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Childhood Polyarteritis Nodosa

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Textbook of Clinical Pediatrics

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Definition/Classification

Polyarteritis nodosa (PAN) is a clinical syndrome with a wide variety of signs and symptoms, which are caused by fibrinoid necrosis of small and/or medium-sized arteries. Two disease entities are defined: classical PAN and cutaneous PAN. Microscopic PAN will be discussed in another section. Patients are often classified as PAN based on existing criteria. The recent EULAR/PRINTO/PRES (Ankara) criteria propose the need for a biopsy showing characteristic histological features of PAN or angiography reflecting the mid-size arteritis, as mandatory criteria for the classification of a child as PAN (Table 166.1 ).

Table 166.1 Classification of PAN (Ozen et al. (2010))
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Authors and Affiliations

  1. Department of Pediatrics, Hacettepe University Faculty of Medicine, 06100, Sihhiye, Ankara, Turkey

    Dr. Fatih Ozaltin M.D. & Seza Ozen M.D. (Professor)

Authors
  1. Dr. Fatih Ozaltin M.D.
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  2. Seza Ozen M.D.
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Corresponding author

Correspondence to Fatih Ozaltin M.D. .

Editor information

Editors and Affiliations

  1. Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia

    Abdelaziz Y. Elzouki (Professor of Pediatrics) (Professor of Pediatrics)

  2. National Center of Allergy, Asthma & Immunology (NCAAI), Riyadh, Saudi Arabia

    Harb A. Harfi (Director) (Director)

  3. Consultant Pediatric Gastroenterology & Hepatology, Islamic Hospital, Amman, Jordan

    Hisham M. Nazer

  4. Seattle Children's Hospital University of Washington, School of Medicine, Seattle, WA, USA

    F. Bruder Stapleton (Professor and Chair Department of Pediatrics) (Professor and Chair Department of Pediatrics)

  5. Alpert Medical School of Brown University, Woman and Infants Hospital, Providence, RI, USA

    William Oh (Professor of Pediatrics) (Professor of Pediatrics)

  6. University of Alabama, Birmingham, AL, USA

    Richard J. Whitley (Professor of Pediatrics) (Professor of Pediatrics)

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© 2012 Springer-Verlag Berlin Heidelberg

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Ozaltin, F., Ozen, S. (2012). Childhood Polyarteritis Nodosa. In: Elzouki, A.Y., Harfi, H.A., Nazer, H.M., Stapleton, F.B., Oh, W., Whitley, R.J. (eds) Textbook of Clinical Pediatrics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02202-9_166

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  • DOI: https://doi.org/10.1007/978-3-642-02202-9_166

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-02201-2

  • Online ISBN: 978-3-642-02202-9

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