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Kidney Functions in Untreated and IGF-I Treated Patients with Laron Syndrome

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Laron Syndrome - From Man to Mouse

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Renal functions were studied in children and adults with Laron syndrome in the untreated and IGF-I treated state.

In untreated patients the glomerular filtration rate is below normal and rises during IGF-I treatment as does blood urea nitrogen and serum phosphorus. In the initial phase of treatment there is transitory water retention and hypercalciuria.

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Acknowledgment

We acknowledge the assistance of Amir Yahav in the preparation of Figs. 34.6–34.14, which were performed in partial fulfillment of the MD thesis requirements of the Sackler Faculty of Medicine, Tel Aviv University

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Authors and Affiliations

  1. Research Unit, Schneider Children’s Medical Center of Israel, Kaplan Street 14, 49202, Petah Tikva, Israel

    Zvi Laron

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  1. Zvi Laron
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Correspondence to Zvi Laron .

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Editors and Affiliations

  1. Endocrinology & Diabetes Research Unit, Schneider Children's Hospital, Kaplan Street 14, Petah Tikva, 49 202, Israel

    Zvi Laron

  2. Edison Biotechnology Institute, Ohio University, Athens, 45701, Ohio, USA

    J. Kopchick

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Laron, Z. (2011). Kidney Functions in Untreated and IGF-I Treated Patients with Laron Syndrome. In: Laron, Z., Kopchick, J. (eds) Laron Syndrome - From Man to Mouse. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11183-9_34

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  • DOI: https://doi.org/10.1007/978-3-642-11183-9_34

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-11182-2

  • Online ISBN: 978-3-642-11183-9

  • eBook Packages: MedicineMedicine (R0)

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