Abstract
Diabetic foot problems remain a serious problem, occupying a substantial number of bed days in hospital and accounting for over 80 % non-traumatic amputations. A multidisciplinary team approach is essential for the management of these problems. Ulceration occurs because of the twin complications of neuropathy and ischaemia. Loss of sensation is the permissive factor allowing ulceration. Establishing the aetiology of the ulceration, and whether any deep infection is present, allows management along the correct pathway. The core of treatment is non-operative with operative treatment reserved for deep infection and recurrent ulceration in the presence of fixed deformity. The Charcot foot represents a particular challenge with the extent of swelling and deformity which occurs. Protective footwear and insoles are essential to prevent re-ulceration which can still occur.
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References
Andersen H, Mogensen PH. Disordered mobility of large joints in association with neuropathy in patients with long-standing insulin-dependent diabetes mellitus. Diabet Med. 1996;14:221–7.
Armstrong DG, Stern S, Lavery LA, Harkless LB. Is prophylactic diabetic foot surgery dangerous? J Foot Ankle Surg. 1996;35(6):585–9.
Armstrong DG, Peters EJ, Athanasiou KA, Lavery LA. Is there a critical level of plantar foot pressure to identify patients at risk for neuropathic foot ulceration? J Foot Ankle Surg. 1998;37(4):303–7.
Baumhauer JF, Fraga CJ, Gould JS, Johnson JE. Total calcanectomy for the treatment of chronic calcaneal osteomyelitis. Foot Ankle Int. 1998;19(12):849–55.
Bell-Krotoski J, Tomancik E. The repeatability of testing with Semmes-Weinstein monofilaments. J Hand Surg. 1987;12A:155–61.
Berendt AR, Peters EJ, Bakker K, Embil JM, Eneroth M, Hinchliffe RJ, Jeffcoate WJ, Lipsky BA, Senneville E, Teh J, Valk GD. Diabetic foot osteomyelitis: a progress report on diagnosis and a systematic review of treatment. Diabetes Metab Res Rev. 2008;24:S145–61.
Birke JA, Sims DS. Plantar sensory threshold in the ulcerative foot. Lepr Rev. 1986;57:261–7.
Bollinger M, Thordarson DB. Partial calcanectomy: an alternative to below knee amputation. Foot Ankle Int. 2002;23(10):927–32.
Boulton AJM, Kubrusly DB, Bowker JH, Gadia MT, Quintero L, Becker DM, Skyler JS, et al. Impaired vibratory perception and diabetic foot ulceration. Diabet Med. 1986;3:335–7.
Boulton AJM, Malik RA, Arezzo JC, Sosenko JM. Diabetic somatic neuropathies: technical review. Diabetes Care. 2004;27:1458–86.
Brand PW. Repetitive stress in the development of diabetic foot ulcers. In: Levin ME, O’Neal LW, editors. The diabetic foot. St Louis: CV Mosby; 1988. p. 83–90.
Brodsky J, Kwong P, Wagner F, et al. Patterns of breakdown, natural history and treatment of the diabetic Charcot tarsus. Orthop Trans. 1987;11:484.
Cavanagh PR, Ulbrecht JS, Caputo GM. Elevated plantar pressure and ulceration in diabetic patients after panmetatarsal head resection: two case reports. Foot Ankle Int. 1999;20(8):521–6.
Charcot JM. Sur quelques arthropathies qui paraissent dependre d’une lesion du cerveau ou de la moelle epiniere. Arch Physiol Norm Pathol. 1868;1:161–78.
Coleman WC, Brand PW, Birke JA. The total contact cast. A therapy for plantar ulceration on insensitive feet. J Am Podiatr Med Assoc. 1984;74(11):548–52.
Connor H. The economic impact of diabetic foot disease. In: Connor H, Boulton AJM, Ward JD, editors. The foot in diabetes. Chichester: Wiley; 1987. p. 145–9.
Conte MS. Challenges of distal bypass surgery in patients with diabetes: patient selection, techniques and outcomes. J Vasc Surg. 2010;52:S96–103.
Crerand S, Dolan M, Laing P, Bird M, Smith ML, Klenerman L. Diagnosis of osteomyelitis in neuropathic foot ulcers. J Bone Joint Surg Br. 1996;78(1):51–5.
Dalla Paola L, Brocco E, Ceccacci T, Ninkovic S, Sorgentone S, Marinescu MG, Volpe A. Limb salvage in Charcot foot and ankle osteomyelitis: combined use single stage/double stage of arthrodesis and external fixation. Foot Ankle Int. 2009;30(11):1065–70.
Davidson JK, Alogna M, Goldsmith M, Borden J. Assessment of program effectiveness at Grady memorial hospital, Atlanta. In: Steiner G, Lawrence PA, editors. Educating diabetic patients. New York: Springer; 1981. p. 329–48.
Dayer R, Assal M. Chronic diabetic ulcers under the first metatarsal head treated by staged tendon balancing. J Bone Joint Surg Br. 2009;91(4):487–93.
Driver VR, Fabbi M, Lavery LA, Gibbons G. The costs of diabetic foot: the economic case for the limb salvage team. J Vasc Surg. 2010;52:S17–22.
Edmonds ME, Blundell MP, Morris ME, Maelor Thomas E, Cotton LT, Watkins PJ. Improved survival of the diabetic foot: the role of a specialised foot clinic. Q J Med. 1986;232:763–71.
Eichenholtz SN. Charcot joints. Springfield: CC Thomas; 1966. p. 1–20.
Falstie-Jensen N, Christensen KS, Brochner-Mortensen J. Long posterior flap versus equal sagittal flaps in below-knee amputation for ischaemia. J Bone Joint Surg Br. 1989;71(1):102–4.
Ferraresi R, Centola M, Ferlini M, Da Ros R, Caravaggi C, Assaloni R, Sganzaroli A, Pomidossi G, Bonanomi C, Danzi GB. Long-term outcomes after angioplasty of isolated, below-the-knee arteries in diabetic patients with critical limb ischaemia. Eur J Vasc Endovasc Surg. 2009;37(3):336–42.
Frykberg RG. Charcot foot: an update on pathogenesis and management. In: Bolton AJM, Connor H, Cavanagh PR, editors. The foot in diabetes. Chichester: Wiley; 2000. p. 235–60.
Game FL, Jeffcoate WJ. Primarily non-surgical management of osteomyelitis of the foot in diabetes. Diabetologia. 2008;51(6):962–7.
Gibbons GW, Eliopoulos GM. Infection of the diabetic foot. In: Kozak GP, Campbell DR, Frykberg RG, Habershaw GM, editors. Management of diabetic foot problems. 2nd ed. Philadelphia: WB Saunders; 1995. p. 121–9.
Giurini JM, Basile P, Chrzan JS, Habershaw GM, Rosenblum BI. Panmetatarsal head resection. A viable alternative to the transmetatarsal amputation. J Am Podiatr Med Assoc. 1993;83(2):101–7.
Goebel FD, Fuessl HS. Monckeberg’s sclerosis after sympathetic denervation in diabetic and non-diabetic subjects. Diabetologia. 1983;24(5):347–50.
Gordois A, Suffham P, Shearer A, Oglesby A, Tobian JA. The health care costs of diabetic peripheral neuropathy in the US Diabetes Care. Diabetes care. 2003;26:1790–5.
Griffiths GD, Wieman TJ. Metatarsal head resection for diabetic foot ulcers. Arch Surg. 1990;125(7):832–5.
Van Ha G, Siney H, Danan JP, Sachon C, Grimaldi A. Treatment of osteomyelitis in the diabetic foot. Contribution of conservative surgery. Diabetes Care. 1996;19(11):1257–60.
Holstein P, Lohmann M, Bitsch M, Jorgensen B. Achilles tendon lengthening, the panacea for plantar forefoot ulceration? Diabetes Metab Res Rev. 2004;20 Suppl 1:S37–40.
International Diabetes Federation. IDF Diabetes Atlas, 4th edition at www.diabetesatlas.org.
Jordan WR. Neuritic manifestations in diabetes mellitus. Arch Intern Med. 1936;57:307–58.
Jude EB, Selby PL, Burgess J, Lilleystone P, Mawer EB, Page SR, Donohoe M, Foster AV, Edmonds ME, Boulton AJ. Bisphosphonates in the treatment of Charcot neuroarthopathy: a double blind, randomised, controlled trial. Diabetologia. 2001;44(11):2032–7.
Kalish J, Hamdan A. Management of diabetic foot problems. J Vasc Surg. 2010;51(2):476–86.
Kapelrud H. Lower-limb amputations and diabetes. Tidsskr Nor Laegeforen. 2006;126(17):2261–3.
Khan JS. Treatment of leprous trophic ulcers. Lepr India. 1939;11:19.
Klenerman L, McCabe C, Cogley D, Crerand S, Laing P, White M. Screening for patients at risk of diabetic foot ulceration in a general diabetic outpatient clinic. Diabet Med. 1996;13:561–3.
Laing PW, Cogley DI, Klenerman L. Neuropathic foot ulceration treated by total contact casts. J Bone Joint Surg Br. 1992;74(1):133–6.
Lavery LA, Armstrong DG, Vela SA, Quebedeaux TL, Fleischli JG. Practical criteria for screening patients at high risk for diabetic foot ulceration: a prospective study. Arch Intern Med. 1998;158(2):157–62.
Levin ME, O’Neal LW. The diabetic foot. St. Louis: CV Mosby; 1988.
Lipsky BA, Osteomyelitis of the Foot in Diabetic Patients. Clinical Infectious Diseases 1997;25:1318–26.
Massó González EL, Johansson S, Wallander M-A, García Rodríguez LA. Trends in the prevalence and incidence of diabetes in the UK: 1996–2005. J Epidemiol Community Health. 2009;63:332–6.
Mayfield JA, Reiber GE, Sanders LJ, Janisse D, Pogach LM. Preventive foot care in diabetes. Diabetes Care. 2004;27:S63–4.
Meggitt B. Surgical management of the diabetic foot. Br J Hosp Med (Lond). 1976;16:227–32.
Mitchell JK. On a new practice in acute and chronic rheumatism. Am J Med Sci. 1831;8:55–64.
Mittlmeier T, Klaue K, Haar P, Beck M. Should one consider primary surgical reconstruction in Charcot arthopathy of the feet? Clin Orthop Relat Res. 2010;468:1002–11.
Morales Lozano R, Gonzalez Fernandez ML, Martinez Hernandez D, Beneit Montesinos JV, Guisado Jimenez S, Gonzalez Jurado MA. Validating the probe-to-bone test and other tests for diagnosing chronic osteomyelitis in the diabetic foot. Diabetes Care. 2010;33(10):2140–5.
Mueller MJ, Sinacore DR, Hastings MK, Strube MJ, Johnson JE. Effect of Achilles tendon lengthening on neuropathic plantar ulcers a randomised clinical trial. J Bone Joint Surg Am. 2003;85-A(8):1436–45.
Murdoch DP, Armstrong DG, Dacus JB, Laughlin TJ, Morgan CB, Lavery LA. The natural history of great toe amputations. J Foot Ankle Surg. 1997;36(3):204–8.
Myerson M. Salvage of diabetic neuropathic arthropathy with arthrodesis. In: Helal B, Rowley DI, Cracchiolo A, Myerson M, editors. Surgery of disorders of the foot and ankle. London: Martin Dunitz; 1996. p. 513–22.
Nather A, Chionh SB, Han AY, Chan PP, Nambiar A. Effectiveness of vacuum-assisted closure (VAC) therapy in the healing of chronic diabetic foot ulcers. Ann Acad Med Singapore. 2010;39(5):353–8.
O‘Connor BL, Palmoski MJ, Brandt KD. Neurogenic acceleration of degenerative joint lesions. J Bone Joint Surg Am. 1985;67(4):562–72.
Papa J, Myerson M, Girard P. Salvage, with arthrodesis, in intractable diabetic neuropathic arthropathy of the foot and ankle. J Bone Joint Surg Am. 1993; 75-A:1056–66.
Pecoraro RE, Reiber GE, Burgess EM. Casual pathways to amputation: basis for prevention. Diabetes Care. 1990;13:513–21.
Petrov O, Pfeifer M, Flood M. Recurrent plantar ulceration following pan metatarsal head resection. J Foot Ankle Surg. 1996;35(6):573–7.
Pinzur MS. Restoration of walking ability with Syme’s ankle disarticulation. Clin Orthop. 1999; 361:71–5.
Pirart J. Diabetes mellitus and its degenerative complications, a prospective study of 4400 patients observed between 1947 and 1973. Diabetes Care. 1978;I:168–88 and 252–263.
Poirier JY, Garin E, Derrien C, Devillers A, Moisan A, Bourguet P, Maugendre D. Diagnosis of osteomyelitis in the diabetic foot with a 99mTc-HMPAO leucocyte scintigraphy combined with a 99mTc-MDP bone scintigraphy. Diabetes Metab. 2002;28:485–90.
Pollard JP, Le Quesne LP. Method of healing diabetic forefoot ulcers. Br Med J Clin Res. 1983; 286(6363):436–7.
Quebedeaux TL, Lavery DC, Lavery LA. The development of foot deformities and ulcers after great toe amputation in diabetes. Diabetes Care. 1996;19(2):165–7.
Simon SR, Tejwani SG, Wilson DL, Santner TJ, Denniston NL. Arthrodesis as an early alternative to nonoperative management of Charcot arthropathy of the diabetic foot. J Bone Joint Surg Am. 2000; 82:939–50.
Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. JAMA. 2005; 293:217–28.
Spencer F, Sage R, Graner J. The incidence of foot pathology in a diabetic population. J Am Podiatr Med Assoc. 1985;75:590–2.
Veves A, Murray HJ, Young MJ, Boulton AJ. The risk of foot ulceration in diabetic patients with high foot pressure: a prospective study. Diabetologia. 1992;35(7):660–3.
Wagner FW. The dysvascular foot: a system for diagnosis and treatment. Foot Ankle. 1981;2(2):64–122.
Waters RL, Perry J, Antonelli D, Hislop H. Energy costs of walking of amputees: the influence of level of amputation. J Bone Joint Surg Am. 1976;58(1):42–6.
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Laing, P. (2014). The Diabetic Foot. In: Bentley, G. (eds) European Surgical Orthopaedics and Traumatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34746-7_150
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