Arch Exptl Path Pharmakol 190:522–534

    Article  Google Scholar 

  22. Janku I, Hava M, Motl O (1957) Ein diuretisch wirksamer stoff aus wacholder (Juniperus communis L.). Experientia 13:255–256

    Article  PubMed  CAS  Google Scholar 

  23. Janku I, Hava M, Kraus R, Motl O (1960) Das diuretische prinzip des Wacholders. Arch Exptl Pathol Pharmakol 238:112–113

    Article  CAS  Google Scholar 

  24. Mishra P, Agrawal RK (1989) Some observations on the pharmacological activities of the essential oil of Juniperus macropoda Fitoterapia 60:339–345

    Google Scholar 

  25. Opdyke DLJ (1975) Cade oil rectified (juniper tar). Fd Cosmet Toxicol 13:733–734

    Article  Google Scholar 

  26. Fedorov Yu A, Kaliberdina NV, Todorashko VP (1977) Effect of [tooth] pastes containing biologically active ingredients on the oral cavity tissues. Maslo-Zhir prom — st 1977:22. [per Chem Abstr 89:570]

    Google Scholar 

  27. Manceau P, Revol L, Vernet AM (1936) Les essences de sabine du commerce. Etude d’essences authentique de Juniperus sabina L. et de Juniperus phoenicea L. Bull Soc Pharmacol 43:14–24

    CAS  Google Scholar 

  28. Renaux J, La Barre J (1941) Sur les effets ocytociques des essences de Rue et de Sabine. Acta Biol Belg 1:334–335

    Google Scholar 

  29. Opdyke DLI (1976) Juniper Berry Oil. Fd Cosmet Toxicol 14:333

    Article  CAS  Google Scholar 

  30. Reynolds JEF (ed.) (1989) Martindale. The Extra Pharmacopoeia 29th edn. London: The Pharmaceutical Press p 917

    Google Scholar 

  31. Ministere des Affaires Sociales et de la Solidarite (France) (1990) Medicaments a base de Plantes. Avis aux fabricants concernant les demandes d’autorisation de mise sur le marche. Bulletin Officiel No. 90/22 bis

    Google Scholar 

  32. Von Skramlik E (1959) Über die Giftigkeit und Vertraglichkeit von aetherischen Ölen. Pharmazie 14:435–445

    PubMed  CAS  Google Scholar 

  33. Jenner PM, Hagan EC, Taylor JM, Cook EL, Fitzhugh OG (1964) Food flavourings and compounds of related structure 1. Acute oral toxicity. Fd Cosmet Toxicol 2:327–343

    Article  CAS  Google Scholar 

  34. Opdyke DLJ (1974) Cedarwood oil Virginia. Fd Cosmet Toxicol 12:845–846

    Article  Google Scholar 

  35. Duke JA (1985) Handbook of Medicinal Herbs. Boca Raton: CRC Press pp 256–257

    Google Scholar 

  36. Rajohn CA, Wirth E (1932) The toxicity of various preparations of Extractum Juniperi. Arch Exptl Path Pharmakol 166:222–228

    Article  Google Scholar 

  37. Flaminio Favero P, Veiga de Carvalho H, Novah E (1940) Experimental study of apiole, savin and rue. Anais Faculdade Med Univ S Paulo 16:499–523

    Google Scholar 

  38. Patoir A, Patoir G, Bedrine H (1938) Action toxique de l’essence de sabine et de l’armoise sur l’organisme. Compt Rend Soc Biol 127:1325–1326

    CAS  Google Scholar 

  39. Revol L (1935) Juniperus thurifera and its essence. Bull Sci Pharmacol 42:577–589

    CAS  Google Scholar 

  40. Mitchell J, Rook A (1979) Botanical Dermatology. Vancouver: Greengrass pp 242–244

    Google Scholar 

  41. Katz AE (1946) Dermal irritating properties of essential oils and aromatic chemicals. Spice Mill 69:46–7, 50–51 [per Chem Abstr 40:7525]

    CAS  Google Scholar 

  42. Bouhlal K, Meynadier J-M, Peyron J-L, Peyron L, Marion J-P, Bonetti G, Meynadier J (1988) Le Cade en dermatologie. Parfums, Cosmet Aromes 83:73–82

    CAS  Google Scholar 

  43. Wade A (ed) (1977) Martindale the extra Pharmacopoeia, 27th edn. London: The Pharmaceutical Press, p 1026

    Google Scholar 

  44. Revol L (1936) L’essence constitute t-elle l’unique principe actif des Juniperus de la section Sabina? Action physiologique d’extraits de J. sabina, J. phoenicea, J. thurifera Bull Soc Pharmacol 43:139–144

    CAS  Google Scholar 

  45. Papavassiliou MJ (1935) Sur deux cas d’intoxication par la Sabine. La permeabilite placentaire a l’essence de sabine. Soc Med Leg 15:778–781

    CAS  Google Scholar 

  46. British Herbal Pharmacopoeia (1983) Bournemouth: British Herbal Medicine Association, p 124

    Google Scholar 

  47. Anonymous (1984) Monograph der Kommission E: Bundesanzeiger Nummer 228 vom 05–12–1984

    Google Scholar 

  48. Czygan F-C (1987) Warning vor unkritischem gebrauch von Wacholderbeeren. Z Phytotherapie 8:10

    Google Scholar 

  49. Schilcher H (1985) Effects and side-effects of essential oils. In: Essential oils and aromatic plants (ed Baerheim Svendsen A, Scheffer JJC) Dordrecht: Martinus Nijhoff, pp 226, 288, 299

    Google Scholar 

  50. Blumel P (1941/1943) Blutharnen bei Vergiftung mit Sadebaumspitzen. Vergiftungsfälle 12:25–28

    Article  Google Scholar 

  51. Wade AE, Hall JE, Hilliard CC, Molton E, Greene FL (1968) Alteration of drug metabolism in rats and mice by an environment of cedarwood. Pharmacology 1:317–328

    Article  PubMed  CAS  Google Scholar 

  52. Prakash AO (1986) Potentialities of some indigenous plants for antifertility activity. Int J Crude Drug Res 24:19–24

    CAS  Google Scholar 

  53. Prochnow L (1912) Experimental contribution to the study of popular abortifacients. Arch Intern Pharmacodyn 21:313–319 [per Chem Abstr (1912) 6:1181]

    CAS  Google Scholar 

  54. Macht DI (1912) The action of so-called emmenagogue oils. J Pharmac 4:547–552 [per Chem Abstr (1913) 7:3367]

    Google Scholar 

  55. USP Dispensing Information (1986) Vol. 1. Drug information for the health care provider. 6th edn. United States Pharmacopoeial Convention p 928

    Google Scholar 

  56. Pages N, Fournier G, Chamorro G, Salazar M, Paris M, Boudene C (1989) Teratological evaluation of Juniperus sabina essential oil in mice. Planta Medica 55:144–146

    Article  PubMed  CAS  Google Scholar 

  57. Pages N, Salazar M, Chamorro G, Fournier G, Paris M, Dumitresco SM, Boudene C (1988) Teratological evaluation of Plectranthus fruticosus leaf essential oil. Planta Medica 54:296–298

    Article  PubMed  CAS  Google Scholar 

  58. Pages N, Fournier G, LeLuyer F, Marques M-C, Boudene C (1989) Les echantillons commerciaux de “Sabine” (rameaux feuilles et huile essentielle). Sont-ils teratogenes? Etude chez la souris. Plantes Med Phytother 23:186–192

    Google Scholar 

  59. Roe RJC, Field WEM (1965) Chronic toxicity of essential oils and certain other products of natural origin. Fd Cosmet Toxicol 3:311–324

    Article  CAS  Google Scholar 

  60. Fabian F, Poliniceucu M (1985) Study on the content of aromatic polycyclic hydrocarbons of some pharmaceuticals. Farmacia (Bucharest) 33:117–122 [per Chem Abstr. 104:56487]

    CAS  Google Scholar 

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Authors
  1. D. Corrigan
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Editors and Affiliations

  1. Drug Information Center, Royal Dutch Association for the Advancement of Pharmacy, Alexanderstraat 11, 2514 JL, The Hague, The Netherlands

    Peter A. G. M. De Smet

  2. Institut für Arzneimittel des Bundesgesundheitsamtes, Seestraße 10, 13353, Berlin, Germany

    Konstantin Keller

  3. Westpreußenstraße 71, 81927, München, Germany

    Rudolf Hänsel

  4. College of Pharmacy, Dalhousie University, Halifax, B3H 3J5, Canada

    R. Frank Chandler

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© 1993 Springer-Verlag Berlin Heidelberg

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Corrigan, D. (1993). Juniperus Species. In: De Smet, P.A.G.M., Keller, K., Hänsel, R., Chandler, R.F. (eds) Adverse Effects of Herbal Drugs 2. Adverse Effects of Herbal Drugs, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48906-8_16

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  • DOI: https://doi.org/10.1007/978-3-642-48906-8_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-55800-2

  • Online ISBN: 978-3-642-48906-8

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