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Molecular Lipophilicity: A Predominant Descriptor for QSAR

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Chemogenomics and Chemical Genetics

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Abstract

The discovery of a new medicine is a complex and costly process, in which the role of chance and fortuitous observation is often predominant. Substantial effort has been afforded to rationalise the discovery process as much as possible. The methodologies relevant to rational drug design (according to international terminology) are today omnipresent as much in academic research centres as in industry.

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Author information

Authors and Affiliations

  1. Centre for Structural Biochemistry, Faculty of Pharmacy, CNRS - Servier - University of Montpellier - INSERM, Montpellier, France

    Gérard Grassy (Professor at the University of Montpellier, Correspondent of the National Academy of Pharmacy, Professeur Agrégé in Pharmacy) & Alain Chavanieu (Lecturer at Montpellier University)

Authors
  1. Gérard Grassy
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  2. Alain Chavanieu
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Editor information

Editors and Affiliations

  1. UMR 5168 CNRS CEA INRA UNIV JF, Joseph Fourier University, Rue des Martyrs 17, 38054 Grenoble Cedex 9, France

    ERIC MARECHAL

  2. Institute of Life Sciences Research and, Lab. of Plant Cell Physiology, CNRS-CEA-INRA, Joseph Fourier University, Grenoble, France

    Sylvaine Roy

  3. Department of Cellular Differentiation a, Albert Bonniot Institute, Rond-point de la Chantourne, La Tronche Cedex, 38706, France

    Laurence Lafanechère

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Grassy, G., Chavanieu, A. (2011). Molecular Lipophilicity: A Predominant Descriptor for QSAR. In: MARECHAL, E., Roy, S., Lafanechère, L. (eds) Chemogenomics and Chemical Genetics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19615-7_12

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