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DNA-DNA Origami

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Encyclopedia of Polymeric Nanomaterials

Synonyms

DNA nanostructure

Definition

DNA origami is a two- or three-dimensional nanostructure of custom shape utilizing hundreds of short “staple” single DNA strands to sew a long “scaffold” single DNA strand.

Introduction to DNA Origami

DNA, a genetic information carrier in nature, has been used as natural materials to build complex two- to three- dimensional structures at the nanometer scale. Watson-Crick base pairing rule between DNA bases where adenine (A) and guanine (G) form hydrogen bonds with thymine (T) and cytosine (C), respectively, allows to program diverse structural DNA motifs. The original idea was proposed by Seeman in 1982 [1] and was further evolved to DNA origami concept by Rothemund in 2006 [2], and now the relevant technology was termed as DNA nanotechnology. The DNA origami utilizes hundreds of short “staple” single strands with length of typically 20–50 nucleotides to sew a long “scaffold” single strand folding into two-dimensional structures of custom shape as...

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Author information

Authors and Affiliations

  1. Department of Micro Engineering, Graduate School of Engineering, Kyoto University, Yoshidahonmachi, 606-8501, Kyoto, Japan

    Zhipeng Ma & Osamu Tabata

  2. Department of Mechanical and Aerospace Engineering, Seoul National University, 1, Gwanak-ro, 151-744, Gwanak-gu, Seoul, South Korea

    Young-Joo Kim & Do-Nyun Kim

Authors
  1. Zhipeng Ma
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  2. Young-Joo Kim
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  3. Do-Nyun Kim
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  4. Osamu Tabata
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Corresponding author

Correspondence to Zhipeng Ma .

Editor information

Editors and Affiliations

  1. Center for Fiber and Textile Science, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto, Japan

    Shiro Kobayashi

  2. Max Planck Institute for Polymer Research, Mainz, Germany

    Klaus Müllen

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Ma, Z., Kim, YJ., Kim, DN., Tabata, O. (2015). DNA-DNA Origami. In: Kobayashi, S., Müllen, K. (eds) Encyclopedia of Polymeric Nanomaterials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29648-2_321

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