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Animal Model to Investigate the Role of the Motor Cortex during Treadmill Locomotion in Rats

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Converging Clinical and Engineering Research on Neurorehabilitation

Part of the book series: Biosystems & Biorobotics ((BIOSYSROB,volume 1))

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Abstract

The objective of the present workwas to develop an animal model to assess information on how the motor cortex encodes gait. Two Sprague-Dawley rats were chronically implanted with a 16 channel micro-wire array in the primary motor cortex (M1) and two intramuscular fine wire EMG electrodes (bipolar) in two hindlimb muscles. Over five days, intra-cortical signals (IC) and EMG data were recorded simultaneously with high-speed videography while the rat performed locomotion on a horizontal and inclined (15.) treadmill. Preliminary results prove the functionality of the model and the possibility to assess information on how the brain encodes gait.

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© 2013 Springer-Verlag Berlin Heidelberg

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Routhe, J.S., Niemeier, M.J., Riis, H.C., Schneider, G., Jensen, W. (2013). Animal Model to Investigate the Role of the Motor Cortex during Treadmill Locomotion in Rats. In: Pons, J., Torricelli, D., Pajaro, M. (eds) Converging Clinical and Engineering Research on Neurorehabilitation. Biosystems & Biorobotics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34546-3_53

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  • DOI: https://doi.org/10.1007/978-3-642-34546-3_53

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-34545-6

  • Online ISBN: 978-3-642-34546-3

  • eBook Packages: EngineeringEngineering (R0)

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