Abstract
Pain and other short- and long-term sequelae of irreparable meniscal tears remain a challenge for the orthopedic community, and there is a genuine need for an approach which will offer patients and surgeons new acceptable treatment options (Gilbert and Ashwood, Trauma 9:189–194, 2007).
Orteq Ltd. (London, UK) has developed a polyurethane scaffold, Actifit® (Welsing et al., Am J Sports Med 36:1978-1989, 2008), for blood vessel ingrowth and meniscal tissue regeneration (Tienen et al., Am J Sports Med 34:64-71, 2006) intended for the treatment of irreparable, painful meniscus tears and meniscal tissue defects. It is available in the medial and lateral configurations (Fig. 1). Criteria for use include an intact meniscal rim and sufficient tissue in the anterior and posterior horns to permit fixation of the scaffold. Other requirements include a well-aligned and stable knee joint, an ICRS classification grade ≤3, a body mass index <35 kg/m2, and the non-presence of systemic disease or infection sequelae (Arnosky andWarren, Am J Sports Med 10:90–95, 1982).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Arnoczky SP, Warren RF (1982) Microvasculature of the human meniscus. Am J Sports Med 10:90–95
De Coninck T, Huysse W, Verdonk P et al (2013a) Open versus arthroscopic meniscus allograft transplantation: magnetic resonance imaging study of meniscal radial displacement. Arthroscopy 29(3):514–521. doi:10.1016/j.arthro.2012.10.029
De Coninck T, Huysse W, Verdonk P et al (2013b) Two-year follow-up study on clinical and radiological outcomes of polyurethane meniscal scaffolds. Am J Sports Med 41(1):64–72
Gilbert R, Ashwood N (2007) Meniscal repair and replacement: a review of efficacy. Trauma 9:189–194
Hardeman F, Corten K, Verdonk P et al (2013) What is the best way to fix a polyurethane meniscal scaffold? A biomechanical evaluation of different fixation modes. Knee Surg Sports Traumatol Arthrosc. [Epub ahead of print]
Maher SA, Doty SB, Rosenblatt L et al (2009) Evaluation of a meniscal repair scaffold in an ovine model. Poster presented at the 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, 22–25 February 2009
Tienen TG, Heijkants RG, de Groot JH et al (2006) Replacement of the knee meniscus by a porous polymer implant: a study in dogs. Am J Sports Med 34:64–71
Verdonk PCM, Van Laer MEE, Verdonk R (2008) Meniscus replacement: from allograft to tissue engineering. Sports Orthop Traumatol 24:78–82
Verdonk P, Beaufils P, Verdonk R, Actifit Study Group et al (2012) Successful treatment of painful irreparable partial meniscal defects with a polyurethane scaffold: two-year safety and clinical outcomes. Am J Sports Med 40(4):844–853
Welsing RT, van Tienen TG, Ramrattan N et al (2008) Effect on tissue differentiation and articular cartilage degradation of a polymer meniscus implant: a 2-year follow-up study in dogs. Am J Sports Med 36:1978–1989
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer-Verlag Berlin Heidelberg
About this entry
Cite this entry
Verdonk, R., Verdonk, P., Heinrichs, E.L. (2015). Meniscal Substitutes: Polyurethane Meniscus Implant: Technique and Results. In: Doral, M.N., Karlsson, J. (eds) Sports Injuries. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36569-0_75
Download citation
DOI: https://doi.org/10.1007/978-3-642-36569-0_75
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-36568-3
Online ISBN: 978-3-642-36569-0
eBook Packages: MedicineReference Module Medicine