Skip to main content
SpringerLink
Log in

Peptic Ulcer Disease

  • Reference work entry
Book cover Abdominal Imaging

  • 539 Accesses

Abstract

Despite major advances in medicine, peptic ulceration remains a major problem. More than 10% of the adult population will suffer from a gastric or duodenal ulcer (Lu et al. 2004). Most will suffer symptoms such as pain; many will suffer complications occasionally leading to mortality (Westbrook et al. 2001). Improvements in diagnostic techniques have allowed more precise determination of the underlying etiology. However, some gastric ulcers remain associated with malignancy requiring that these lesions are carefully evaluated and followed up to differentiate benign from malignant.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 1,099.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 1,599.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Arista S, Sailler L, Astudillo L. Relapsing esophageal and gastric ulcers revealing Wegener’s granulomatosis. Am J Med. 2005;118:923.

    Article  PubMed  Google Scholar 

  • Bytzer P, Teglbjaerg PS, Danish Ulcer Study Group. Helicobacter pylori-negative duodenal ulcers: prevalence, clinical characteristics, and prognosis – results from a randomized trial with 2-year follow-up. Am J Gastroenterol. 2001;96:1409.

    PubMed  CAS  Google Scholar 

  • Cappell MS, Taunk JL. A chronic gastric ulcer refractory to conventional antiulcer therapy associated with localized gastric Mycobacterium avium intracellulare infection. Am J Gastroenterol. 1991;86:654.

    PubMed  CAS  Google Scholar 

  • Ciociola AA, McSorley DJ, Turner K, et al. Helicobacter pylori infection rates in duodenal ulcer patients in the United States may be lower than previously estimated. Am J Gastroenterol. 1999;94:1834.

    Article  PubMed  CAS  Google Scholar 

  • Collen MJ, Santoro MJ, Chen YK. Giant duodenal ulcer. Evaluation of basal acid output, nonsteroidal antiinflammatory drug use, and ulcer complications. Dig Dis Sci. 1994;39:1113.

    Article  PubMed  CAS  Google Scholar 

  • Cooke L, Hutton CF. Postbulbar duodenal ulceration. Lancet. 1958;1:757.

    Google Scholar 

  • Dees A, Batenburg PL, Umar HM, et al. Strongyloides stercoralis associated with a bleeding gastric ulcer. Gut. 1990;31:1414.

    Article  PubMed  CAS  Google Scholar 

  • Elashoff JD, Van Deventer G, Reedy T, et al. Long-term follow-up of duodenal ulcer patients. J Clin Gastroenterol. 1983;5:509.

    Article  PubMed  CAS  Google Scholar 

  • El-Omar E, Penman I, Dorrian CA, et al. Eradicating Helicobacter pylori infection lowers gastrin mediated acid secretion by two thirds in patients with duodenal ulcer. Gut. 1993;34:1060.

    Article  PubMed  CAS  Google Scholar 

  • El-Omar EM, Penman ID, Ardill JE, et al. Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology. 1995;109:681.

    Article  PubMed  CAS  Google Scholar 

  • Farman J, Ramirez G, Rybak B, et al. Gastric sarcoidosis. Abdom Imaging. 1997;22:248.

    Article  PubMed  CAS  Google Scholar 

  • Grassi R, Romano S, Pinto A, Romano L. Gastro-duodenal perforations: conventional plain film, US and CT findings in 166 consecutive patients. Eur J Radiol. 2004;50(1):30–36.

    Article  PubMed  Google Scholar 

  • Gulmez SE, Lassen AT, Aalykke C, et al. Spironolactone use and the risk of upper gastrointestinal bleeding: a population-based case–control study. Br J Clin Pharmacol. 2008;66:294.

    Article  PubMed  CAS  Google Scholar 

  • Hallas J, Dall M, Andries A, et al. Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: population based case–control study. Br Med J. 2006;333:726.

    Article  Google Scholar 

  • Hilton D, Iman N, Burke GJ, et al. Absence of abdominal pain in older persons with endoscopic ulcers: a prospective study. Am J Gastroenterol. 2001;96:380.

    Article  PubMed  CAS  Google Scholar 

  • Hogan DL, Rapier RC, Dreilinger A, et al. Duodenal bicarbonate secretion: eradication of Helicobacter pylori and duodenal structure and functions in humans. Gastroenterology. 1996;110:705.

    Article  PubMed  CAS  Google Scholar 

  • Huang JQ, Sridhar S, Hunt RH. Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis. Lancet. 2002;359:14.

    Article  PubMed  CAS  Google Scholar 

  • Isenberg J, McQuaid K, Laine L, Walsh J. Acid-peptic disorders. In: Yamada T, editor. Textbook of gastroenterology. 2nd ed. Philadelphia: JP Lippincott; 1995. p. 1347.

    Google Scholar 

  • Konturek PC, Ernst H, Konturek SJ, et al. Mucosal expression and luminal release of epidermal and transforming growth factors in patients with duodenal ulcer before and after eradication of Helicobacter pylori. Gut. 1997;40:463.

    PubMed  CAS  Google Scholar 

  • Levine MS. Peptic ulcers. In: Gore RM, Levine MS, editors. Textbook of gastrointestinal radiology. 2nd ed. Philadelphia: WB Saunders; 2000. p. 514–545.

    Google Scholar 

  • Low VHS, Heyneman LH. Gastric ulceration due to sarcoidosis. Am J Roentgenol. 1999;172:251.

    Article  CAS  Google Scholar 

  • Low VHS, Heyneman LH, Hough D. Inflammatory pseudotumor of the postbulbar duodenum. Australas Radiol. 1998;42:370–373.

    Article  PubMed  CAS  Google Scholar 

  • Lu CL, Chang SS, Wang SS, et al. Silent peptic ulcer disease: frequency, factors leading to “silence,” and implications regarding the pathogenesis of visceral symptoms. Gastrointest Endosc. 2004;60:34.

    Article  PubMed  Google Scholar 

  • McColl KE, el-Nujimi AM, Chittajallu RS, et al. A study of the pathogenesis of Helicobacter pylori negative chronic duodenal ulceration. Gut. 1993;34:762.

    Article  PubMed  CAS  Google Scholar 

  • Miyake K, Kusunoki M, Shinji Y, et al. Bisphosphonate increases risk of gastroduodenal ulcer in rheumatoid arthritis patients on long-term nonsteroidal antiinflammatory drug therapy. J Gastroenterol. 2009;44:113.

    Article  PubMed  CAS  Google Scholar 

  • Newton EB, Versland MR, Sepe TE. Giant duodenal ulcers. World J Gastroenterol. 2008;14(32):4995–4999.

    Article  PubMed  Google Scholar 

  • Peura DA. Ulcerogenesis: integrating the roles of Helicobacter pylori and acid secretion in duodenal ulcers. Am J Gastroenterol. 1997;92:8S.

    PubMed  CAS  Google Scholar 

  • Rahme E, Barkun A, Nedjar H, et al. Hospitalizations for upper and lower GI events associated with traditional NSAIDs and acetaminophen among the elderly in Quebec, Canada. Am J Gastroenterol. 2008;103:872.

    Article  PubMed  CAS  Google Scholar 

  • Regan F, Tran T. Duodenal tuberculosis – a continuing diagnostic challenge (letter). Postgrad Med J. 1990;66:787.

    Article  PubMed  CAS  Google Scholar 

  • Tromba JL, Inglese R, Rieders B, et al. Primary gastric tuberculosis presenting as pyloric outlet obstruction. Am J Gastroenterol. 1991;86:1820.

    PubMed  CAS  Google Scholar 

  • Tytgat G, Langenberg W, Rauws E, Rietra P. Campylobacter-like organism (CLO) in the human stomach. Gastroenterology. 1985;88:1620.

    Google Scholar 

  • Weissman D, Gumaste VV, Dave PB, Keh W. Bleeding from a tuberculous gastric ulcer. Am J Gastroenterol. 1990;85:742.

    PubMed  CAS  Google Scholar 

  • Westbrook JI, McIntosh JH, Duggan JM. Accuracy of provisional diagnoses of dyspepsia in patients undergoing first endoscopy. Gastrointest Endosc. 2001;53:283.

    PubMed  CAS  Google Scholar 

  • Wyatt JI, Rathbone BJ, Dixon MF, et al. Campylobacter pyloridis and acid induced gastric metaplasia in the pathogenesis of duodenitis. J Clin Pathol. 1987;40:841.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medicine, University of Western Australia, 6009, Crawley, WA, Australia

    Vincent H. S. Low MBBS, FRANZCR (Associate Professor)

Authors
  1. Vincent H. S. Low MBBS, FRANZCR
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vincent H. S. Low MBBS, FRANZCR .

Editor information

Editors and Affiliations

  1. Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany

    Bernd Hamm

  2. Department of Radiology, Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA

    Pablo R. Ros

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Low, V.H.S. (2013). Peptic Ulcer Disease. In: Hamm, B., Ros, P.R. (eds) Abdominal Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-13327-5_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-13327-5_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-13326-8

  • Online ISBN: 978-3-642-13327-5

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation