Abstract
Liver cirrhosis is a term used to describe the histologi-cal development of regenerative hepatic nodules surrounded by fibrous bands in response to chronic liver injury.
Cirrhosis is an advanced, diffuse stage of liver injury, which is characterized by replacement of the normal liver parenchyma by collagenous scar (fibrosis). Cirrhosis is accompanied by diffuse distortion of the hepatic vasculature and architecture, resulting in vascular disturbance between the portal veins and the hepatic veins, plus porta hepatic fibrosis. The major cirrhosis consequences are hepatic function impairment, increased intrahepatic resistance (portal hypertension), and the development of hepatocellular carcinoma (HCC).
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Schuppan D et al Liver cirrhosis. Lancet. 2008;371:838–51
Colli A et al Severe liver fibrosis or cirrhosis: accuracy of US for detection—analysis of 300 cases. Radiology. 2003; 227:89–94
Ito K et al Imaging findings of unusual intra- and extrahe-patic portosystemic collaterals. Clin Radiol. 2009;64:200–07
Meyer CA et al Diseases of the hepatopulmonary axis. RadioGraphics. 2000;20:687–98
Lim JH et al Regenerative nodules in liver cirrhosis: find- ings at CT during arterial portography and CT arteriogra-phy with histopathologic correlation. Radiology. 1999;210:451–58
Martinez-Noguera A et al Doppler in hepatic cirrhosis and chronic hepatitis. Semin Ultrasound CT MR. 2002;23:19–36
Palazzi C et al Hepatitis C virus-related arthritis. Autoimmun Rev 2008;8:48–51
Bonekamp S et al Can imaging modalities diagnose and stage hepatic fibrosis and cirrhosis accurately. J Hepatol. 2009;50:17–35
Chavhan GB et al Normal Doppler spectral-waves of major pediatric vessels: specific patterns. RadioGraphics 2008;28:691–706
Ba-Ssalamah A et al Dedicated multi-detector CT of the esophagus: spectrum of diseases. Abdom Imaging. 2009;34:3–18
Verma SK et al Dilated cisternae chyli: a sign of uncompen- sated cirrhosis at MR imaging. Abdom Imaging. 2009;34:211–16
Sharma S et al MRI diagnosis of plantar fibromatosis—a rare anatomic location. The Foot. 2003;13:219–22
Mauro MA et al Computed tomography of hepatic venous hypertension: the reticulated-mosaic pattern. Gastrointest Radiol. 1990;15:35–38
Kobayashi S et al MRI findings of primary biliary cirrhosis: correlation with Scheuer histologic staging. Abdom Imaging. 2005;30:71–76
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Al-Tubaikh, J.A. (2010). Liver Cirrhosis. In: Al-Tubaikh, J.A. (eds) Internal Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03709-2_1
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DOI: https://doi.org/10.1007/978-3-642-03709-2_1
Publisher Name: Springer, Berlin, Heidelberg
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