Skip to main content

ECMO (Extracorporeal Membrane Oxygenation)

  • Reference work entry
Textbook of Clinical Pediatrics
  • 335 Accesses

Introduction

Extracorporeal membrane oxygenation (ECMO) is an effective, but costly and invasive rescue therapy for term and late preterm infants with reversible heart and/or lung failure unresponsive to maximal conventional therapies. These include less invasive newer technologies, such as, high-frequency ventilation, surfactant replacement therapy, and inhaled nitric oxide (iNO). ECMO is the application of modified extracorporeal bypass technology for a period of days to weeks to provide temporary life support allowing the injured lungs and/or heart to recover. The first successful clinical application in infants was reported by Bartlett in 1976 and the treatment began to be adopted widely in the mid to late 1980s. ECMO has been shown to significantly improve mortality in a randomized controlled trial and has been the standard of care in industrialized countries for over 20 years. Availability in less-developed countries is limited due to its high expense, need for sophisticated...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 999.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 1,299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Conrad SA, Rycus PT, Dalton H (2005 Jan-Feb) Extracorporeal Life Support Registry Report 2004. ASAIO J 51(1):4–10

    Article  PubMed  Google Scholar 

  • ECLS Registry Report International Summary Extracorporeal Life Support Organization, January, 2010

    Google Scholar 

  • Fliman PJ, de Regnier RA, Kinsella JP, Reynolds M, Rankin LL, Steinhorn RH (2006 May) Neonatal extracorporeal life support: impact of new therapies on survival. J Pediatr 148(5):595–599

    Article  PubMed  Google Scholar 

  • Keckler SJ, Laituri CA, Ostlie DJ, St Peter SD (2010 Jan) A review of venovenous and venoarterial extracorporeal membrane oxygenation in neonates and children. Eur J Pediatr Surg 20(1):1–4

    Article  PubMed  CAS  Google Scholar 

  • Keszler M, Ryckman FC, McDonald JV Jr et al (1992) A prospective multi-center randomized study of high vs. Low positive end-expiratory pressure during extracorporeal membrane oxygenation. J Pediatr 120:107–113

    Article  PubMed  CAS  Google Scholar 

  • Morini F, Goldman A, Pierro A (2006 Dec) Extracorporeal membrane oxygenation in infants with congenital diaphragmatic hernia: a systematic review of the evidence. Eur J Pediatr Surg 16(6):385–391

    Article  PubMed  CAS  Google Scholar 

  • Mugford M, Elbourne D, Field D (2008 Jul) Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants. Cochrane Database Syst Rev 16(3):CD001340, Review

    Google Scholar 

  • (1996) UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. UK Collaborative ECMO Trial Group. Lancet 348(9020):75–82

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Martin Keszler .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Keszler, M. (2012). ECMO (Extracorporeal Membrane Oxygenation). In: Elzouki, A.Y., Harfi, H.A., Nazer, H.M., Stapleton, F.B., Oh, W., Whitley, R.J. (eds) Textbook of Clinical Pediatrics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02202-9_22

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-02202-9_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-02201-2

  • Online ISBN: 978-3-642-02202-9

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics