Zusammenfassung
Die wichtigsten Teilgebiete, in denen zukünftig we sentliche Neuerungen zu erwarten sind, umfassen:
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Onkologie von Kopf-Hals-Tumoren einschließlich Stammzelltherapie
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Gentherapie und „new targets“
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Regeneration von Strukturen des Innenohrs
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gezielte medikamentöse Therapie bestimmter Organe („drug delivery“)
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Implantate neuen Designs und mit modifizierten, „biologisierten“ Oberflächen
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Literatur
Bermingham NA, Hassan BA, Price SD et al. (1999) Math1: an essential gene for the generation of inner ear hair cells. Science 284: 1837–1841
Dazert S, Muller AM (2002) Stammzellbiotechnologie — Revolution etablierter Therapieverfahren? Laryngorhinootologie 81 (Suppl 1): S24–S38
Guntinas-Lichius O (2002) Wachstumstaktoren in der Hals-Nasen-Ohren-Heilkunde. Laryngorhinootologie 81 (Suppl 1): S39–S60
Hol MK, Bosman AJ, Snik AF, Mylanus EA, Cremers CW (2005) Bone-anchored hearing aids in unilateral inner ear deafness: an evaluation of audiometric and patient outcome measurements. Otol Neurotol 26: 999–1006
Izumikawa M, Minoda R, Kawamoto K et al. (2005) Auditory hair cell replacement and hearing improvement by Atoh 1 gene therapy in deaf mammals. Nat Med 11: 2/1–2/6
Jennissen HP, Zumbrink T, Chatzinikolaidou M, Steppuhn J (1999) Biocoating of implants with mediator molecules: Surface enhancement of metals by treatment with chromosulfuric acid. Materialwissenschaft Werkstofftechnik 30: 838–845
Jiang Y, Jahagirdar BN, Reinhardt RL et al. (2002) Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418: 41–49
Li H, Roblin G, Liu H, Heller S (2003) Generation of hair cells by stepwise differentiation of embryonic stem cells. Proc Natl Acad Sci USA 100: 13495–13500
Neumann A, Jahnke K (2003) Biomaterials for ossicular chain reconstruction. A Review. Materialwissenschaft Werkstofftechnik 34: 1052–1057
Stone JS, Rubel EW (2000) Cellular studies of auditory hair cell regeneration in birds. Proc Natl Acad Sci USA 97: 11714–11721
Zheng JL, Gao WQ (2000) Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat Neurosci 3: 580–586
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Brors, D., Neumann, A. (2009). Perspektivische Therapieformen. In: Reiß, M. (eds) Facharztwissen HNO-Heilkunde. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-89441-4_22
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