Synonyms
Response: Improvement, either defined clinically or by rating scales (≥50% reduction in total score).
Remission: Absence of illness, either defined clinically or by rating scales (total score under a certain threshold).
Definition
Psychometrics: The measurement of psychological phenomena (symptoms).
Monitoring of Psychopharmacological Treatment in Depression
In the psychopharmacological treatment of depression, the common goal of the patient and the clinician is to relieve the severity of illness and, eventually, to achieve remission (i.e., absence of depression) (Papakostas and Fava 2010). Essentially, the monitoring of treatment effect can occur in two ways. Either the clinician simply assesses the patient over time by means of observation and general questions such as “Are you feeling better today?” or “Has your mood improved since your last visit?” This approach is simple, but perhaps insufficient in some cases since important information on symptoms may not be obtained....
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References
Bech P (2012) Clinical psychometrics. Wiley-Blackwell, Chichester
Hamilton M (1967) Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 6:278–296
Moller HJ (2001) Methodological aspects in the assessment of severity of depression by the Hamilton Depression Scale. Eur Arch Psychiatry Clin Neurosci 251:13–20
Montgomery SA, Asberg M (1979) A new depression scale designed to be sensitive to change. Br J Psychiatry 134:382–389
Newnham EA, Hooke GR, Page AC (2010) Monitoring treatment response and outcomes using the World Health Organization’s wellbeing index in psychiatric care. J Affect Disord 122:133–138
Papakostas G, Fava M (2010) Pharmacotherapy for depression and treatment-resistant depression. World Scientific, Singapore
Rush AJ, Fava M, Wisniewski SR, Lavori PW, Trivedi MH, Sackeim HA, Thase ME, Nierenberg AA, Quitkin FM, Kashner TM, Kupfer DJ, Rosenbaum JF, Alpert J, Stewart JW, McGrath PJ, Biggs MM, Shores-Wilson K, Lebowitz BD, Ritz L, Niederehe G, STAR*D Investigators Group (2004) Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design. Control Clin Trials 25:119–142
Rush AJ, Kraemer HC, Sackeim HA, Fava M, Trivedi MH, Frank E, Ninan PT, Thase ME, Gelenberg AJ, Kupfer DJ, Regier DA, Rosenbaum JF, Ray O, Schatzberg AF, Task Force ACNP (2006) Report by the ACNP Task Force on response and remission in major depressive disorder. Neuropsychopharmacology 31:1841–1853
Trivedi MH, Rush AJ, Wisniewski SR, Nierenberg AA, Warden D, Ritz L, Norquist G, Howland RH, Lebowitz B, McGrath PJ, Shores-Wilson K, Biggs MM, Balasubramani GK, Fava M, STAR*D Study Team (2006) Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice. Am J Psychiatry 163:28–40
World Health Organization (WHO) – Frederiksborg Psychiatric Research Unit, WHO Regional Office for Europe (1998) Mastering depression in primary care, version 2.2. Available via www.cure4you.dk at http://www.cure4you.dk/354/The_Depcare_Project.pdf. Assessed 29 Oct 2013
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Østergaard, S.D., Papakostas, G.I., Fava, M. (2013). Depression: Response and Remission. In: Stolerman, I., Price, L. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27772-6_7028-1
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DOI: https://doi.org/10.1007/978-3-642-27772-6_7028-1
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