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Traumatic Brain Injury, Neurological/Psychiatric Issues

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Encyclopedia of Trauma Care
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Synonyms

Affective changes; Dizziness; Posttraumatic epilepsy; Posttraumatic headache

Definition

TBI survivors suffer from a variety of neurological and psychiatric problems after their traumatic event, often ultimately leading to significant disability and caregiver burden (Kraus et al. 1984). Improved medical interventions and a higher incidence in younger populations have led to much longer lifespans as well for these individuals, creating a great need for improved understanding of long-term outcomes and effective long-term treatment modalities (Colantonio et al. 2004; Cope et al. 2012). The pressing cognitive issues seen in the post TBI period and the currently employed rehabilitation techniques have been described in other sections. In this section, we will focus on other neurological complications, psychiatric concerns, and potential treatment options for these issues.

Neurological Issues

The range of neurological complications for TBI survivors encompasses dizziness, seizures,...

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References

  • Albera R, Ciufflotti R, Di Cicco M et al (2003) Double-blind, randomized, multicenter study comparing the effect of betahistine and flunarizine on the dizziness handicap in patients with recurrent vestibular vertigo. Aca Otolaryngol 123:588–593

    Article  CAS  Google Scholar 

  • Alsalaheen B, Mucha A, Morris L et al (2010) Vestibular rehabilitation for dizziness and balance disorders after concussion. JNPT 34:87–93

    PubMed  Google Scholar 

  • Annegars JF, Hauser WA, Coan SP et al (1998) A population based study of seizures after traumatic brain injuries. N Engl J Med 338:20–24

    Article  Google Scholar 

  • Ashman TA, Spielman LA, Hibbard MR et al (2004) Psychiatric challenges in the first 6 years after traumatic brain injury: cross-sequential analyses of axis 1 disorders. Arch Phys Med Rehabil 85:S36–S42

    Article  PubMed  Google Scholar 

  • Ashmann TA, Cantor JB, Spielman L et al (2009) A randomized controlled trial of sertraline for the treatment of depression in persons with traumatic brain injury. Arch Phys Med Rehabil 90:733–740

    Article  Google Scholar 

  • Bourdon KH, Rae DS, Locke BZ et al (1992) Estimating the prevalence of mental disorders in US adults from the epidemiologic catchment area survey. Public Health Rep 107:663–668

    CAS  PubMed  PubMed Central  Google Scholar 

  • Chen CP, Johnston KM, Petrides M et al (2008) Neural substrates of symptoms of depression following concussion in male athletes with persisting postconcussion symptoms. Arch Gen Psychiatry 65:81–89

    Article  PubMed  Google Scholar 

  • Christensen B, Ross T, Kotasek R et al (1994) The role of depression in rehabilitation outcomes in the acute recovery of patients with TBI. Adv Med Psychother 7:23–28

    Google Scholar 

  • Colantonio A, Ratcliff G, Chase S, Kelsey S et al (2004) Long term outcomes after moderate to severe traumatic brain injury. Disabil Rehabil 26(5):253–261

    Article  CAS  PubMed  Google Scholar 

  • Colantonio A, Ratcliff G, Chase S, Vernich L (2008) Aging with traumatic brain injury. Brain Inj 22:381–386

    Article  Google Scholar 

  • Cope E, Morris D, Levenson C (2012) Improving treatments and outcomes: an emerging role for zinc in traumatic brain injury. Nutr Rev 70(7):410–413

    Article  PubMed  PubMed Central  Google Scholar 

  • Crooks C, Zumsteg J, Bell K (2007) Traumatic brain injury: a review of practice management and recent advances. Phy Med Rehabil Clin N Am 18:681–710

    Article  Google Scholar 

  • Ellis TL (2011) Dystonia and the role of deep brain stimulation. ISRN Surg. ISRN Surg 2011; 2011:193718. doi: 10.5402/2011/193718. Epub 2011 Apr 13

    Google Scholar 

  • Evans RW (2006) The postconcussion syndrome and the sequelae of mild head injury. In: Neurology and trauma, 2nd edn. Oxford University Press, New York, Print

    Google Scholar 

  • Fahn S, Jankovic J (2007) Principles and practice of movement disorders. Churchill Livingstone Elsevier, Philadelphia, Print

    Google Scholar 

  • Fann J, Katon W, Uomoto J et al (1995) Psychiatric disorders and functional disability in outpatients with traumatic brain injury. Am J Psychiatry 152(10):1493–1498

    Article  CAS  PubMed  Google Scholar 

  • Fann J, Hart T, Schomer K (2009) Treatment for depression after traumatic brain injury: a systematic review. J Neurotrauma 36:2383–2402

    Article  Google Scholar 

  • Fedoroff JP, Starkstein S, Forrester A et al (1992) Depression in patients with acute traumatic brain injury. Am J Psychiatry 149:7

    Article  Google Scholar 

  • Fogelberg D, Hoffman J, Dikmen S et al (2012) Association of sleep and co-occurring psychological conditions at 1 year after traumatic brain injury. Arch Phys Med Rehabil 93(8):1313–1318

    Article  PubMed  Google Scholar 

  • Frei K, Pathak M, Jenkins S et al (2004) Natural history of posttraumatic cervical dystonia. Mov Disord 19(12):1492–1498

    Article  PubMed  Google Scholar 

  • Gladstone J (2009) From psychoneurosis to ICHD-2: an overview of the state of the art in post-traumatic headache. Headache 49:1097–1111

    Article  PubMed  Google Scholar 

  • Glaesser J, Neuner F, Lutgehetmann R et al (2004) Posttraumatic stress disorder in patients with traumatic brain injury. BMC Psychiatry 4:5

    Article  PubMed  PubMed Central  Google Scholar 

  • Gordon WA, Zafonte R, Cicerone K et al (2006) Traumatic brain injury rehabilitation: state of the science. Am J Phys Med Rehabil 85(4):343–382

    Article  PubMed  Google Scholar 

  • Greenwald B, Kapoor N, Singh A (2012) Visual impairments in the first year after traumatic head injury. Brain Inj 26(11):1338–1359

    Article  PubMed  Google Scholar 

  • Guillamondegui O, Montgomery S, Phibbs F et al (2011) Traumatic brain injury and depression. Rockville (MD): Agency for Healthcare Research and Quality. Report No.: 11-EHC017-EF

    Google Scholar 

  • Hanks R, Temkin N, Machomer J et al (1999) Emotional and behavioral adjustment after traumatic brain injury. Arch Phys Med Rehabil 80:991–997

    Article  CAS  PubMed  Google Scholar 

  • Headache Classification Subcommittee of the international Headache Society: The International Headache Society (2004) The International Classification of Headache Disorders, 2nd edn. Cephalgia 24(Suppl 1):9–160

    Google Scholar 

  • Hoge CW, MCGurk D, Thomas JL et al (2008) Mild traumatic brain injury in US soldiers returning from Iraq. N Engl J Med 358:453–463

    Article  CAS  PubMed  Google Scholar 

  • Hoofien D, Gilboa A, Vakil E et al (2001) Traumatic brain injury (TBI) 10–20 years later: a comprehensive outcome study of psychiatric symptomatology, cognitive abilities and psychosocial functioning. Brain Inj 15:189–209

    Article  CAS  PubMed  Google Scholar 

  • Jennett B (1975) Epilepsy after non-missile head injuries. Year Book Medical Publishers Inc., Chicago, Print

    Google Scholar 

  • Jorge RE, Robinson RG, Arndt S (1993a) Are there symptoms that are specific for depressed mood in patients with traumatic brain injury? J Nerv Ment Dis 181:91–99

    Article  CAS  PubMed  Google Scholar 

  • Jorge RE, Robinson RG, Moser D et al (1993b) Depression following traumatic brain injury: a 1 year longitudinal study. J Affect Disord 27:233–243

    Article  CAS  PubMed  Google Scholar 

  • Joseph S, Masterson J (1999) Posttraumatic stress disorder and traumatic brain injury. J Trauma Stress 12:437–453

    Article  CAS  PubMed  Google Scholar 

  • King NS (1997) Post-traumatic stress disorder and head injury as a dual diagnosis: ‘islands’ of memory as a mechanism. J Neurol Neurosurg Psychiatry 62:82–84

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Klein P, Herr D, Pearl P et al (2012) Results of Phase 2 safety and feasibility study of treatment with levetiracetam for prevention of posttraumatic epilepsy. Arch Neurol 69(10):1290–1295

    Article  PubMed  PubMed Central  Google Scholar 

  • Kraus JF, Black MA, Hessol N et al (1984) The incidence of acute brain injury and serious impairment in a defined population. Am J Epidemiol 119(2):186–201

    CAS  PubMed  Google Scholar 

  • Krauss JK, Wakhloo AK, Nobbe F et al (1995) Lesion of dentatothalamic pathways in severe post-traumatic tremor. Neurol Res 17:409–416

    CAS  PubMed  Google Scholar 

  • Krauss JK, Trankle R, Kopp KH (1996) Post-traumatic movement disorders in survivors of severe head injury. Neurology 47(6):1488–1492

    Article  CAS  PubMed  Google Scholar 

  • Krauss JK, Trankle R, Raabe A (1997) Tremor and dystonia after penetrating diencephalic-mesencephalic trauma. Parkinsonism Relat Disord 3(2):117–119

    Article  CAS  PubMed  Google Scholar 

  • Levin H, Brown S, Song J et al (2001) Depression and posttraumatic stress disorder at three months after mild to moderate traumatic brain injury. J Clin Exp Neuropsychol 23(6):754–769

    Article  CAS  PubMed  Google Scholar 

  • Lucas S (2011) Headache management in concussion and mild traumatic brain injury. PM and R 3:S406–S412

    Article  PubMed  Google Scholar 

  • Lyons KE, Pahwa R (2008) Deep brain stimulation and tremor. Neurotherapeutics 5(2):331–338

    Article  PubMed  PubMed Central  Google Scholar 

  • Makley MJ, English JB, Drubach DA, Kreuz AJ et al (2008) Prevalence of sleep disturbance in closed head injury patients in a rehabilitation unit. Neurorehabil Neural Repair 2008:341–347

    Google Scholar 

  • Matthias JL, Alvaro PK (2012) Prevalence of sleep disturbances, disorders, and problems following traumatic brain injury: a meta-analysis. Sleep Med 12(7):898–905, Epub 15 Jun 2012

    Article  Google Scholar 

  • Mooney G, Speed J (2001) The association between mild traumatic brain injury and psychiatric concerns. Brain Inj 15:865–877

    Article  CAS  PubMed  Google Scholar 

  • Nampiaparampil D (2008) Prevalence of chronic pain after traumatic brain injury: a systematic review. JAMA 300(6):711–719

    Article  CAS  PubMed  Google Scholar 

  • Orff HJ, Ayalon L, Drummon SP (2009) Traumatic brain Injury and sleep disturbance: a review of current research. J Head Trauma Rehabil 24:155–165

    Article  PubMed  Google Scholar 

  • Otis J, McGlinchey R, Vasterling J et al (2011a) Complicating factors associated with mild traumatic brain injury: impact on pain and post-traumatic stress disorder treatment. J Clin Psychol Med Settings 18:145–154

    Article  PubMed  Google Scholar 

  • Otis J, McGlinchey R, Vasterling J (2011b) Complicating factors associated with mild traumatic brain injury: impact on pain and posttraumatic stress disorder treatment. J Clin Psychol Med Settings 18:145–154

    Article  PubMed  Google Scholar 

  • Ouellet MC, Beaulieu-Bonneau S, Morin CM (2006) Insomnia in patients with traumatic brain injury: frequency, characteristics, and risk factors. J Head Trauma Rehabil 21(3):199–212

    Article  PubMed  Google Scholar 

  • Padula W, Wu L, Vicci V et al (2007) Evaluating and treating visual dysfunction. In: Zasler ND, Katz DI, Zafonte RD (eds) Brain Injury medicine: principles and practice. Demos Medical Publishing, LLC., New York, pp 511–528

    Google Scholar 

  • Ponsford JI, Ziino C, Parcell DL, Shekleton JA et al (2012) Fatigue and sleep disturbance following traumatic brain injury—their nature, causes, and potential treatments. J Head Trauma Rehabil 27(3):224–233

    Article  PubMed  Google Scholar 

  • Ranjan N, Nair KP, Romanoski C, Singh R et al (2011) Tics after traumatic injury. Brain Inj 25(6):629–633

    Article  PubMed  Google Scholar 

  • Rao V, Spiro J, Vaishnavi S et al (2008) Prevalence and types of sleep disturbances acutely after traumatic brain injury. Brain Inj 22:381–386

    Article  PubMed  PubMed Central  Google Scholar 

  • Rapoport MJ, Chan F, Lanctot K et al (2009) An open-label study of citalopram for major depression in persons with traumatic brain injury. Arch Phys Med Rehabil 90(5):733–740

    Article  Google Scholar 

  • Rogers J, Read C (2007) Psychiatric comorbidity following traumatic brain injury. Brain Inj 21(13–14):1321–1333

    Article  PubMed  Google Scholar 

  • Schierhout G, Roberts I (1998) Prophylactic antiepileptic agents after head injury: a systematic review. J Neurol Neurosurg Psychiatry 64:108–112

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Seifert TD, Evans RW (2010) Posttraumatic headache: a review. Curr Pain Headache Rep 14:292–298

    Article  PubMed  Google Scholar 

  • Shumway-Cook A, Olmscheid R (1990) A systems analysis of postural dyscontrol in traumatically brain-injured patients. J Head Trauma Rehabil 5:51–62

    Article  Google Scholar 

  • Sojka P, Stalnacke B, Bjornstig U et al (2006) One-year follow-up of patients with mild traumatic brain injury: occurrence of post-traumatic stress-related symptoms at follow-up and serum levels of cortisol, S-100B and neuron specific enolase in acute phase. Brain Inj 20:613–620

    Article  PubMed  Google Scholar 

  • Temkin N (2009) Preventing and treating posttraumatic seizures: the human experience. Epilepsia 50(Suppl 2):10–13

    Article  PubMed  Google Scholar 

  • Temkin N, Dikmen S, Wilensky A et al (1990) A randomized, double blind study of phenytoin for the prevention of post-traumatic seizures. N Engl J Med 323:497–502

    Article  CAS  PubMed  Google Scholar 

  • Tham SW, Palermo TM, Vavilala MS et al (2012) The longitudinal course, risk factors, and impact of sleep disturbances in children with traumatic brain injury. J Neurotrauma 29:154–161

    Article  PubMed  PubMed Central  Google Scholar 

  • Thase ME (2008) Are SNRIs more effective than SSRIs? A review of the current state of the controversy. Psychopharmacol Bull 41:58–85

    PubMed  Google Scholar 

  • Trevena L. Cameron I, Porwal M (2004) Clinical practice guidelines for the care of people with traumatic brain injury in the community. Motor Accident Authority. Available at www.psych.usyd.edu.au/cemped/doc/Clinical_Prac_Guidelines_TBI_Full_report.pdf. Accessed 10 Dec 2012

  • Van Reekum R, Cohen T, Wong J (2000) Can traumatic brain injury cause psychiatric disorders? J Neuropsychiatry Clin Neurosci 12:316–327

    Article  PubMed  Google Scholar 

  • Yardley L, Beech S, Zander L, Evans T et al (1998) A randomized controlled trial of exercise therapy for dizziness and vertigo in primary care. Br J Gen Pract 48:1136–1140

    CAS  PubMed  PubMed Central  Google Scholar 

  • Zare M, Ahmadi K, Zadegan SA et al (2013) Effects of brain contusion on mild traumatic brain injured patients. Int J Neurosci 123(1):65–9. doi: 10.3109/00207454.2012.728653. Epub 2012 Oct 11. Erratum in: Int J Neurosci. 2013 Oct;123(10):744

    Google Scholar 

  • Zeitzer JM, Friedman L, O’Hara R (2009) Insomnia in the context of traumatic brain Injury. J Rehabil Res Dev 46:827–836

    Article  PubMed  Google Scholar 

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Tolleson, C. (2015). Traumatic Brain Injury, Neurological/Psychiatric Issues. In: Papadakos, P.J., Gestring, M.L. (eds) Encyclopedia of Trauma Care. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29613-0_653

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  • DOI: https://doi.org/10.1007/978-3-642-29613-0_653

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