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Transmembrane Voltages Caused by Magnetic Fields – Numerical Study of Schematic Cell Models

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Magnetic Particle Imaging

Part of the book series: Springer Proceedings in Physics ((SPPHY,volume 140))

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Abstract

Due to forthcoming use of MPI on humans there is an urgent need for a thorough research on possible adverse effects of this technique on patients’ health. However, the health impact of exposure to time-varying magnetic fields in a frequency range between 10 kHz and 100 MHz, such as the MPI drive field, are still poorly investigated.

The current paper intends to give an overview on an in-silico approach to investigation of stimulating effects that could be caused by the MPI drive field. For this purpose, cell models of myocardiocyte, myocyte and neurocyte, as well as a suitable setup for the simulation of the exposure to time-varying magnetic fields have been developed. The evaluation of performed simulations was carried out on the basis of transmembrane voltage elevation and induced current densities.

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References

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© 2012 Springer-Verlag GmbH Berlin Heidelberg

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Kramlich, A., Bohnert, J., Dössel, O. (2012). Transmembrane Voltages Caused by Magnetic Fields – Numerical Study of Schematic Cell Models. In: Buzug, T., Borgert, J. (eds) Magnetic Particle Imaging. Springer Proceedings in Physics, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24133-8_54

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