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Anaphylactic Shock

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Encyclopedia of Intensive Care Medicine

Synonyms

Allergic shock; Anaphylaxis

Definition

Anaphylaxis is a medical emergency that requires immediate diagnosis and treatment in order to avoid life-threatening consequences. Definitions of anaphylaxis have conflicted over the years; however, recent clarity has emerged based on consensus symposia. In simple terms, “anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death” [1]. More detailed revisions of the definition [1] for health professionals using clinical criteria suggest that anaphylaxis is highly likely when any one of the following three criteria occurs:

  1. 1.

    Acute onset of an illness (minutes to several hours) with involvement of the skin and/or mucosal tissue (e.g., hives/urticaria, pruritus, flushing, swollen lips, tongue, or uvula) associated with at least one of the following:

    1. (a)

      Respiratory compromise (e.g., dyspnea, wheeze, and/or stridor)

    2. (b)

      Reduced blood pressure

    3. (c)

      Associated symptoms of organ dysfunction (e.g., hypotonia, syncope,...

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References

  1. Sampson HA, Munoz-Furlong A, Bock SA, Schmitt C, Bass R, Chowdhury BA, Decker WW, Furlong TJ, Galli SJ, Golden DB, Gruchalla RS, Harlor AD Jr, Hepner DL, Howarth M, Kaplan AP, Levy JH, Lewis LM, Lieberman PL, Metcalfe DD, Murphy R, Pollart SM, Pumphrey RS, Rosenwasser LJ, Simons FE, Wood JP, Camargo CA Jr (2005) Symposium on the definition and management of anaphylaxis: summary report. J Allergy Clin Immunol 115(3):584–591

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  2. Simons FE (2008) Emergency treatment of anaphylaxis. Brit Med J 336(7654):1141–1142

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  3. Gaeta TJ, Clark S, Pelletier AJ, Camargo CA (2007) National study of US emergency department visits for acute allergic reactions, 1993 to 2004. Ann Allergy Asthma Immunol 98(4):360–365

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  4. Simons FE, Gu X, Simons KJ (2001) Epinephrine absorption in adults: intramuscular versus subcutaneous injection. J Allergy Clin Immunol 108(5):871–873

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  5. Winbery SL, Lieberman PL (2002) Histamine and antihistamines in anaphylaxis. Clin Allergy Immunol 17:287–317

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Correspondence to Brian H. Rowe M.D., M.Sc., CCFP(EM) FCCP .

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© 2012 Springer-Verlag Berlin Heidelberg

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Rowe, B.H. (2012). Anaphylactic Shock. In: Vincent, JL., Hall, J.B. (eds) Encyclopedia of Intensive Care Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00418-6_800

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  • DOI: https://doi.org/10.1007/978-3-642-00418-6_800

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-00417-9

  • Online ISBN: 978-3-642-00418-6

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