Definition
Kaplan–Meier survival analysis is a nonparametric method of summarizing survival event probabilities in tabular and graphical form.
Characteristics
Often, the focus of cancer epidemiology studies is on measurement of disease-free survival time (see also epidemiology of cancer). For example, the success of a breast cancer treatment might be discussed in terms of time-until-relapse or cancer-free survival time. To measure time effectively, a meaningful origin is chosen such as birth, first diagnosis of cancer, beginning of treatment, or last known occurrence of the disease. In a randomized study or clinical trial, we might begin measuring time at the point of randomization to treatment. Typically, time is measured prospectively in a survival study in contrast to the retrospective measurement of exposure in the case–control association study.
The outcome of interest is often measured as...
References
Allison PD (1995) Survival analysis using the SAS system: a practical guide. SAS Institute, Cary
Cox DR (1972) Regression models and life tables. J R Stat Soc B 34:187–220
Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457–481
Lee ET (1992) Statistical methods for survival data analysis, 2nd edn. Wiley, New York
See Also
(2012) Censoring. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 744. doi:10.1007/978-3-642-16483-5_1022
(2012) Cox Proportional Hazards Model. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 988–989. doi:10.1007/978-3-642-16483-5_1357
(2012) Mann–Whitney U-test. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2160. doi:10.1007/978-3-642-16483-5_3528
(2012) Nonparametric. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2538. doi:10.1007/978-3-642-16483-5_4122
(2012) Parametric. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2784. doi:10.1007/978-3-642-16483-5_4385
(2012) Randomization. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3164. doi:10.1007/978-3-642-16483-5_4944
(2012) Survival. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3583. doi:10.1007/978-3-642-16483-5_5606
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May, W.L. (2014). Kaplan-Meier Survival Analysis. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_3196-2
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DOI: https://doi.org/10.1007/978-3-642-27841-9_3196-2
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