Abstract
Due to forthcoming use of MPI on humans there is an urgent need for a thorough research on possible adverse effects of this technique on patients’ health. However, the health impact of exposure to time-varying magnetic fields in a frequency range between 10 kHz and 100 MHz, such as the MPI drive field, are still poorly investigated.
The current paper intends to give an overview on an in-silico approach to investigation of stimulating effects that could be caused by the MPI drive field. For this purpose, cell models of myocardiocyte, myocyte and neurocyte, as well as a suitable setup for the simulation of the exposure to time-varying magnetic fields have been developed. The evaluation of performed simulations was carried out on the basis of transmembrane voltage elevation and induced current densities.
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References
Gleich, B., Weizenecker, J.: Tomographic imaging using the nonlinear response of magnetic particles. Nature 435, 1214–1217 (2005)
Gabriel, S., Lau, R., Gabriel, C.: The dielectric properties of biological tissues: III. parametric models for the dielectric spectrum of tissues. Physics in Medicine and Biology 41, 2271–2293 (1996)
SEMCAD X, Version 14.6 Aletsch, http://www.semcad.com
ICNIRP: Guidelines for limiting exposure to time-varying electric, magnetic and electromagnetic fields (1 Hz to 100 kHz). Health Physics 99, 818–836 (2010)
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Kramlich, A., Bohnert, J., Dössel, O. (2012). Transmembrane Voltages Caused by Magnetic Fields – Numerical Study of Schematic Cell Models. In: Buzug, T., Borgert, J. (eds) Magnetic Particle Imaging. Springer Proceedings in Physics, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24133-8_54
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DOI: https://doi.org/10.1007/978-3-642-24133-8_54
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-24132-1
Online ISBN: 978-3-642-24133-8
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