Abstract
β-thalassemia major is a hereditary hemolytic anemia, characterized by deficiency in the hemoglobin beta chain synthesis. Patients with β-thalassemia major are prone to repeated attacks of intravascular hemolysis that requires repeated hospitalization and blood transfusions.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
For Further Reading
Papakonstantinou O et al MR imaging of spleen in beta-thalassemia major. Abdom Imaging. 2006. doi: 10.1007/ s00261.006.9138–4
Lal A et al Focal splenic lesions as a cause of extramedul-lary hematopoiesis in a case of thalassemia. Eur J Radiol Extra. 2008;68:e125–7
Karimi M et al Hypoparathyroidism and intracerebral cal-cification in patients with beta-thalassemia major. Eur J Radiol. 2008. doi: 10.1016/j.ejrad.2008.02.003
Drakonaski E et al Adrenal glands in beta-thalassemia major: magnetic resonance (MR) imaging features and correlation with iron store. Eur Radiol. 2005;15:2462–68
Louis CK Low growth of children with b-thalassemia major. Indian J Pediatr. 2005;72:159–64
Mavrogeni S et al Magnetic resonance evaluation of liver and myocardium iron deposition in thalassemia intermedia and βthalassemia major. Int J Cardiovasc Imaging 2008;24:849–54
Karimi M et al Prevalence of hepatosplenomegaly in beta thalassemia minor subjects in Iran. Eur J Radiol. 2007. doi: 10.1016/j.ejrad.2007.09.027
Argyropoulou MI et al MRI evaluation of tissue iron burden in patients with βthalassemia major. Pediatr Radiol. 2007;37:1191–200
Positano V et al Improved T2* assessment in liver iron overload by magnetic resonance imaging. Magn Reson Imaging. 2008. doi:10.1016/j.mri.2008.06.004
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Al-Tubaikh, J.A. (2010). β-Thalassemia Major (Cooley's Anemia). In: Al-Tubaikh, J.A. (eds) Internal Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03709-2_56
Download citation
DOI: https://doi.org/10.1007/978-3-642-03709-2_56
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-03708-5
Online ISBN: 978-3-642-03709-2
eBook Packages: MedicineMedicine (R0)