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Sexually Transmitted Diseases

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Textbook of Clinical Pediatrics

Definition/Classification

Sexually transmitted diseases (STD) are infections caused by a varied group of organisms, including bacteria (Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum), viruses (herpes simplex virus, HIV, human papilloma virus), and parasites (Trichomonas vaginalis) that are transmitted predominantly by sexual activity. STDs can also occur in young children, which can have serious social and medical legal implications. Children can acquire an STD during delivery from their mothers, if they happen to be infected, from sexual abuse or from consensual sexual activity as adolescents. Identification of an STD in a young child can initiate an investigation of sexual abuse. However, the diagnosis or how the infection was acquired may not be certain.

The Committee on Child Abuse and Neglect of the American Academy of Pediatrics defines child sexual abuse as “… when a child is engaged in sexual activities that he or she cannot comprehend, for which the child is...

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References

  • Adu-Sarkodie Y, Opuku BK, Crucitti T et al (2007) Lack of evidence for the involvement of rectal and oral trichomonads in the aetiology of vaginal trichomoniasis in Ghana. Sex Transm Dis 83:130–132

    CAS  Google Scholar 

  • Bauwens JE, Gibbons MS, Hubbard MM (1991) Chlamydia pneumoniae (strain TWAR) isolated from two symptom-free children during evaluation for possible sexual assault. J Pediatr 119:591–593

    Article  PubMed  CAS  Google Scholar 

  • Black CM, Driebe EM, Howard LA et al (2009) Multicenter study of nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in children being evaluated for sexual abuse. Pediatr Infect Dis J 28:608–613

    Article  PubMed  Google Scholar 

  • Briselden AM, Hillier SL (1994) Evaluation of affirm VP microbial identification test for Gardnerella vaginalis and Trichomonas vaginalis. J Clin Microbiol 32:148–152

    PubMed  CAS  Google Scholar 

  • Campbell L, Woods V, Lloyd T et al (2008) Evaluation of the OSOM Trichomonas rapid test versus wet preparation examination for detection of Trichomonas vaginalis vaginitis in specimens from women with a low prevalence of infection. J Clin Microbiol 46:3467–3469

    Article  PubMed  CAS  Google Scholar 

  • Centers for Disease Control and Prevention (1991) False-positive results with the use of chlamydia tests in the evaluation of suspected sexual abuse-Ohio, 1990. Morb Mortal Wkly Rep 39:932–935

    Google Scholar 

  • Centers for Disease Control and Prevention (2006) Discontinuation of spectinomycin. Morb Mortal Wkly Rep 55:370

    Google Scholar 

  • Centers for Disease Control and Prevention (2008) Syphilis testing algorithms using treponemal tests for initial screening. Four laboratories, New York city, 2005–2006. Morb Mortal Wkly Rep 57:872–875

    Google Scholar 

  • Centers for Disease Control and Prevention (2010) Sexually transmitted diseases guidelines 2010. Morb Mortal Wkly Rep 59(RR-12):1–116

    Google Scholar 

  • Christian CW, Lavelle J, Bell LM (1999) Preschoolers with syphilis. Pediatrics 103:1–5. http://www.pediatrics.org/cgi/content/full/103/1/e4

    Google Scholar 

  • Corey L, Wald A (2009) Maternal and neonatal herpes simplex virus infections. N Engl J Med 361:1376–1385

    Article  PubMed  CAS  Google Scholar 

  • De Villiers FPR, Prentice MA, Bergh AM (1992) Sexually transmitted disease surveillance in a child abuse clinic. S Afr Med J 81:84–86

    PubMed  Google Scholar 

  • Galarza PG, Abad R, Canigia LF et al (2010) New mutation in 23S rRNA gene associated with high levels of azithromycin resistance in Neisseria gonorrhoeae. Antimicrob Agents Chemother 54:1652–1653

    Article  PubMed  CAS  Google Scholar 

  • Garber GF (2005) The laboratory diagnosis of Trichomonas vaginalis. Can J Infect Dis Med Microbiol 16:35–38

    PubMed  Google Scholar 

  • Giradet RG, Lahoti S, Howard LA et al (2009) The epidemiology of sexually transmitted infections in suspected child victims of sexual assault. Pediatrics 124:79–86

    Article  Google Scholar 

  • Goldenring JM (1989) Secondary syphilis in a prepubertal child. Differentiating condyloma lata from condyloma acuminata. NY State J Med 89:180–181

    CAS  Google Scholar 

  • Hammerschlag MR, Guillen CD (2010) Medical and legal implications of testing for sexually transmitted infections in children. Clin Microbiol Rev 23:493–506

    Article  PubMed  CAS  Google Scholar 

  • Hammerschlag MR, Rettig PJ, Shields ME (1988) False positive results with the use of chlamydial antigen detection tests in the evaluation of suspected sexual abuse in children. Pediatr Infect Dis J 7:11–14

    Article  PubMed  CAS  Google Scholar 

  • Ingram DL, Everett VD, Lyna PR et al (1992) Epidemiology of adult sexually transmitted disease agents in children being evaluated for sexual abuse. Pediatr Infect Dis J 11:945–50

    Article  PubMed  CAS  Google Scholar 

  • Ison C, Bellinger CM, Walker J (1986) Homology of cryptic plasmid of Neisseria gonorrhoeae with plasmids from Neisseria meningitidis and Neisseria lactamica. J Clin Pathol 39:1119–1123

    Article  PubMed  CAS  Google Scholar 

  • Katz AR, Effler PV, Ohye RG et al (2004) False-positive gonorrhea test results with a nucleic acid amplification test: the impact of low prevalence on positive predictive value. Clin Infect Dis 38:814–819

    Article  PubMed  Google Scholar 

  • Kellogg N (2005) The evaluation of sexual abuse in children. Pediatrics 116:506–512

    Article  PubMed  Google Scholar 

  • Kelly P, Koh J (2006) Sexually transmitted infections in alleged sexual abuse of children and adolescents. J Paediatr Child Health 42:434–440

    Article  PubMed  Google Scholar 

  • Kohlberger P, Bancher-Todesca D (2007) Bacterial colonization in suspected sexually abused children. J Pediatr Adolesc Gynecol 20:289–292

    Article  PubMed  Google Scholar 

  • Kumar S, Kumar S, Kohlhoff SA (2006) Recurrent HSV-2 meningitis in a 9-year-old girl. Scand J Infect Dis 38:570–572

    Article  PubMed  Google Scholar 

  • Leach CT, Ashley RL, Baillargeon J et al (2002) Performance of two commercial glycoprotein-G-based enzyme immunoassays for detecting antibodies to herpes simplex viruses 1 and 2 in children and young adolescents. Clin Diagn Lab Immunol 9:1124–1125

    PubMed  CAS  Google Scholar 

  • Myhre AK, Dalen A, Berntzen K et al (2003) Anogenital papillomavirus in non-abused children. Acta Pediatr 92:1445–1452

    Article  CAS  Google Scholar 

  • Nye MB, Schwebke JR, Body BA (2009) Comparison of APTIMA Trichomonas vaginalis transcription-mediated amplification to wet mount microscopy, culture, and polymerase chain reaction for diagnosis of trichomoniasis in men and women. Am J Obstet Gynecol 200:188.e1–188.e7

    Article  Google Scholar 

  • Palmer HM, Mallinson H, Wood RL et al (2003) Evaluation of the specificities of five DNA amplification methods for the detection of Neisseria gonorrhoeae. J Clin Micobiol 41:835–837

    Article  CAS  Google Scholar 

  • Porder K, Sanchez N, Roblin PM et al (1989) Lack of specificity of chlamydiazyme for detection of vaginal chlamydial infection in prepubertal girls. Pediatr Infect Dis J 8:358–360

    Article  PubMed  CAS  Google Scholar 

  • Public Health Agency of Canada (2010) Canadian guidelines on sexually transmitted infections. www.publichealth.gc.ca/sti

  • Ramos S, Lukefahr JL, Morrow RA et al (2006) Prevalence of herpes simplex virus types 1 and 2 among children and adolescents attending a sexual abuse clinic. Pediatr Infect Dis J 25:902–905

    Article  PubMed  Google Scholar 

  • Reading R, Rannan-Eliya Y (2007) Evidence for sexual transmission of genital herpes in children. Arch Dis Child 92:608–613

    Article  PubMed  Google Scholar 

  • Robinson AJ, Watkeys JEM, Ridgway GL (1998) Sexually transmitted organisms in sexually abused children. Arch Dis Child 79:356–358

    Article  PubMed  CAS  Google Scholar 

  • Siegfried E, Rasnick-Conley J, Cook S et al (1998) Human papillomavirus screening in pediatric victims of sexual abuse. Pediatrics 101:43–47

    Article  PubMed  CAS  Google Scholar 

  • Simmons KJ, Hicks DJ (2005) Child sexual abuse examination: is there a need for routine screening for N. gonorrhoeae and C. trachomatis. J Pediatr Adolesc Gynecol 18:343–345

    Article  PubMed  Google Scholar 

  • Sinclair KA, Woods CR, Kirse DJ et al (2005) Anogenital and respiratory tract human papillomavirus infections among children: age, gender and potential transmission through sexual abuse. Pediatrics 116:815–825

    Article  PubMed  Google Scholar 

  • Stevens-Simon C, Nelligan D, Breese P et al (2000) The prevalence of genital human papillomavirus infections in abused and nonabused preadolescent girls. Pediatrics 106:645–649

    Article  PubMed  CAS  Google Scholar 

  • Tabrizi SN (2010) Quality assessment for human papillomavirus testing. Sex Health 7:335–337

    Article  PubMed  Google Scholar 

  • Tabrizi SN, Chen S, Cohenford MA et al (2004) Evaluation of real time polymerase chain reaction assays for confirmation of Neisseria gonorrhoeae in clinical samples tested positive in the Roche Cobas Amplicor assay. Sex Transm Infect 80:68–71

    Article  PubMed  CAS  Google Scholar 

  • Tsang RS, Martin IE, Lau A et al (2007) Serological diagnosis of syphilis: comparison of the Trep-Check IgG enzyme immunoassay with other screening and confirmatory tests. FEMS Immunol Med Microbiol 51:118–124

    Article  PubMed  CAS  Google Scholar 

  • Unger ER, Fajman NN, Maloney EM et al (2011) Anogenital human papillomavirus in sexually-abused and nonabused children: results of a multicenter study. Pediatrics (in press)

    Google Scholar 

  • Whiley DM, Tapsall JW, Sloots TP (2006) Nucleic acid amplification testing for Neisseria gonorrhoeae. An ongoing challenge. J Mol Diagn 8:3–14

    Article  PubMed  CAS  Google Scholar 

  • Whittington WL, Rice RJ, Biddle JW et al (1988) Incorrect identification of Neisseria gonorrhoeae from infants and children. Pediatr Infect Dis J 7:3–10

    Article  PubMed  CAS  Google Scholar 

  • Woods CR (2005) Syphilis in children: congenital and acquired. Semin Pediatr Infect Dis 16:245–257

    Article  PubMed  Google Scholar 

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Correspondence to Margaret R. Hammerschlag M.D. .

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Hammerschlag, M.R. (2012). Sexually Transmitted Diseases. In: Elzouki, A.Y., Harfi, H.A., Nazer, H.M., Stapleton, F.B., Oh, W., Whitley, R.J. (eds) Textbook of Clinical Pediatrics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02202-9_71

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  • DOI: https://doi.org/10.1007/978-3-642-02202-9_71

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-02201-2

  • Online ISBN: 978-3-642-02202-9

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