Synonyms
Definition
Biosensors are analytical devices incorporating biological or biologically derived sensing elements with physicochemical transducers to produce digital electronic signals [1]. These biosensors determine the concentration of substances and other parameters of biological interest. The detecting elements of biosensors work in different physicochemical ways: optical, piezoelectric, electrochemical, thermometric, and magnetic. Biosensors using magnetics utilize the magnetic field created by magnetic particles that bind to target molecules in a biological assay (Fig. 1).
References
Turner APF, Karube I, Wilson GS (1987) Biosensors: fundamentals and applications. Oxford University Press, Oxford, p 770
Rife JC et al (2003) Design and performance of GMR sensors for the detection of magnetic microbeads in biosensors. Sens Actuator A 107:209–218
Graham DL, Ferreira HA, Freitas PP (2004) Magnetoresistive-based biosensors and biochip. Trends Biotechnol 22:455–462
Baselt DR, Lee GU, Natesan M, Metzger SW, Sheehan PE, Colton RJ (1998) A biosensor based on magnetoresistance technology. Biosens Bioelectron 13:731–739
Baselt DR, Lee GU, Natesan M, Hansen KM, Chrisey LA, Colton RJ (1995) A high-sensitive micromachined biosensor. Proc IEEE 85:672–680
Richardson J, Hill A, Luxton R, Hawkins P (2001) A novel measuring system for the determination of paramagnetic particle labels for use in magneto-immunoassays. Biosens Bioelectron 16:1127–1132
Lee S, Myers WR, Grossman HL, Cho HM, Chemla YR, Clarke J (2002) Magnetic gradiometer based on a high-transition temperature superconducting quantum interference device for improved sensitivity of a biosensor. Appl Phys Lett 81:3094–3096
Enpuku K, Hotta M, Nakahodo A (2001) High-Tc SQUID system for biological immunoassays. Physica C 357–360:1462–1465
Miller MM, Prinz GA, Cheng SF, Bounnak S (2002) Detection of a micron-sized magnetic sphere using a ring-shaped anisotropic magnetoresistance-based sensor: a model for a magnetoresistance-based biosensor. Appl Phys Lett 81:2211–2213
Besse PA, Boero G, Demierre M, Pott V, Potovic R (2002) Detection of a single magnetic microbead using a miniaturized silicon Hall sensor. Appl Phys Lett 80:4199–4201
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this entry
Cite this entry
Chon, C.H., Li, D. (2014). Biosensors Using Magnetics. In: Li, D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, Boston, MA. https://doi.org/10.1007/978-3-642-27758-0_101-2
Download citation
DOI: https://doi.org/10.1007/978-3-642-27758-0_101-2
Received:
Accepted:
Published:
Publisher Name: Springer, Boston, MA
Online ISBN: 978-3-642-27758-0
eBook Packages: Springer Reference EngineeringReference Module Computer Science and Engineering