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Biomonitoring

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Encyclopedia of Cancer
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Synonyms

Biological monitoring

Definition

Biological monitoring (i.e., biomonitoring) has conventionally been defined as “the periodic measurement of xenobiotic(s) or their metabolite(s) in accessible biological media for the comparison with an appropriate reference.” At present, a broader definition could be used that included effect biomarkers and biologically relevant dose, as well as biomarkers of susceptibility.

Characteristics

Biomonitoring is mainly aimed at:

  • Defining the existence of an occupational or environmental exposure

  • Quantifying the internal dose

  • Verifying that exposure limits are respected

The most commonly used matrices for biomonitoring are blood (and its components, e.g., serum and plasma) and urine.

Biological monitoring is complementary to the two other monitoring programs that are carried out to evaluate the health risk associated with exposure to pollutants, i.e., ambient monitoring and health surveillance. The basis of these monitoring programs is defined by...

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References

  • Bonassi S, Znaor A, Ceppi M et al (2007) An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis 28:625–631

    Article  CAS  PubMed  Google Scholar 

  • Hirvonen A (2005) Gene-environment interaction and biological monitoring of environmental exposures. Toxicol Appl Pharmacol 207:329–335

    Article  PubMed  Google Scholar 

  • Hirvonen A, Pelkonen O (2001) Measurement of drug metabolizing enzyme polymorphisms as indicators of susceptibility. In: Aitio A, Hayashi Y (eds) Biomarkers in risk assessment: validity and validation, Environmental health criteria, 222. World Health Organization, Geneva, pp 146–201

    Google Scholar 

  • National Research Council (NRC) (1987) Biological markers in environmental health research. Environ Health Perspect 74:3–9

    Google Scholar 

  • Shatzkin A, Freedman LS, Dorgan J (1997) Using and interpreting surrogate end-points in cancer research. In: Toniolo P, Boffetta P, Shuker DEG, Rothman N, Hulka B, Pearce N (eds) Application of biomarkers in cancer epidemiology. International Agency for Research on Cancer, Lyon, pp 265–271

    Google Scholar 

  • Van Damme K, Casteleyn L (2003) Current scientific, ethical and social issues of biomonitoring in the European Union. Toxicol Lett 144:117–126

    Article  PubMed  Google Scholar 

See Also

  • (2012) Adduct. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 43. doi:10.1007/978-3-642-16483-5_80

    Google Scholar 

  • (2012) Biomarkers. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 408–409. doi:10.1007/978-3-642-16483-5_6601

    Google Scholar 

  • (2012) Biotransformation. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 415. doi:10.1007/978-3-642-16483-5_651

    Google Scholar 

  • (2012) Cytogenetics. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 1050–1051. doi:10.1007/978-3-642-16483-5_1470

    Google Scholar 

  • (2012) Genotype. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1540. doi:10.1007/978-3-642-16483-5_2396

    Google Scholar 

  • (2012) Internal dose. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1897. doi:10.1007/978-3-642-16483-5_3105

    Google Scholar 

  • (2012) Kinetic parameters. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1943. doi:10.1007/978-3-642-16483-5_3223

    Google Scholar 

  • (2012) Metabolic capability. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2255. doi:10.1007/978-3-642-16483-5_3653

    Google Scholar 

  • (2012) Metabolite. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2258. doi:10.1007/978-3-642-16483-5_3661

    Google Scholar 

  • (2012) Phenotype. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2856. doi:10.1007/978-3-642-16483-5_4514

    Google Scholar 

  • (2012) Standardization. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3501. doi:10.1007/978-3-642-16483-5_5480

    Google Scholar 

  • (2012) Toxicology. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3734. doi:10.1007/978-3-642-16483-5_5873

    Google Scholar 

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Correspondence to Ari Hirvonen .

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Hirvonen, A. (2014). Biomonitoring. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_643-2

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  • DOI: https://doi.org/10.1007/978-3-642-27841-9_643-2

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  • Online ISBN: 978-3-642-27841-9

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