Abstract
The purpose of this book chapter is to provide a basic introduction to the field of magnetic resonance imaging (MRI) and its extension to small animal imaging using magnetic resonance microscopy (MRM). The chapter starts with a section describing the most fundamental aspects of MR including the resonance phenomena, relaxation mechanisms, and the basic physical processes leading to MR signal generation. Afterwards the concept of magnetic field gradients leading to the most basic imaging principles of MRI and MRM will be summarized. This introduction will be completed by giving an overview over the MR hardware involved, the basic information content of a MRM experiment and finally challenges and limitations of this imaging technology and some imaging examples will be discussed.
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Acknowledgment
This work was supported by the Deutsche Forschungsgemeinschaft with grants Ad 132/3-1, Ba 1433/4-1, Fl 225/2-1 and Mu 576/14-1 and the Graduiertenkolleg 1048 “Organogenesis.” The author would like to thank Esra Lang, Gerd Melkus, Philipp Mörchel, Simon Triphan for contributing to Figs. 12.5 and 12.6.
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© 2011 Springer-Verlag Berlin Heidelberg
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Jakob, P. (2011). Small Animal Magnetic Resonance Imaging: Basic Principles, Instrumentation and Practical Issue. In: Kiessling, F., Pichler, B. (eds) Small Animal Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12945-2_12
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DOI: https://doi.org/10.1007/978-3-642-12945-2_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-12944-5
Online ISBN: 978-3-642-12945-2
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