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Pathomechanisms of Endogenously Aged Skin

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Textbook of Aging Skin

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Abstract

In an ever-aging society a better understanding of the underlying mechanisms accompanying aging skin has become essential. Skin aging can be classified into light-induced aging (photoaging, exogenous aging) and endogenous aging. The latter occurs in nonexposed areas, which are not in direct contact with environmental factors such as ultraviolet (UV) and infrared (IR) irradiation, and is mainly attributed to genetic factors and alterations of the endocrine environment. In this chapter, new insights on the latest findings regarding the pathogenesis of endogenously aged skin are summarized, to what extent intrinsic factors may influence the progress of skin aging and what are the consequences on the morphology and physiology of skin.

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Authors and Affiliations

  1. Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Auenweg 38, 06847, Dessau, Germany

    Evgenia Makrantonaki & Christos C. Zouboulis

  2. Geriatrics Research Group, Charité Universitätsmedizin Berlin, Berlin, Germany

    Evgenia Makrantonaki

  3. Department of Dermatology and Allergology, University Medical Center Ulm, Ulm, Germany

    Evgenia Makrantonaki

Authors
  1. Evgenia Makrantonaki
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  2. Christos C. Zouboulis
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Correspondence to Christos C. Zouboulis .

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Editors and Affiliations

  1. Procter & Gamble Co., Cincinnati, Ohio, USA

    Miranda A. Farage

  2. Procter & Gamble Co., Cincinnati, Ohio, USA

    Kenneth W. Miller

  3. Department Dermatology, University of California, San Francisco School of Medicine, San Francisco, California, USA

    Howard I. Maibach

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Makrantonaki, E., Zouboulis, C.C. (2015). Pathomechanisms of Endogenously Aged Skin. In: Farage, M., Miller, K., Maibach, H. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27814-3_9-2

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  • DOI: https://doi.org/10.1007/978-3-642-27814-3_9-2

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  • Online ISBN: 978-3-642-27814-3

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