Abstract
Purpose: Dupuytren’s disease frequently results in crippling deformities of the hands and has a high incidence of recurrence after limited fasciectomy. We report a 36-year experience with full-thickness grafts to resurface defects created by releasing Dupuytren’s contractures with dermofasciectomies.
Methods: Dermofasciectomy and full-thickness skin grafts were used in 153 patients on 204 hands with Dupuytren’s contractures from 1970 to 2005.
Results: In the first part of the study, 36 hands in 24 patients were followed for an average of 3.9 years postoperatively between 1970 and 1985. There was no recurrent disease in the areas in the palms or digits covered by the full-thickness grafts. The incidence of extension outside the grafts was 8.3%. Were these results realistic and do they reflect the benefits of expanded grafts to reduce the incidence of recurrence and extension? To address that question, an additional cohort of patient was studied from 1985 to 2005. An additional 168 hands in 129 patients were treated with the same procedure and followed an average of 2.8 years postoperatively. Again, there was no recurrent disease in the areas of the palms or digits that had been covered by the grafts and the extension rate was comparable at 9.5%.
Conclusions: This study of 204 hands demonstrates the validity of using dermofasciectomy and full-thickness grafts in the treatment of patients with Dupuytren’s contracture who are likely to develop recurrent disease.
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References
Badalamente MA, Sterl L, Hurst LC (1983) The pathogenesis of Dupuytren’s contracture: contractile mechanisms of the myofibroblasts. J Hand Surg Am 8:235–242
Badalamente MA, Hurst LC, Hentz VR, Hotchkiss RN, Kaplan TD, Meals RA (2003) Collagen as a chemical target: nonoperative treatment of Dupuytren’s disease. J Hand Surg Am 27A:788–798
Berger P (1892) Traitment de la retraction de l’aponeurose palmaire par une autoplastie. Bull Acad Med 56:608
Fitzgerald AMP, Kirkpatrick JJR, Foo LTH, Naylor IL (1995) A picropolychrome staining technique applied to Dupuytren’s tissue. J Hand Surg Am 20B:519–524
Gonzalez R (1985) The use of skin grafts in the treatment of Dupuytren’s contracture. Hand Clin 1:641–647
Gordon SD (1963) Dupuytren’s contracture. The use of free skin grafts in treatment. In: Transactions of the 3 rd Congress of Plastic Surgery. Excerpta Medica Foundation, Amsterdam, pp 963–967
Hueston JT (1962) Digital Wolfe grafts in recurrent Dupuytren’s contracture. Plastic Reconstr Surg Transplant Bull 29:342–344
Hueston JT (1986) Dupuytren’s contracture. Lancet 2:1226
Hueston JT, Hurley JV, Whittingham S (1976) The contracting fibroblast as a clue to Dupuytren’s contracture. Hand 8:10–12
Ketchum LD, Donahue TK (2000) The injection of nodules of Dupuytren’s disease with triamcinolone Acetonide. J Hand Surg Am 25A:731–733
Ketchum L, Hixson P (1987) Dermofasciectomy and full-thickness grafts in the treatment of Dupuytren’s contracture. J Hand Surg Am 12A:659–663
Lexer E (1931) Die gesamte Wiederherstellungschirugie, vol 2, 2nd edn. JA Barth, Leipzig, p 837
McCann L, Belcher W, Warn A, Warn RM (1995) The presence of myofibroblasts in the dermis of patients with Dupuytren’s contracture. J Hand Surg Am 18B:656
McFarlane RM (1995) The current status of Dupuytren’s disease. J Hand Ther 8:181–184
Murrell GAC (1991) The role of the fibroblast, in Dupuytren’s contracture. Hand Clin 7:669–680
Piulachs P, Mir y Mir L (1952) Consideraciones sobre la enfermedad de Dupuytren. Folia Clin Int (Barcelona) 2:8
Rudolph R, Guber S, Suzuki M (1977) The life cycle of the myofibroblast. Surg Gynecol Obstet 145:399
Schneider LH, Hankin FM, Eisenberg T (1986) Surgery of Dupuytren’s disease: a review of the open palm method. J Hand Surg Am 11A:23–27
Tomasek JJ, Vaughn MB, Haaksma CJ (1999) Cellular structure and biology of Dupuytren’s disease. Hand Clin 15:21–34
Tonkin MA, Burke FD, Varian JPW (1984) Dupuytren’s contracture: a comparative study of fasciectomy and dermofasciectomy in one hundred patients. J Hand Surg Am 9B:156–162
Tubiana R (1985) Recurrent Dupuytren’s disease. In: Hueston JT, Tubiana R (eds) Dupuytren’s disease, 2nd edn. Churchill Livingstone, Edinburgh
Vracko R (1974) Basal lamina layering in diabetes mellitus: evidence for accelerated rate of cell death and cell regeneration. Diabetes 23:94–104
Watt AJ, Curtin CM, Hentz VR (2010) Collagen injection as nonoperative treatment of Dupuytren’s disease: 8 year follow-up. J Hand Surg Am 35A:534–539
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The author would like to thank Mrs. DeLois McPherson for her invaluable help in preparing this manuscript.
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Ketchum, L.D. (2012). Expanded Dermofasciectomies and Full-Thickness Grafts in the Treatment of Dupuytren’s Contracture: A 36-Year Experience. In: Eaton, C., Seegenschmiedt, M., Bayat, A., Gabbiani, G., Werker, P., Wach, W. (eds) Dupuytren’s Disease and Related Hyperproliferative Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22697-7_26
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