Abstract
Electric stimulation has been widely used to induce changes in neuronal cultures coupled to microelectrode arrays (MEAs). In this paper, we used different electrical stimulation protocols on dissociated cultures of hippocampal cells for studying the electrical properties of the process. We show that persistent and synchronous stimulation of adjacent electrodes may be used for creating adjacent physical or logical connections in the connectivity graph following Hebb’s Law modifying the neural responses principal parameters.
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Lorente, V. et al. (2013). Neural Spike Activation in Hippocampal Cultures Using Hebbian Electrical Stimulation. In: Ferrández Vicente, J.M., Álvarez Sánchez, J.R., de la Paz López, F., Toledo Moreo, F.J. (eds) Natural and Artificial Models in Computation and Biology. IWINAC 2013. Lecture Notes in Computer Science, vol 7930. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38637-4_5
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DOI: https://doi.org/10.1007/978-3-642-38637-4_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-38636-7
Online ISBN: 978-3-642-38637-4
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