Introduction
Extracorporeal membrane oxygenation (ECMO) is an effective, but costly and invasive rescue therapy for term and late preterm infants with reversible heart and/or lung failure unresponsive to maximal conventional therapies. These include less invasive newer technologies, such as, high-frequency ventilation, surfactant replacement therapy, and inhaled nitric oxide (iNO). ECMO is the application of modified extracorporeal bypass technology for a period of days to weeks to provide temporary life support allowing the injured lungs and/or heart to recover. The first successful clinical application in infants was reported by Bartlett in 1976 and the treatment began to be adopted widely in the mid to late 1980s. ECMO has been shown to significantly improve mortality in a randomized controlled trial and has been the standard of care in industrialized countries for over 20 years. Availability in less-developed countries is limited due to its high expense, need for sophisticated...
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Keszler, M. (2012). ECMO (Extracorporeal Membrane Oxygenation). In: Elzouki, A.Y., Harfi, H.A., Nazer, H.M., Stapleton, F.B., Oh, W., Whitley, R.J. (eds) Textbook of Clinical Pediatrics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02202-9_22
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