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Aspirin: Usage, Effects, and Dosage in Ophthalmology

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Encyclopedia of Ophthalmology

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Definition

Acetylsalicylic acid.

Indication

Aspirin is used as an anticoagulant in patients with thromboembolic risk factors. Moreover, aspirin is used as an analgesic, antipyretic, and anti-inflammatory drug.

Contraindication

Allergy or intolerance to nonsteroidal anti-inflammatory drugs, gastric ulcers, liver and kidney disease, gout, hyperuricemia, glucose-6-phosphate dehydrogenase deficiency, pregnancy, and asthma.

Use and Dosage

Analgesia and antipyretic effect, 300–1,000 mg one to three times daily; anticoagulant, 75–300 mg 1/daily.

Adverse Reactions

Patients under aspirin therapy in theory have an increased risk for hemorrhagic complications when ophthalmic surgeries are performed. However, several studies have shown that vitreoretinal surgeries, cataract surgeries, glaucoma surgeries, and intravitreal injections on systemically anticoagulated patients were not associated with significant intraoperative or postoperative bleeding complications. In patients with diabetic...

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Further Reading

  • Alwitry A, King AJ, Vernon SA (2008) Anticoagulation therapy in glaucoma surgery. Graefes Arch Clin Exp Ophthalmol 246(6):891–896

    Article  CAS  PubMed  Google Scholar 

  • Chew EY, Klein ML, Murphy RP, Remaley NA, Ferris FL 3rd (1995) Effects of aspirin on vitreous/preretinal hemorrhage in patients with diabetes mellitus. Early treatment diabetic retinopathy study report no. 20. Arch Ophthalmol 113(1):52–55

    Article  CAS  PubMed  Google Scholar 

  • Kobayashi H (2010) Evaluation of the need to discontinue antiplatelet and anticoagulant medications before cataract surgery. J Cataract Refract Surg 36(7):1115–1119

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  • Mason JO 3rd, Frederick PA, Neimkin MG, White MF Jr, Feist RM, Thomley ML, Albert MA Jr (2010) Incidence of hemorrhagic complications after intravitreal bevacizumab (avastin) or ranibizumab (lucentis) injections on systemically anticoagulated patients. Retina 30(9):1386–1389

    Article  PubMed  Google Scholar 

  • Narendran N, Williamson TH (2003) The effects of aspirin and warfarin therapy on haemorrhage in vitreoretinal surgery. Acta Ophthalmol Scand 81(1):38–40

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, University of Regensburg Medical Center, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany

    Wolfgang Herrmann

  2. Department of Ophthalmology, Goethe-Universität Frankfurt, 60590, Frankfurt/Main, Germany

    Thomas Kohnen

Authors
  1. Wolfgang Herrmann
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  2. Thomas Kohnen
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Corresponding author

Correspondence to Wolfgang Herrmann .

Editor information

Editors and Affiliations

  1. Dept of Ophthal & Optometry,AKH, Medical University of Wien Dept of Ophthal & Optometry,AKH, Wien, Austria

    Ursula Schmidt-Erfurth

  2. Department of Ophthalmology, Goethe University of Frankfurt am Main Department of Ophthalmology, Frankfurt am Main, Germany

    Thomas Kohnen

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© 2012 Springer-Verlag Berlin Heidelberg

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Herrmann, W., Kohnen, T. (2012). Aspirin: Usage, Effects, and Dosage in Ophthalmology. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_330-4

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  • DOI: https://doi.org/10.1007/978-3-642-35951-4_330-4

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-35951-4

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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